There are too many variables to give a definite answer because of the differences person to person and compound to compound. What you consider moderate others may really struggle with. Some guys can take 500mg test in 1 go and feel great and others feel crap from it. Some guys get loads of side effects from deca whilst others love it. Then comes the brand and mg/ml and potential pip. I have injected 1ml of test450 and been in pain and experienced multiple side effects and I have injected 2ml (600mg) test and felt next to nothing. I get anxiety from eq so even 1ml (300mg) would be an issue but most are fine with it. Then comes the individuals current blood work and health markers such as blood pressure so response (side effects) could vary at different times for the same person nevermind when comparing 2 different people.
I use 2-3ml syringes and I never need more and most of the time I am injecting between 1-2ml and that could be EOD or twice weekly. Right now I am doing 250-300mg (1ml) test, 100mg (1ml) primo and 150mg (0.5ml) deca twice weekly and that (550mg) gives me no issues. Thinking back I do approx 500mg syringes most of the time and whilst total dose is obviously a very important factor it's more the compounds used that effects things for me. I have done 900mg (test and deca) syringes with no issues whatsoever and the other month I done a 10mg tren a syringe and woke up having a panic attack