Mots-C anyone tried it ?

[Josefein421]

I have tried 2mg and noticed a little. 4mg was definitely more energy/endurance but a little more crash/comedown. 6mg I did once but was also combined with 1.5mg SLUPP and the effect was great but the crash was actually really crappy. I had to lay down a little bit. This is injected once a day before training or cardio if an off day.

I guess not surprising more works better but also has worse side effects. Also interesting how they affect people so different. I just saw JP say he takes 1mg MOTS and 5mg SS31 and feels like he can train 30hrs. Granted he has a peptide company but then he is also saying he's using less than most people here so that cant be a business plug...

I think I will also cycle off of MOTS and SLUPP more frequently... maybe 2 on/1 off or something if I run it a while.

 

[Sully1234]

All this is relatively new so we are all lab rats.
Mots-C is easier to get than SS31 now. I think based on reading that it is superior for energy, I took a week of it at 2mg a day and it was pretty potent. I will probably hit it after the SS31 at 2mg on off days only. I feel SS31 is great for the heart and kidneys. It's odd but I noticed better more restful sleep on it so far less aches and pains and increases daily energy and cognition. I am taking 3 mg in the am.

Sorry - which are you saying is superior for energy? Mots or SS?

 

[Massive G]

Sorry - which are you saying is superior for energy? Mots or SS?

I noticed energy from ss31 as well but mots-c was like a super charger.

 

[luki7788]

All this is relatively new so we are all lab rats.
Mots-C is easier to get than SS31 now. I think based on reading that it is superior for energy, I took a week of it at 2mg a day and it was pretty potent. I will probably hit it after the SS31 at 2mg on off days only. I feel SS31 is great for the heart and kidneys. It's odd but I noticed better more restful sleep on it so far less aches and pains and increases daily energy and cognition. I am taking 3 mg in the am.

Everyone can say what they want, believe it or not, but I’ll just share my experience. My cystatin C and GGT, related to kidney and liver function, wouldn’t drop below a certain level for about nine/ten months. They were close to the normal range, but still slightly above, even though everything else was already fine.

Only after I introduced retatrutide and MOTS-c did those markers finally return to normal. And not just barely, but right into the middle of the range.
Maybe it was because of that, maybe not. But for me, the timing is clear. I’ll keep using them.

 

[Sully1234]

Everyone can say what they want, believe it or not, but I’ll just share my experience. My cystatin C and GGT, related to kidney and liver function, wouldn’t drop below a certain level for about nine/ten months. They were close to the normal range, but still slightly above, even though everything else was already fine.

Only after I introduced retatrutide and MOTS-c did those markers finally return to normal. And not just barely, but right into the middle of the range.
Maybe it was because of that, maybe not. But for me, the timing is clear. I’ll keep using them.

Very interesting.

Question - when you were taking large doses 10mg or so MOTS-C did you notice any energy from it?

I recall the effects on your blood glucose but didnt see you mention along those lines.

 

[luki7788]

Very interesting.

Question - when you were taking large doses 10mg or so MOTS-C did you notice any energy from it?

I recall the effects on your blood glucose but didnt see you mention along those lines.

Honestly, I don’t feel any increase in energy right after the MOTS-c injection. In general, I just feel a bit better overall, healthier maybe. It’s hard to describe.

But the way some people describe an immediate energy boost after the injection, I don’t feel that at all. To me, it sounds more like a placebo effect. But maybe I’m wrong, or maybe I’m just resistant, haha.

 

[Bashmannutter]

Personally for me, MOTs-C has been a game changer for blood sugar management when trying to push my GH higher. Originally when I got up to 6iu from originally peak dose of 4iu, my fasted BG went south very fast, creeping over 6.

After introudcing MOTs-C, 1mg every morning, my fasted BG doens't peak over 5 and on average around 4.7 with 2hr post prandial being the same. I also notice a decent energy boast from it. Very impressed. Im now for first time using 7iu GH.



I have also kept up with fasted cardio and steps Religiously at least 12k day.

 

[whacked]

Honestly, I don’t feel any increase in energy right after the MOTS-c injection. In general, I just feel a bit better overall, healthier maybe. It’s hard to describe.

But the way some people describe an immediate energy boost after the injection, I don’t feel that at all.

Similar experience here with one additional benefit…

I don’t well with a lot of carbs; despite having an excellent fasting insulin assay (odd, yes).

When using MOTS-C, I don’t feel the post-carb malaise - which mechanistically, makes sense.

Dose is 3mg/day (@ 3 days on/1 day off).

