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Mots-C anyone tried it ?

Yes - after the injection there is a slight burning sensation for a few minutes, but it is so slight that I don't even bother with it.
I meant more of a permanent thing, that lasts all day. It feels like very sensitive sunburn down my arms and my whole back
 
I meant more of a permanent thing, that lasts all day. It feels like very sensitive sunburn down my arms and my whole back
Maybe you’re just reacting to some filler used in the peptide, not to MOTS-C itself. That could explain the effect you’re describing. Hard to say.
 
Also it’s strange that MOTS-C caused sleep problems for you, but SLU didn’t.

In theory, it should be the opposite. MOTS-C doesn’t directly affect metabolism, while SLU increases mitochondrial activity not just optimizes it, but really pushes it higher.
So that means faster metabolism, and that can actually cause sleep issues. A lot of people report worse sleep on SL-PPP332.

So it’s a bit strange. But maybe it’s just an individual reaction - hard to say.

Oh Im sure SLU would have. By the time I introduced it, my sleep had already been fucked for 2 weeks. It wasnt till I went through all my checkins and logs to see what could be the culprit was when I found that the only thing I added and only change made was adding MOTs-C 3 weeks prior.

I would of caught it earlier but like you say, I would have never of considered that it would be an issue. Absolustely everything else I was doing I have used and done in the past with no issues. I even reduced my GH to half to see if that was the issue, but GH has never been disrupting my sleep like it has been the last 2 weeks.

I will revisit the MOTs-C at some point, perhaps trying a different dose shcedule.
 
Are you cycling Mots or taking it long term? I'm talking about a dose of 1-2mg per day.
 
Maybe you’re just reacting to some filler used in the peptide, not to MOTS-C itself. That could explain the effect you’re describing. Hard to say.
That did cross my mind, and in which case I’ll probably discontinue using it as who knows what it actually is.
 
Been on mots for about 7 weeks now. It pairs great with reta. Lost about 20 pounds already from mid Feb to today
 
And how is it that mots-c should be used for a few weeks 4-6 and a break. Will year-round use with daily doses of 1 mg be good? However, should we take breaks
 
And how is it that mots-c should be used for a few weeks 4-6 and a break. Will year-round use with daily doses of 1 mg be good? However, should we take breaks
Personally, I don’t think you need to take a break from MOTS-C.
If you understand how it works it stabilizes mitochondria function. It does not speed it up like SLU-PP332. SLU pushes mitochondria to max work, so in my opinion it’s not good to use all year, because after some time it can have negative effect.

MOTS-C is different it helps mitochondria work in optimal way. So if you find good dose for yourself and you don’t have side effects, I think you can use it all year.
Of course, if someone wants to take a break for few weeks, no problem.

Personally, I plan to use it most of the year. I will only take breaks maybe once or twice per year, for 3–4 weeks.
In that time I will use SS-31 to help repair mitochondria. I will use it after periods when I push harder, like something like small prep when mitochondria work more because of things like SLU, fat burners, clenbuterol or yohimbine.
After that I use SS-31 for 3–4 weeks to recover mitochondria. Then I go back to MOTS-C to stabilize and optimize them for rest of the year.

This is just my theory and idea. I will try and see how it works. Maybe in 1–2 years I will change my opinion.
This is all still experimental, we are testing on ourselves and we don’t know exactly how it will work.
 
All this is relatively new so we are all lab rats.
Mots-C is easier to get than SS31 now. I think based on reading that it is superior for energy, I took a week of it at 2mg a day and it was pretty potent. I will probably hit it after the SS31 at 2mg on off days only. I feel SS31 is great for the heart and kidneys. It's odd but I noticed better more restful sleep on it so far less aches and pains and increases daily energy and cognition. I am taking 3 mg in the am.
Better sleep for sure for SS-31. Morning and night. Waking up feeling refreshed as well.
 
Personally, I don’t think you need to take a break from MOTS-C.
If you understand how it works it stabilizes mitochondria function. It does not speed it up like SLU-PP332. SLU pushes mitochondria to max work, so in my opinion it’s not good to use all year, because after some time it can have negative effect.

MOTS-C is different it helps mitochondria work in optimal way. So if you find good dose for yourself and you don’t have side effects, I think you can use it all year.
Of course, if someone wants to take a break for few weeks, no problem.

Personally, I plan to use it most of the year. I will only take breaks maybe once or twice per year, for 3–4 weeks.
In that time I will use SS-31 to help repair mitochondria. I will use it after periods when I push harder, like something like small prep when mitochondria work more because of things like SLU, fat burners, clenbuterol or yohimbine.
After that I use SS-31 for 3–4 weeks to recover mitochondria. Then I go back to MOTS-C to stabilize and optimize them for rest of the year.

This is just my theory and idea. I will try and see how it works. Maybe in 1–2 years I will change my opinion.
This is all still experimental, we are testing on ourselves and we don’t know exactly how it will work.
Exactly how I have been doing it. MOTS-C on its own for as long as I like. Add SLU when I want to kick things up and then when I feel it’s necessary I drop it. Continue with the MOTS-C add SS-31 run together for a week and then drop the MOTS-C and let the SS-31 go to work on its own to clean things up for 6-8 weeks. Then I repeat the process.
 
