Lowndose trestolone

[warlock]

Its anecdotal at this time.
Not having tried the compound myself.
Im carrying the information over for educational purposes only.
Prominent TRT doctor is actually dispensing Trestolone (not FDA approved) to enhance the overall TRT experience. My information is from a very METICULOUS athlete, under his care soon to be 60 who is very please at this ratio/dosage along with his associates doing the same thing. I hope I can share more concrete backing to this theory, I am not under that physicians care at this time.

That sounds really appealing. Thanks for sharing. Hopefully, you can share more feedback as they get deeper into the protocol.

 

[jcc80]

Are you doing daily injections with trest decanoate? Is there a reason for doing it that often? I haven't tried trest d yet, but I have some on the way. I was going to try it once a week.

Yeah, same reason I do test enanthate daily despite the long ester. Stable levels, hopefully less e2 conversion because it's not all hitting at once. It's kind of a chore, but I'm not getting the crazy estrogen issues that everyone warns you about with trestolone.

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[nothuman]

I haven't really heard much on whether it raises BP and heart rate. Can anyone shed light on this?

 

[Prada]

Have you noticed any hair loss or thinning with trestolone compared to other compounds?

Yes I would like to know as well. :lightbulb:

 

[TheOtherOne55]

I mean all of this sounds super nice as Trest was tested as a TRT replacement hormone. But Trest was ALSO tested as a male contraceptive.

I would try this in a heartbeat, but even at a low dose like this I'm afraid of the reproductive reproductions. I know I still have swimmers but Trest seems to sound like the KING of shutdown and goodbye to kids-in-the-future options.

Anyone have any thoughts on this?

 

[danieltx]

I mean all of this sounds super nice as Trest was tested as a TRT replacement hormone. But Trest was ALSO tested as a male contraceptive.

I would try this in a heartbeat, but even at a low dose like this I'm afraid of the reproductive reproductions. I know I still have swimmers but Trest seems to sound like the KING of shutdown and goodbye to kids-in-the-future options.

Anyone have any thoughts on this?

Trestolone was trialed but it wasn't effective enough to pass as a contraceptive. With the insane amount of money in the pharmaceutical industry and the want for condom / vasectomy alternatives, you know they'd have rushed it to market if it worked.

I believe the chances of a man becoming infertile strictly from hormone use alone are almost nonexistent. If one uses hormones and has fertility issues after, they probably still would've had them had they never used hormones. I've never seen a clinical case where a man was rendered permanently infertile due only to hormone use.

 

[nothuman]

I mean all of this sounds super nice as Trest was tested as a TRT replacement hormone. But Trest was ALSO tested as a male contraceptive.

I would try this in a heartbeat, but even at a low dose like this I'm afraid of the reproductive reproductions. I know I still have swimmers but Trest seems to sound like the KING of shutdown and goodbye to kids-in-the-future options.

Anyone have any thoughts on this?

Hey bud check this out
https://www.tigerfitness.com/blogs/supplements/trestalone-ment-7alpha-methyl-19-nortestostrone

Seems like the suppression goes away once you stop, but it’s definitely a valid concern regardless.

 

[t.c.jones]

Whoa!!! All of this got me very interested in trying Trest with my trt


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[Fa Seeshus]

The suppressive nature is interesting. If I'm using 250iu HCG 2x a week on TRT test to maintain some semblance of nuts, would the trest interfere with that?

 

[MyNameIsJeff]

The suppressive nature is interesting. If I'm using 250iu HCG 2x a week on TRT test to maintain some semblance of nuts, would the trest interfere with that?

It's does dependent of course, but at 400mg per week, Treat made my balls shrink like no other steroid. My cum even turned into a clumpy jelly, which indicates severe suppression. Trying to counter this with 250IU HCG per day was unsuccessful. Trestolone has a strong progestogenic effect, which is a double whammy w.r.t. suppression of testicular function.