 

[Sully1234]

This week I'm out of town 10 days. Brought a 10mg MOTS-C and 30mg SS-31.

Planning on doing 1mg MOTS-C and 3mg SS-31 per day.

There's no SS-31 thread so figured I'd put info in here.

Took my first shot about 2 hours ago. Didn't sleep well and woke up with a little sleep apnea head ache - can feel blood flow in head when I sleep in a bad position.

Feel good right now physically energy wise and cognitively have a good boost, mental clarity.

Really beneficial to me for someone who almost has always had brain fog since having Lyme's/thyroid issues/chronic fatigue for years.

 

[Sectør]

This week I'm out of town 10 days. Brought a 10mg MOTS-C and 30mg SS-31.

Planning on doing 1mg MOTS-C and 3mg SS-31 per day.

There's no SS-31 thread so figured I'd put info in here.

Took my first shot about 2 hours ago. Didn't sleep well and woke up with a little sleep apnea head ache - can feel blood flow in head when I sleep in a bad position.

Feel good right now physically energy wise and cognitively have a good boost, mental clarity.

Really beneficial to me for someone who almost has always had brain fog since having Lyme's/thyroid issues/chronic fatigue for years.

Most people usually run a compound for weeks or months then give us an update (and most of their variables are controlled)

From what I’ve seen with your posts you’re constantly changing dosages and compounds everyday then coming back a few hours later to give us “feels reports”

like you saying you took mots-c then experienced visual changes/distortions walking your dog a few hours later, or taking your first dose of ss-31 then giving us a 2 hour update.

Maybe these kinds of things would be better in a log rather than clogging up a main summary style thread? No offense but I’m just not sure how reliable any of your statements are when you’re constantly changing variables in every post I’ve seen. Seems like you’re just placeboing yourself out then coming back with weird anecdotes hours later

 

[Sully1234]

Most people usually run a compound for weeks or months then give us an update (and most of their variables are controlled)

From what I’ve seen with your posts you’re constantly changing dosages and compounds everyday then coming back a few hours later to give us “feels reports”

like you saying you took mots-c then experienced visual changes/distortions walking your dog a few hours later, or taking your first dose of ss-31 then giving us a 2 hour update.

Maybe these kinds of things would be better in a log rather than clogging up a main summary style thread? No offense but I’m just not sure how reliable any of your statements are when you’re constantly changing variables in every post I’ve seen. Seems like you’re just placeboing yourself out then coming back with weird anecdotes hours later

If you look at the thread there are tons of people reporting acute effects (anecdotal) and also Luki measuring blood glucose long term.

I'm not really doing anything much different than what 90% of people on this board do, no?

Over the years I've tried dozens of different protocols, supplements whatever for my chronic fatigue. Was I excited to try these after what others mentioned, sure.

As far as placebo goes, the other day I accidentally pinned 3iu of GH instead of MOTS-C since the vials are not labeled. Grabbed the wrong tupperware and didnt look at my note card inside.

I didnt get my "visual distortions" and energy. I got tired and didnt realize until I went to take my GH that night.

Also, this is the second time you are exaggerating what I actually said to I guess discredit what I said? Even when someone else replied and said they notice something similar. I said colors seemed brighter and I felt good like a little euphoria.

When you have been low energy for the better part of 15 years, yeah some energy might feel a little euphoric.

I have also mentioned Lyme's multiple times, not sure if you're familiar since it's mostly only ticks in the North East that carry it. I brought up Lyme's/fatigue multiple times intentionally because it is not the status quo.

Per NIH "Lyme disease causes mitochondrial dysfunction by damaging the cell's energy-producing organelles, leading to chronic fatigue, brain fog, and muscle weakness. The bacterium Borrelia burgdorferi induces oxidative stress and inflammation, which damage mitochondrial DNA and reduce ATP production. This dysfunction is often a key factor in lingering symptoms (PTLDS)."

I think given the science behind these two peptides I'm a pretty good candidate to benefit from them.

This is a discussion board... You *seem* to be the only one taking issue with my posts and I haven't gotten any other feed back from other posters or moderators that I'm dumbing the board down.

Anyway, I thought I was just posting interesting (to me) things that I've noticed from these.

If the consensus is "no thanks" I'm happy not to share, otherwise you are free block me

 

[Sectør]

If you look at the thread there are tons of people reporting acute effects (anecdotal) and also Luki measuring blood glucose long term.

I'm not really doing anything much different than what 90% of people on this board do, no?

Over the years I've tried dozens of different protocols, supplements whatever for my chronic fatigue. Was I excited to try these after what others mentioned, sure.

