Low Progesteron

Fa Seeshus · Feb 3, 2021

RDS said:
hcg improves your libido?

For me it improves mood and libido.

Matsuo Munefusa · Feb 3, 2021

Looks like you can get pharm grade progesterone micronized 97% - 103% (lol) purity for around $4/g

goback2013 · Feb 3, 2021

Matsuo Munefusa said:
Looks like you can get pharm grade progesterone micronized 97% - 103% (lol) purity for around $4/g

from where ? ali babba or india mart ?

XXL · Feb 3, 2021

bigains said:
I am only taking the equivilaint of what a normal male should produce in a day. Being on test long term can cause shut down of multiple hormones. This can have an effect things like mood, and sex drive. Hcg is another way of increasing the production of progesterone, dhea and pregenolone.

Yes test can shut down the cells in the testes that make pregnenlone so it’s important to test occasionally..... Which is a precursor to progest. I would think preg would be more effective feeding the pathway.

Matsuo Munefusa · Feb 3, 2021

XXL said:
Yes test can shut down the cells in the testes that make pregnenlone so it’s important to test occasionally..... Which is a precursor to progest. I would think preg would be more effective feeding the pathway.

I think so too, completely backfill the pathway. However you could see a significant jump in estrogens from supplement with pregnenolone is my understanding...not sure how much would convert to estrogen in an enhanced dude though.

Progesterone shouldn’t increase estrogen though in my understanding, of anything it should antagonize estrogen.

Maybe somebody like @Stewie can drop by...

XXL · Feb 4, 2021

Matsuo Munefusa said:
I think so too, completely backfill the pathway. However you could see a significant jump in estrogens from supplement with pregnenolone is my understanding...not sure how much would convert to estrogen in an enhanced dude though.

Progesterone shouldn’t increase estrogen though in my understanding, of anything it should antagonize estrogen.

Maybe somebody like @Stewie can drop by...

Yes. Progest can inc estrogen I think by freeing up receptors. Maybe I am making that up, not sure. Preg makes all and most steroidal hormones, when needed. If anything taking dhea will increase estrogen

Matsuo Munefusa · Feb 4, 2021

XXL said:
Yes. Progest can inc estrogen I think by freeing up receptors. Maybe I am making that up, not sure. Preg makes all and most steroidal hormones, when needed. If anything taking dhea will increase estrogen

I’ve been reading up on how progesterone can actually change the estrogen receptor, make it less sensitive in laymen’s terms. This makes sense to me at least and would explain why I’ve gotten so estrogen sensitive progressively over the past 10 years on TRT.

I would really need somebody with more biochemistry knowledge to confirm that though. I’m not the best at interpreting studies.

RDS · Feb 4, 2021

Fa Seeshus said:
For me it improves mood and libido.

Cool, and are you just doing the standard 250iu 3x a week?

Matsuo Munefusa · Feb 4, 2021

Bump for @Kaladryn

Hopefully one of our smart dudes will see this.

Fa Seeshus · Feb 4, 2021

RDS said:
Cool, and are you just doing the standard 250iu 3x a week?

Yeah. I do that for a few months and when I stop doing that I switch back to adding oral dhea and pregnenolone daily. When you are on long term test these backflow hormones get suppressed and can cause issues. Again not much point in doing them when on HCG as that will boost them.

RDS · Feb 4, 2021

Fa Seeshus said:
Yeah. I do that for a few months and when I stop doing that I switch back to adding oral dhea and pregnenolone daily. When you are on long term test these backflow hormones get suppressed and can cause issues. Again not much point in doing them when on HCG as that will boost them.

That’s really helpful, man. Thanks

Rumpwrangler · Feb 7, 2021

goback2013 said:

Any luck sourcing the Etifoxine?

goback2013 · Feb 7, 2021

Rumpwrangler said:
Any luck sourcing the Etifoxine?

seems available at the usual international marts..

Zarati · Feb 8, 2021

Matsuo Munefusa said:
I think so too, completely backfill the pathway. However you could see a significant jump in estrogens from supplement with pregnenolone is my understanding...not sure how much would convert to estrogen in an enhanced dude though.

Progesterone shouldn’t increase estrogen though in my understanding, of anything it should antagonize estrogen.

Maybe somebody like @Stewie can drop by...

New chick I'm dating has high estrogen, so her doc has her taking progesterone to lower her estrogen.

Matsuo Munefusa · Feb 8, 2021

Zarati said:
New chick I'm dating has high estrogen, so her doc has her taking progesterone to lower her estrogen.

Yeah I’ve been obsessively reading about progesterone since I made this post. Deca (a progestin) always filled me out but gave me gyno but just started 3 days ago natural progesterone and literally overnight felt better. Slept deeper, nipples got way less sensitive, some water weight came off and somehow muscles filled out. I was for sure deficient.

I’ve been reading about protein synthesis and progesterone and apparently it’s pretty key so I’m hopeful long term could see some recomposition. I don’t want to gain any more weight but I could shed 1-2% body fat and gain a few pounds muscle over the next year, surely.

Matsuo Munefusa · Feb 8, 2021

Thank you @bigains for sending me down that Leo rabbit hole.

@strongerlife I’d recommend trying the cream if you tested out deficient. It’s a fucking game changer.

I don’t have any doubt the cream absorbs. I got some numbness on my torso yesterday (typical side) and about 2 hours after putting cream on I get very sleepy.

The one drawback people discuss is that it can lower DHT and drop libido. It’s fine for us, we’re on TRT and can bump test up a tiny bit or add a small dose of masteron or primo to replace lost DHT.