Synthetic progestins such as levonorgestrel (LNG) are used in combination with testosterone (T) in male contraceptive clinical trials to suppress gonadotropins secretion, but whether progestins have additional direct effects on the testis are not known. This study aimed to examine the effect of a potent progestin, (LNG), alone or in combination with testosterone (T) on spermatogenesis in adult rats, and to evaluate the functional role of the progesterone receptors (PRs) in the testis. In comparison with a low dose of LNG treatment in adult rats for 4 weeks, T and T + LNG treatment decreased testicular sperm count to 64.1 and 40.2% of control levels respectively. LNG induced germ cell apoptosis at stages I-IV and XII-XIV; T increased apoptosis at stages VII-VIII; LNG + T treatment induced greater germ cell apoptosis at a wider range of seminiferous epithelial stages. RT-PCR and Western Blots showed that PR was present in testes and up-regulated during suppression of spermatogenesis induced by testicular hormonal deprivation. PR knockout (PRKO) mice had larger testes, greater sperm production, increased numbers of Sertoli and Leydig cells. Suppression of gonadotropin and intratesticular T by GnRH-antagonist treatment induced PR promoter driven LacZ expression in Leydig cells of PRKO mice. This suggests that GnRH-antagonist treatment while inducing germ cell apoptosis also up-regulates PR. We conclude that (i) LNG + T induced greater suppression of spermatogenesis through increase in germ cell apoptosis involving a wider range of seminiferous epithelial stages than either treatment alone, (ii) up-regulation of PR was associated with inhibition of spermatogenesis, (iii) PR knockout mice showed increased sperm production suggesting that testicular PR activated events play a physiological and pharmacological inhibitory role in the testis. These data support the hypothesis that in addition to its known suppressive effects on gonadotropins, progestins may have direct inhibitory actions on the testis.

https://www.ncbi.nlm.nih.gov/pubmed/23408752

 

[m314]

The suppressive nature is interesting. If I'm using 250iu HCG 2x a week on TRT test to maintain some semblance of nuts, would the trest interfere with that?

I've been on test and HCG year round for 10 years. Trestolone doesn't change my ball size when I add it in.

 

[nothuman]

It's does dependent of course, but at 400mg per week, Treat made my balls shrink like no other steroid. My cum even turned into a clumpy jelly, which indicates severe suppression. Trying to counter this with 250IU HCG per day was unsuccessful. Trestolone has a strong progestogenic effect, which is a double whammy w.r.t. suppression of testicular function.


https://www.ncbi.nlm.nih.gov/pubmed/23408752

Did that all normalize once you came off, and if so, how long after?

 

[guest1337]

I haven't really heard much on whether it raises BP and heart rate. Can anyone shed light on this?

I've ran it multiple times and have not noticed an increase in either.

 

[nothuman]

I've ran it multiple times and have not noticed an increase in either.

What was your dose?

 

[MyNameIsJeff]

Did that all normalize once you came off, and if so, how long after?

yeah, normalized within weeks no problem

 

[Slowmoe]

Can anyone comment on the "feel" of trest A vs trest D?

 

[m314]

I haven't really heard much on whether it raises BP and heart rate. Can anyone shed light on this?

Low(ish) doses don't raise my BP except in extreme situations. Major life drama can cause my BP to go higher than it would normally be on trest. It's rare, though.

 

[m314]

Can anyone comment on the "feel" of trest A vs trest D?

I haven't tried trest d yet, but I've tried acetate and enanthate. I'm a couple weeks into my new cycle with trest e. They both feel pretty much the same to me other than the time it takes to kick in.

 

[madmuscle25]

PM sent m314.

 

[Slowmoe]

LETS NOT FORGET THAT TREST DOES NOT BIND TO SHBG. So 100mg/ week trest would have you with the same free androgen as probably 500-1000mg a week of test. And the free androgen is much more potent mg for mg aside from the shbg issue.

Someone correct me if I'm wrong.