As far as placebo goes, the other day I accidentally pinned 3iu of GH instead of MOTS-C since the vials are not labeled. Grabbed the wrong tupperware and didnt look at my note card inside.

I didnt get my "visual distortions" and energy. I got tired and didnt realize until I went to take my GH that night.

Also, this is the second time you are exaggerating what I actually said to I guess discredit what I said? Even when someone else replied and said they notice something similar. I said colors seemed brighter and I felt good like a little euphoria.

When you have been low energy for the better part of 15 years, yeah some energy might feel a little euphoric.

I have also mentioned Lyme's multiple times, not sure if you're familiar since it's mostly only ticks in the North East that carry it. I brought up Lyme's/fatigue multiple times intentionally because it is not the status quo.

Per NIH "Lyme disease causes mitochondrial dysfunction by damaging the cell's energy-producing organelles, leading to chronic fatigue, brain fog, and muscle weakness. The bacterium Borrelia burgdorferi induces oxidative stress and inflammation, which damage mitochondrial DNA and reduce ATP production. This dysfunction is often a key factor in lingering symptoms (PTLDS)."

I think given the science behind these two peptides I'm a pretty good candidate to benefit from them.

This is a discussion board... You *seem* to be the only one taking issue with my posts and I haven't gotten any other feed back from other posters or moderators that I'm dumbing the board down.

Anyway, I thought I was just posting interesting (to me) things that I've noticed from these.

If the consensus is "no thanks" I'm happy not to share, otherwise you are free block me

Not taking issues with your posts. The main point was to maybe give it more than 2 hours before forming an opinion on a compound. It was simply a suggestion, which you’re free to ignore.

“I pinned this 2 hours ago and here’s what I think about the compound” is pretty much a useless take for anyone referencing this thread for information.

Post whatever you want though I genuinely don’t care. Was just offering you a way to provide better detail (by creating a log), then you could just link your log to the master thread that way people have something to reference if they want hourly feels reports

 

[Sully1234]

Not taking issues with your posts. The main point was to maybe give it more than 2 hours before forming an opinion on a compound. It was simply a suggestion, which you’re free to ignore.

“I pinned this 2 hours ago and here’s what I think about the compound” is pretty much a useless take for anyone referencing this thread for information.

Post whatever you want though I genuinely don’t care. Was just offering you a way to provide better detail (by creating a log), then you could just link your log to the master thread that way people have something to reference if they want hourly feels reports

Okay, well again you're taking what I said and exaggerating/changing it. In bold above.

That is not what I said.

I said I woke up feeling shitty (insinuating also tired from sleep apnea) and then within two hours of pinning I felt good. Pointing out because for me that's not normal.

Short term.

I never made any broad conclusion. I said what I felt, that's all. Because it was very different from my "normal".

Personally, the reason I started looking into these was because the acute effects reported a few hours later in this thread. So that benefitted me.

Anyway, point taken - very possible my posts here have not had any use to anyone. Fair enough

 

[Poppapump49]

Honestly, I don’t feel any increase in energy right after the MOTS-c injection. In general, I just feel a bit better overall, healthier maybe. It’s hard to describe.

But the way some people describe an immediate energy boost after the injection, I don’t feel that at all. To me, it sounds more like a placebo effect. But maybe I’m wrong, or maybe I’m just resistant, haha.

Were you just using the Mots c at 1mg

 

[luki7788]

Were you just using the Mots c at 1mg

sorry man but I don't understand your question lol

 

[whacked]

To all the Dr Trevor haters - he is vindicated here (in link). Lol

He is an abrasive egomanic.

However, to his credit; he was pretty much the only one screaming MOTS-C first (or concurrently) then SS-31 for over a year; and got a lot of flack for it.

Ps. Approximately 11 minutes in, this guy discusses the lack of a requirement for cycling due to receptor desensitization, although it still seems to be prudent.

 

[Ranchhand]

To all the Dr Trevor haters - he is vindicated here (in link). Lol

He is an abrasive egomanic.

However, to his credit; he was pretty much the only one screaming MOTS-C first (or concurrently) then SS-31 for over a year; and got a lot of flack for it.

LOL I was just getting ready to post up this clip. You beat me to it.

 

[whacked]

LOL I was just getting ready to post up this clip. You beat me to it.

lol

 

[Massive G]

I am doing 3 mgs Mots-C am and 3 mgs SS31 pm

Feel absolutely fantastic.

 

[Splitzz]

I am doing 3 mgs Mots-C am and 3 mgs SS31 pm

Feel absolutely fantastic.

Did the ss31 make a big difference when stacked with Mots-c?