- Joined
- Oct 20, 2016
- Messages
- 292
Check out this research, where melatonin, reservatrol and letrozole were added into breast adipose tissue in vitro.
As we know, aromatisation of testosterone to estrogen can occur at the aromatase enzyme in fat cells.
Both melatonin and reservatrol were found to act as aromatase inhibitors in this co-culture model, however, melatonin was 1000x more potent than reservatrol.
The most surprising finding here was that melatonin was equally as potent as letrozole!
Anti-aromatase effect of resveratrol and melatonin on hormonal positive breast cancer cells co-cultured with breast adipose fibroblasts - ScienceDirect
Sent from my iPhone using Tapatalk
As we know, aromatisation of testosterone to estrogen can occur at the aromatase enzyme in fat cells.
Both melatonin and reservatrol were found to act as aromatase inhibitors in this co-culture model, however, melatonin was 1000x more potent than reservatrol.
The most surprising finding here was that melatonin was equally as potent as letrozole!
Anti-aromatase effect of resveratrol and melatonin on hormonal positive breast cancer cells co-cultured with breast adipose fibroblasts - ScienceDirect
Sent from my iPhone using Tapatalk