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**broken link removed**
This got published on the 31st, got to love the early release and free articles.
CTP-modified hGH (MOD-4023) was administered weekly at a dose of either 0.25, 0.48, or 0.66 mg/kg/week, and compared to daily hGH at a dose of 0.24 mg/kg/week.
MOD-4023 showed an estimated half-life approximately 5- to 10-fold longer when compared to daily r-hGH. IGF-I and IGFBP-3 showed dose-dependent increase during MOD-4023 treatment. IGF-I SDS for MOD-4023 did not exceed +2. All MOD-4023 cohorts demonstrated adequate catch-up growth. The 0.66 mg/kg/week dose demonstrated efficacy closest to daily r-hGH. No serious adverse events were observed during MOD-4023 treatment, and its tolerability was consistent with known properties of r-hGH.
Seems promising for patients,practitioners..with clear implications in sports and bodybuilding.
This got published on the 31st, got to love the early release and free articles.
CTP-modified hGH (MOD-4023) was administered weekly at a dose of either 0.25, 0.48, or 0.66 mg/kg/week, and compared to daily hGH at a dose of 0.24 mg/kg/week.
MOD-4023 showed an estimated half-life approximately 5- to 10-fold longer when compared to daily r-hGH. IGF-I and IGFBP-3 showed dose-dependent increase during MOD-4023 treatment. IGF-I SDS for MOD-4023 did not exceed +2. All MOD-4023 cohorts demonstrated adequate catch-up growth. The 0.66 mg/kg/week dose demonstrated efficacy closest to daily r-hGH. No serious adverse events were observed during MOD-4023 treatment, and its tolerability was consistent with known properties of r-hGH.
Seems promising for patients,practitioners..with clear implications in sports and bodybuilding.