MK-2688 imo is essential

[Human Rocket]

what kind of effect is this having on peoples libido??

I don't think ostarine has any effect on libido at recommended dosages. Neither positive nor negative.

 

[Osta-gain]

true that, would love to see an FAQ list made for this on its own thread.

Please ask away...

 

[Osta-gain]

I don't think ostarine has any effect on libido at recommended dosages. Neither positive nor negative.

Ostarine will improve your libido... not as much as test but you will have a higher sex drive...

 

[jdchaffin]

will this have any affect on the androgen receptors found in fat tissue?

 

[Osta-president]

will this have any affect on the androgen receptors found in fat tissue?

Recent research study results indicate that androgens inhibit the ability of some fat cells to store lipids by blocking a signal transduction pathway that normally supports adipocyte function. Also, androgens, but not estrogens, increase beta adrenergic receptors while decreasing alpha adrenergic receptors- which results in increased levels of epinephrine/ norepinephrine due to lack of alpha-2 receptor negative feedback and decreased fat accumulation due to epinephrine/ norepinephrine then acting on lipolysis-inducing beta receptors. This is why many users report a favorable change in body composition, or leaning out/getting harder while making gains in lean tissue. The androgens being modulated are in skeletal muscle tissue and the brain, and inhibited in the prostate.

 

[jdchaffin]

this might be a very ignorant question but what are the reasons for wanting to stimulate the androgen receptors in the brain?

 

[brutale]

this might be a very ignorant question but what are the reasons for wanting to stimulate the androgen receptors in the brain?

So that you don't find yourself watching Gray's Anatomy or Sex and the City.

 

[jdchaffin]

So that you don't find yourself watching Gray's Anatomy or Sex and the City.

lol I was wondering if it causes a response from the thyroid or pituitary or if it is supposed to increase aggression in the gym or perhaps something else entirely.

 

[Osta-gain]

lol I was wondering if it causes a response from the thyroid or pituitary or if it is supposed to increase aggression in the gym or perhaps something else entirely.

Your answer..

A selective androgen receptor modulator, or SARM, is a small molecule that binds to and selectively modulates androgen receptors depending on tissue type. In men, SARMs may be able to:

■Stimulate testosterone's action in bone, muscle and brain
■Block testosterone's action in the prostate and skin
■Either cross or not cross into the central nervous system to affect libido

GTx. Technology FAQs

 

[MrRage]

my question that confuses me with SARMS is since they up-regulate the androgen receptors in skeletal muscle... is it possible they also enhance the effects of AAS

 

[mojo jojo]

I started using MK-2866 about 2 weeks ago and I have to say that I am quite impressed. For days 1-30 is was running 300mg test 300mg deca a week and 20mg superdrol a day. Then the week after finishing taking the superdrol I took 150mg of test. By the end of the 30 dats I wasa at 230 pounds. The week following the superdrol my strength was going down and my weight began to drop to about 224. I then started the MK-2866 at 10-15mg a day (hard to measure exactly with the dropper I have). I have been on it for about 2 weeks and my weight has crept back up to 230. My strength is not like it was on the superdrol but it has stopped decreasing.

I am now going to stop taking all test and just take the MK-2866 with clomid, HCG, and DAA to see if I can get myself to somewhat normal levels again. I am prescribed 200mg test every 2 weeks and I have been taking that for a while. I would like to see if I can get myself going again with this combo while not loosing any size.

 

[jdchaffin]

I started using MK-2866 about 2 weeks ago and I have to say that I am quite impressed. For days 1-30 is was running 300mg test 300mg deca a week and 20mg superdrol a day. Then the week after finishing taking the superdrol I took 150mg of test. By the end of the 30 dats I wasa at 230 pounds. The week following the superdrol my strength was going down and my weight began to drop to about 224. I then started the MK-2866 at 10-15mg a day (hard to measure exactly with the dropper I have). I have been on it for about 2 weeks and my weight has crept back up to 230. My strength is not like it was on the superdrol but it has stopped decreasing.

I am now going to stop taking all test and just take the MK-2866 with clomid, HCG, and DAA to see if I can get myself to somewhat normal levels again. I am prescribed 200mg test every 2 weeks and I have been taking that for a while. I would like to see if I can get myself going again with this combo while not loosing any size.

I appreciate the input. please keep us updated.

 

[Bionic]

this might be a very ignorant question but what are the reasons for wanting to stimulate the androgen receptors in the brain?

Bumping for an answer.

EDIT: Looking at the illustration of where Ostarine exerts its effects, it seems that both exo. androgens and Osta stimulate the brain but Osta has no effect on skin and an inhibitory effect on the prostate.

 

[dieselbuilder]

Does anyone think that this compound supresses the HPTA at least a little bit?

The studies were done using 3mg per day on the patients...not 15mg or 25mg.

 

[Human Rocket]

Does anyone think that this compound supresses the HPTA at least a little bit?

The studies were done using 3mg per day on the patients...not 15mg or 25mg.

It's confirmed that estrogen levels will go up while on ostarine alone. Maybe not enough to warrant an AI but estrogen does go up. I think the theory is that ostarine upregulates aromatase.

 

[Ripped Mass]

It's confirmed that estrogen levels will go up while on ostarine alone. Maybe not enough to warrant an AI but estrogen does go up. I think the theory is that ostarine upregulates aromatase.

I usually run aramosin all the way through PCT anyways so this should be beneficial in that regard right?

 

[jdchaffin]

sounds like exemestane would be a fine pairing then.

 

[Osta-gain]

It's confirmed that estrogen levels will go up while on ostarine alone. Maybe not enough to warrant an AI but estrogen does go up. I think the theory is that ostarine upregulates aromatase.

Human Rocket please post where this is confirmed, because i have read probably 90% off all clinical trials on OSTARINE and never read once that it raises estrogen levels..

Maybe you are confused with S4... Yes S4 will raise estrogen but not all SARMS are the same. So please back up your post with a referance... As of every clinical document to date ostarine does not raise estrogen levels..

 

[Osta-gain]

I usually run aramosin all the way through PCT anyways so this should be beneficial in that regard right?

And you can stop taking your aramosin when planned and keep on the ostarine because ostarine does not raise your estrogen level and or affect your hpta function:headbang:

 

[dieselbuilder]

ostarine does not raise your estrogen level and or affect your hpta function:headbang:

Yea maybe you missed my post. You said ask away and I asked whether anyone could say whether or not they were shutdown or had any hpta suppression while at 15mg-25mg per day considering the clinical trials had patients on 3mg per day. So what is the verdict?????