mk-677 mix with juice?

[cashrolling]

I love the mk, but i cant take the nasty aftertaste in my mouth, can i get some orange juice in my mouth and then add the mk, this way i can hold it a few minutes before i swallow. Is this ok or the juice will affect the mk?

 

[sluggy]

According to RS you can just swallow it, so that should help with your issue.

 

[cashrolling]

I don't have time to research, but I heard a while ago that by swallowing it would loose its potency.....im getting confused, please people update me. I try with juice and its perfect to hold in the mouth, also swallowing would be way easier......chime in with ur experience please

 

[johnjuanb1]

I love the mk, but i cant take the nasty aftertaste in my mouth, can i get some orange juice in my mouth and then add the mk, this way i can hold it a few minutes before i swallow. Is this ok or the juice will affect the mk?

I would think swallowing MK-677 in grapefruit juice would make it as potent as taking it sublingually.

 

[cashrolling]

I would think swallowing MK-677 in grapefruit juice would make it as potent as taking it sublingually.

sounds good

 

[Knight9]

I love the mk, but i cant take the nasty aftertaste in my mouth, can i get some orange juice in my mouth and then add the mk, this way i can hold it a few minutes before i swallow. Is this ok or the juice will affect the mk?

You don't need to hold it in your mouth...I'm not sure why everyone buys into this cuz one guy said it.

I would think swallowing MK-677 in grapefruit juice would make it as potent as taking it sublingually.

Why do you insist on saying that it must be taken sublingually? Russianstar clearly stated there is no need for that. Do you have concrete evidence (more than one study or source) stating that it should be held under the tonuge? I do not get this obsession with this procedure and everyone assuming it's THE way.

 

[Giants83]

Mk677 has been shown to have about 60% bioavailabilty(BA). Which is better than most supplements but still falls a bit short. Not really sure if sublingual helps that or not but like JJ said grapefruit juice will help with the BA. Grapefruit juice contains CYP3A4 which is know for increasing the BA of medications and herbs. I take mine with grapefruit juice. And no I don't have any studies that prove grapefruit juice and mk677 work better together but I can post some about its BA if needed. You'll know when it's working. Hope this helps.

 

[ZOFO1973]

Just chase the MK with juice or whatever.

 

[johnjuanb1]

You don't need to hold it in your mouth...I'm not sure why everyone buys into this cuz one guy said it.


Why do you insist on saying that it must be taken sublingually? Russianstar clearly stated there is no need for that. Do you have concrete evidence (more than one study or source) stating that it should be held under the tonuge? I do not get this obsession with this procedure and everyone assuming it's THE way.

Sublinguals with alcohol as the carrier have a faster absorption rate.
Alcohol pulls them into the blood stream much like an intraveneous injection.
Getting a drug right into the blood steam means no destruction of the drug by the stomach acids.
This has been know for decades.

Russianstar also says exogenous HGH doesn't inhibit gh peptides which contradicts every study posted.
Tell me DATBTRUE said this or that and I'll bow down.
Here is a basic study on alcohol used as a sublingual drug carrier:

A study of sublingual absorption. I. Several factors influencing the rate of absorption - Katz - 2006 - Journal of the American Pharmaceutical Association - Wiley Online Library

Abstract
"Solutions of drugs were sublingually administered to anesthetized animals whose esophagus had been ligated and trachea cannulated. This method was devised so that there would be no possibility of the drug being swallowed. As determined by the time for convulsions to appear in anesthetized rats or for death to occur in anesthetized mice, strychnine sulfate in alcohol, strychnine sulfate in water, and strychnine in alcohol were found to be well absorbed sublingually, and in that order, while strychnine suspended in water was not absorbed. The use of the base or the salt and the vehicle employed had a more important effect on sublingual absorption than on oral absorption. Aconitine in alcohol was more rapidly absorbed sublingually than aconitine hydrochloride in water although there was no difference in subcutaneous absorption. Alcoholic solutions of Pentothal® and pentobarbital as well as aqueous solutions of their sodium salts were absorbed sublingually as demonstrated by the increased sleeping time of anesthetized mice. Alcoholic solutions produced the greatest increase. The form of a drug and the vehicle used play an important role in sublingual absorption."

