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Loss of sleep with use of Anastrozole anyone?

Unmoto

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Aug 26, 2012
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Since incorporating the anti-E Anastrozole into my HRT protocol, I have been experiencing unrelenting sleep loss. Been getting, on average, about 4 hours sleep per night. I stopped taking the Anastrozole about a week ago and I am sleeping much better.

I am very satisfied with my results in the gym and my libido. Great post-workout pumps and extra hard erections. The down side is that fluffiness has crept up on me and my muscle definition has faded some. Have any of you had the same issues while on HRT and using an anti-E?

45yo
6'0"
180lbs
10-13% bf

Test E @ 250mg per week
Anastrozole @ .25mg ed
Proviron @ 25 mg ed
 

cornertech

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Jun 25, 2012
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Since incorporating the anti-E Anastrozole into my HRT protocol, I have been experiencing unrelenting sleep loss. Been getting, on average, about 4 hours sleep per night. I stopped taking the Anastrozole about a week ago and I am sleeping much better.

I am very satisfied with my results in the gym and my libido. Great post-workout pumps and extra hard erections. The down side is that fluffiness has crept up on me and my muscle definition has faded some. Have any of you had the same issues while on HRT and using an anti-E?

45yo
6'0"
180lbs
10-13% bf

Test E @ 250mg per week
Anastrozole @ .25mg ed
Proviron @ 25 mg ed

Ummm...I will have to pay more attention to that...I don't use an anti-E everyday...but my sleep isn't great either...Ususally the anti-e aid in losing the bloat for me...
 

surfbh

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Dec 31, 2010
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105
It will effect my sleep sometimes by making me have to piss a lot as my E and water bloat go down.
 

Unmoto

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Aug 26, 2012
Messages
129
Thanks for the responses fellas. It looks like I may not be alone in this.
 

smcstevesmc

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Apr 14, 2013
Messages
115
Dont forget Androgens are stimulating so maybe you should check e2 levels?

.. Maybe take adex eod or take less, are you having any other sides? Ever tried exemestane? I have only used adex and letro, letro was way too strong and ai had sides of night peeing and unfestful sleep ans even sexdrive issues.
 

Goody

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Feb 2, 2010
Messages
992
Its very hard to nail down the proper A.I. dosage...took me about a year of experiementing....
maybe try.25 EOD or E3D...you might simply be using to much...you gotta find your sweet spot....once you think you've got it pull some bloods to see
 

Unmoto

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Aug 26, 2012
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Added some Proviron

The two previous posts were enlightening. Since this post, I have stopped taking lowered my dosage of Anastrozole to .25 e3d and I am sleeping normal again. My morning wood became less frequent, so I added 50mg of Proviron split into two doses per day. I feel good. Morning wood is raging at times and it looks like my bf has gone down some. A little bit of Proviron seems do the trick if anastrozole causes issues.
 

Goody

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Its tricky for sure...glad you found some relief...there were times I thought I had finally nailed it and I'd pull bloods and...nope...outta range again one way or another.
 

Ehren

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Its tricky for sure...glad you found some relief...there were times I thought I had finally nailed it and I'd pull bloods and...nope...outta range again one way or another.

Did you finally figure it out?
 

Cerberus777

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When taking an AI you need to keep an eye on t3 and prolactin. If prolactin raises or t3 falls...and estrogen falls you will have sleep issues.
 

Simpllyhuge

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What do you mean by, if estrogen falls. I thought that was the point of taking an AI
 

Cerberus777

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Yes true. But if your hormones are off. T3 may go down with estrogen. And prolactin can rise if estrogen is low... This can cause poor sleep.
 

FRKNHUGE

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all the above advice given above is good
my adex dose was to be 1mg every fourth day basically(8tb/month divided)
i chose to run .25mg every fourth with such a low dose of T(300mg) along with my hcg 500iu 2x a week and it seems to be my sweet spot for estro balance.
if your wiping out estro completely that too is not good.
try cutting back a bit and see if this helps out.
frk
 

tokon

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Aug 30, 2008
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Yes true. But if your hormones are off. T3 may go down with estrogen. And prolactin can rise if estrogen is low... This can cause poor sleep.

this is one of the main probs with trt imo. there is a wide and individual range of "balance" between the various hormones and, once you start messing with one, it easy to throw it all out.
 

PoptartPsycho

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all the above advice given above is good
my adex dose was to be 1mg every fourth day basically(8tb/month divided)
i chose to run .25mg every fourth with such a low dose of T(300mg) along with my hcg 500iu 2x a week and it seems to be my sweet spot for estro balance.
if your wiping out estro completely that too is not good.
try cutting back a bit and see if this helps out.
frk


This is the same protocol that my doc has me on. 1mg on Monday and Thursday. (along with HCG on those same days).

I am only getting 200mg test weekly though. How did you measure in order to get 300mg weekly? Cause my last blood work my test was a 25. (not a typo). I doubt you could have been lower than me.)
 

FRKNHUGE

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no i was at 104 lol still pre adolescent female levels lol

300 would be 1.5ml with 200mg tc
in other words id do .75 twice weekly to maintain steadier levels.
like i said i dont take the recomended adex dose tho, i use .25mg as needed, usually once or twice a week max.
1mg is far too high a dose IMO for that level of T even weekly
 
Last edited:

PoptartPsycho

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451
Well I am 79 points lower than you but he only gave me 200mg weekly. Oh well.

I start Monday and go 60 days before having bloods and seeing him again. Well see what the #s say then. But I am not doing the full tab on those days like he says. Like you, I think it is too much.
 

smcstevesmc

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Only 200? LOL

I had to fight for 100mg/wk as it puts me above 1,000ng/dl.

I feel best on 200-300/wk but nobody will even write my arimidex script and I'm naturally high with e2. I felt best treating myself but the wifey doesnt like that.

Also, dont take proviron untill you get your adex.dose right. DHT drugs affect e2 and free test levels.
 
Last edited:

epoxy

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Haha damn. I've been taking .25mg Adex for 2 weeks now ED!!!! No sleep problems for me. I am super prone to gyno issues, though.
 

Goody

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Did you finally figure it out?

Yes, for the most part...
My problem was high residual e2 from when I would blast a bit...the dose I was taking just wouldn't bring it down.
So basically I decided to crush my e2 levels and start from scratch...I felt like crap when it was crushed...felt like I had glass in my elbows and every joint popped and had zero interest in sex.
Then I just let it come back to the sweet spot on its own...took a couple weeks...kept a journal about how I felt each day...any morning wood etc...
Was able to take .25mgs once a week and keep e2 good....
I still wasn't very happy with the sex drive though...the adex seemed to knock it off even when I was in range so lately I am injecting 20mgs 6 days a week Subq and seeing if I can get by with no A.I. at all this way...getting labs this week so we'll see. I can tell you in the 4 weeks or so doing it this way I feel much better and sex drive is thru the roof...almost like when Im blasting. Energy, mood, everything feels better.
 

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