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Hi all, posting on this forum as I found it on google and find there are a lot of people on here who are familiar with these sorts of issues. Hopefully you can help.
Long story short, 30 year old male. 5'11", 150lbs. Never used any anabolic steroids. Take hydrocortisone and DHEA daily for adrenal insufficiency. Had these issues prior to being on both HC and DHEA.
Lab work:
863ng/dl Total testosterone
138.1pg/mL Free Testosterone (35-155)
DHEA in the 150-200 range pre supplementation, now 350-400 on 100mg DHEA/day
Thyroids are good, urinary iodine is always severely low, even while supplementing. Strange.
Other than that, nothing remarkable.
Here's my issue. I have no issue getting hard when aroused. Often wake up with morning wood, and once I 'get going' I don't have issue. I've experiemented with tadalafil and sildenafil. They work when I am aroused. When I am not aroused, they don't do anything. If I consume cannabis I sometimes get a massive surge of libido and all issues go away. My issue is that a lot of the time I simply have no response sexually or mentally until I'm actively engaging in sex. I used to get rock hard if I hugged a woman when I was younger, now I've had extremely hot strippers on my lap and had zero response at times. I have experimented with various drugs and antidepressants, with no significant results. I.e. bupropion, selegiline, etc. However, the drug 'pramipexole' seemed to be the one that actually induced rock hard morning wood and somewhat of a libido, but had some side effects. The combination of pramipexole + some weed can turn me into someone who can't get rid of their erection, the opposite problem I normally have. High doses of zinc sometimes help. Eating a ton of raw oysters does the trick as well, yet I don't notice the same from high dose zinc supplementation.
I've developed a stack that works every time but at age 30 I don't really want to have to take a bunch of drugs to function sexually like I should. This includes low dose of pramipexole, weed, yohimbine hcl, phenibut, tadalafil. Sometimes one or two shots of alcohol can also help things, maybe due to the anxiety relieving factor.
Here's the other issue. After a few weeks of abstaining from ejaculation, things slowly improve. Then sometimes after ejaculating, I will go days, sometimes weeks while having literally zero libido. Morning wood disappears, and I feel dead inside, have really bad depression, fatigue, etc. I suspect I may have some rare illness called "Post Orgasmic Illness Syndrome/POIS". I start feeling good in the 2-3 week after ejaculation range and typically that is when the cycle repeats itself. However, I don't notice all that much with prolactin lowering supplements or drugs, besides pramipexole. I also suffer from what I would categorize as melancholic depression.
Wet dreams barely cause symptoms, maybe 1/10th as significant as a normal orgasm.
This has put me in a weird spot where I am basically forced to abstain from sex or suffer the consequences of feeling like absolute trash after ejaculating. If I go multiple rounds, I could be laid up and useless for a week or two.
So basically, once sex starts, or she starts giving me head, I can get it up and have no issue performing. But the anticipation of sex is not having the response that it should. My T levels seem fine. I'm assuming this is depression/dopamine related? If anyone has any ideas, I would really appreciate your input. If there are any labs I should have done, let me know. Take care all.
Long story short, 30 year old male. 5'11", 150lbs. Never used any anabolic steroids. Take hydrocortisone and DHEA daily for adrenal insufficiency. Had these issues prior to being on both HC and DHEA.
Lab work:
863ng/dl Total testosterone
138.1pg/mL Free Testosterone (35-155)
DHEA in the 150-200 range pre supplementation, now 350-400 on 100mg DHEA/day
Thyroids are good, urinary iodine is always severely low, even while supplementing. Strange.
Other than that, nothing remarkable.
Here's my issue. I have no issue getting hard when aroused. Often wake up with morning wood, and once I 'get going' I don't have issue. I've experiemented with tadalafil and sildenafil. They work when I am aroused. When I am not aroused, they don't do anything. If I consume cannabis I sometimes get a massive surge of libido and all issues go away. My issue is that a lot of the time I simply have no response sexually or mentally until I'm actively engaging in sex. I used to get rock hard if I hugged a woman when I was younger, now I've had extremely hot strippers on my lap and had zero response at times. I have experimented with various drugs and antidepressants, with no significant results. I.e. bupropion, selegiline, etc. However, the drug 'pramipexole' seemed to be the one that actually induced rock hard morning wood and somewhat of a libido, but had some side effects. The combination of pramipexole + some weed can turn me into someone who can't get rid of their erection, the opposite problem I normally have. High doses of zinc sometimes help. Eating a ton of raw oysters does the trick as well, yet I don't notice the same from high dose zinc supplementation.
I've developed a stack that works every time but at age 30 I don't really want to have to take a bunch of drugs to function sexually like I should. This includes low dose of pramipexole, weed, yohimbine hcl, phenibut, tadalafil. Sometimes one or two shots of alcohol can also help things, maybe due to the anxiety relieving factor.
Here's the other issue. After a few weeks of abstaining from ejaculation, things slowly improve. Then sometimes after ejaculating, I will go days, sometimes weeks while having literally zero libido. Morning wood disappears, and I feel dead inside, have really bad depression, fatigue, etc. I suspect I may have some rare illness called "Post Orgasmic Illness Syndrome/POIS". I start feeling good in the 2-3 week after ejaculation range and typically that is when the cycle repeats itself. However, I don't notice all that much with prolactin lowering supplements or drugs, besides pramipexole. I also suffer from what I would categorize as melancholic depression.
Wet dreams barely cause symptoms, maybe 1/10th as significant as a normal orgasm.
This has put me in a weird spot where I am basically forced to abstain from sex or suffer the consequences of feeling like absolute trash after ejaculating. If I go multiple rounds, I could be laid up and useless for a week or two.
So basically, once sex starts, or she starts giving me head, I can get it up and have no issue performing. But the anticipation of sex is not having the response that it should. My T levels seem fine. I'm assuming this is depression/dopamine related? If anyone has any ideas, I would really appreciate your input. If there are any labs I should have done, let me know. Take care all.