 

[Giants83]

Good to know JJ, I did not know that. Maybe I will go back to sublingual followed by a chaser of grapefruit juice. Taste don't really bother me. I'm dosing a little higher too.

 

[rAJJIN]

For me it started with the IP tabs.
He would say on certain ones to take like that....
Or to crush because the tablet was smashed so tight.

I have not used mk-677
But I have experimented around with it a lot
With cialis and Viagra tabs of all sorts.
Anymore, I just swallow them. No need to leave that nasty
Shit under your tongue IMO hoping to absorb
A tiny bit more.

Now some cases it may be needed??
Doubt I do that anymore myself tho

 

[pesty4077]

MK-677 burns the underneath of your tongue in that alcohol. There has to be a better way.

 

[Giants83]

MK-677 burns the underneath of your tongue in that alcohol. There has to be a better way.

Sure does. Makes any food you eat taste funny. Try with grapefruit juice. That has to increase the BA enough to make it just as effective. I honestly haven't noticed much of difference since switching. I still get numbness in my hands at times and I still want to eat everything in sight.

 

[pesty4077]

Sure does. Makes any food you eat taste funny. Try with grapefruit juice. That has to increase the BA enough to make it just as effective. I honestly haven't noticed much of difference since switching. I still get numbness in my hands at times and I still want to eat everything in sight.

I am going to have to give that a shot. I agree, it screws your taste buds up.

 

[WayBigger]

For me it started with the IP tabs.
He would say on certain ones to take like that....
Or to crush because the tablet was smashed so tight.

I have not used mk-677
But I have experimented around with it a lot
With cialis and Viagra tabs of all sorts.
Anymore, I just swallow them. No need to leave that nasty
Shit under your tongue IMO hoping to absorb
A tiny bit more.

Now some cases it may be needed??
Doubt I do that anymore myself tho

IP tabs is what started the Sublingual

 

[WayBigger]

Would 100% Cranberry have the same affects as grape juice?

 

[johnjuanb1]

Would 100% Cranberry have the same affects as grape juice?

No. It has to be grapefruit juice, not grape juice or any other.
Just be careful not to have any other meds in your stomach at the time of taking grapefruit juice. It effectives the absorption rate of many drugs making some dangerously strong.

 

[johnjuanb1]

For me it started with the IP tabs.
He would say on certain ones to take like that....
Or to crush because the tablet was smashed so tight.

I have not used mk-677
But I have experimented around with it a lot
With cialis and Viagra tabs of all sorts.
Anymore, I just swallow them. No need to leave that nasty
Shit under your tongue IMO hoping to absorb
A tiny bit more.

Now some cases it may be needed??
Doubt I do that anymore myself tho

What got me into the whole sublingual kick was many years ago I held Thai anadrol under mg tongue for 15 minutes then went to the gym. The pump was like nothing I had ever felt. So, I had my friend try it and he experienced the same thing.
Then, at some point in time, I read alcohol pulls drugs right into your blood steam, which meant less drug sits in your stomach while trying to absorb. This just makes sense that a higher percentage of the drug will be utilized.

But, MK-677 was created for oral use. Even though the absorption rate may be lessened when taken orally, it obviously works well based on the studies.

 

[MikeCrisp]

You don't need to hold it in your mouth...I'm not sure why everyone buys into this cuz one guy said it.


Why do you insist on saying that it must be taken sublingually? Russianstar clearly stated there is no need for that. Do you have concrete evidence (more than one study or source) stating that it should be held under the tonuge? I do not get this obsession with this procedure and everyone assuming it's THE way.

I hold it under the tongue in split back to back doses. I figure why take a chance, right? No negative to doing it this way, so I figure why not

 

[Knight9]

I hold it under the tongue in split back to back doses. I figure why take a chance, right? No negative to doing it this way, so I figure why not

I think consulting with those smarter than you will help you learn. You're doing some ocd stuff that doesn't necessarily make any sense.