Methylene Blue to lower elevated hematocrit/ RBC ?

[draven]

Anyone have any real world info on if this actually corrected high levels somewhat? I can only find a few dog studies... also if any real world info what was dosing protocol to achieve “normal “ levels

 

[OldManLogan]

From curcumin on another MB thread:

https://journals.sagepub.com/doi/abs/10.3181/00379727-31-7396P

 

[curcumin]

Anyone have any real world info on if this actually corrected high levels somewhat? I can only find a few dog studies... also if any real world info what was dosing protocol to achieve “normal “ levels

I don't think its going to work for humans because the dosage needed would be too high. And they're not even sure what the mechanism is so will it even cross over to humans?

@Stewie I'd love to hear his take though

 

[Stewie]

I don't think its going to work for humans because the dosage needed would be too high. And they're not even sure what the mechanism is so will it even cross over to humans?

@Stewie I'd love to hear his take though

I'd suspect that too, given the dosage. I personally didn't see any changes with my HH years ago when I dabbled with MB.

Poor dogs.

 

[curcumin]

I'd suspect that too, given the dosage. I personally didn't see any changes with my HH years ago when I dabbled with MB.

Poor dogs.

I know right, it kinda irritated me that they administer these huge doses and induce anemia in these dogs.

I'm going to start on MB @ 10mg 3x/week on alternating days from 3x/week mucuna pruriens (l-dopa donor). I get BW every 3 months. My last HCT (2 weeks ago) was 55 so we'll see if it changes, but its been trending down for 6 months since getting better metabolic conditioning so I'm not sure how useful any data from my bloodwork will be.

 

[Stewie]

I know right, it kinda irritated me that they administer these huge doses and induce anemia in these dogs.

I'm going to start on MB @ 10mg 3x/week on alternating days from 3x/week mucuna pruriens (l-dopa donor). I get BW every 3 months. My last HCT (2 weeks ago) was 55 so we'll see if it changes, but its been trending down for 6 months since getting better metabolic conditioning so I'm not sure how useful any data from my bloodwork will be.

Just be mindful to take a look at your albumin and osmolality (configuration of-BUN, glucose and sodium) when accessing your hemoglobin and hematocrit.