Personally, I don’t think you need to take a break from MOTS-C.
If you understand how it works it stabilizes mitochondria function. It does not speed it up like SLU-PP332. SLU pushes mitochondria to max work, so in my opinion it’s not good to use all year, because after some time it can have negative effect.

MOTS-C is different it helps mitochondria work in optimal way. So if you find good dose for yourself and you don’t have side effects, I think you can use it all year.
Of course, if someone wants to take a break for few weeks, no problem.

Personally, I plan to use it most of the year. I will only take breaks maybe once or twice per year, for 3–4 weeks.
In that time I will use SS-31 to help repair mitochondria. I will use it after periods when I push harder, like something like small prep when mitochondria work more because of things like SLU, fat burners, clenbuterol or yohimbine.
After that I use SS-31 for 3–4 weeks to recover mitochondria. Then I go back to MOTS-C to stabilize and optimize them for rest of the year.

This is just my theory and idea. I will try and see how it works. Maybe in 1–2 years I will change my opinion.
This is all still experimental, we are testing on ourselves and we don’t know exactly how it will work.
Great point, someone with clout needed to say it so people will listen. Thanks Luki 👍

I'll add, maintenance doses of MOTS-C year round. Not supraphysiological doses to burn off as much fat as possible.

Luki & Baldnazi throwing out the finer points with how to use Mots-C, SLU and SS-31 together.
 
I used mots C for the last 6ish? Weeks of this prep. The first half was set up with ss31. I’m not sure how much it did because there’s a fair amount of stuff in play. I used 1.5-2mg daily fasted. I got respectably lean very easily and then the last part was pretty brutal just like it’d be any other year. From 2.5 or so weeks out my energy was pretty much in the toilet regardless.

Overall no negatives, not dramatically different from last year not using it. Maybe a little bit better energy longer or smoother fat loss but definitely not blown away like it would be adding clen or something like that. This prep I did not use clen at all which may have helped with sleep longer also. If it’s in the budget I’d say throw it in if not you’ll get the same result without it imo.

I plan on using it in phases of the offseason too for insulin sensitivity so we’ll see how that plays out over the next year or so.
 
Another great thread full of cracking info.

I have a question which hoping someone could advise on please:

I started Reta on Mon 27th April, went 0.5mg, and then 0.5mg again on Thursday 30th April, to get to 1mg for the first week.

I upped that on Mon 4th May, 1mg and then 1mg again today, so nudging to 2mg for this week.

I have been reading about MOTS-C and also SLU but I think SLU seems a bit more hassle in terms of constitution so am tempted to get some MOTS-C and add that to the mix alongside the Reta.

Have you guys seen good results when using Reta & MOTS-C together? What sort of dose would you introduce the MOTS-C at? Thanks all!
 
Thank you for posting.

Cliff notes on dosing for anyone too lazy to watch these videos like I usually am:

SS-31
4mg daily showed same benefits as 40mg daily in a study
3-4mg likely max effective dose
Speakers optimization dose is generally 2mg per day
Save your money

MOTS-C
Dosing 3x per week maintained all measurable benefits
5-15mg per week
Speaker recommends 10mg spread through week
Peptide has short half life but works through gene expression so works after peptide has cleared

Would be nice is there was a similar MOTS-c study comparing say 3mg per day vs 30mg

@Kauto_star 10-11 minute vid on post #416 in this thread. Here were my crappy notes above.

For cardio or weights, MOTS-C an hour pre seems to give a good boost.

SLU can be tricky... If I take 1g oral SLU 915 pre its made me very tired. Other guys take a couple mg Injectable SLU 332 and get tons of energy all day.
 
@Kauto_star 10-11 minute vid on post #416 in this thread. Here were my crappy notes above.

For cardio or weights, MOTS-C an hour pre seems to give a good boost.

SLU can be tricky... If I take 1g oral SLU 915 pre its made me very tired. Other guys take a couple mg Injectable SLU 332 and get tons of energy all day.
Thanks buddy! Appreciate that!

How much MOTS-C did you run? Other than energy boost did you get any body composition benefits?

Cheers.
 
Thanks buddy! Appreciate that!

How much MOTS-C did you run? Other than energy boost did you get any body composition benefits?

Cheers.

Can't speak to that honestly. I've been toying with Reta, Tirz, Mots-C and SS-31 here or there.

Very little consistency in day to day life (new job, new house reno, travel for work etc) so my workouts have just been whatever I can do to stay active whenever I can.

I will say after dealing with chronic fatigue for years I'm pretty sensitive to placebos, the acute effects from MOTS-C are great.

Would happily sub out a stimulant based pre workout for 2-3mg MOTS-C any time.

I'm also a bit of an outlier since my CF was from a Lyme infection so take that for what it's worth.
 
Can't speak to that honestly. I've been toying with Reta, Tirz, Mots-C and SS-31 here or there.

Very little consistency in day to day life (new job, new house reno, travel for work etc) so my workouts have just been whatever I can do to stay active whenever I can.

I will say after dealing with chronic fatigue for years I'm pretty sensitive to placebos, the acute effects from MOTS-C are great.

Would happily sub out a stimulant based pre workout for 2-3mg MOTS-C any time.

I'm also a bit of an outlier since my CF was from a Lyme infection so take that for what it's worth.

Ahhhhh ok interesting! Thanks buddy, appreciate the comments. Sounds like you have had a good experience with it mind.
 
Ahhhhh ok interesting! Thanks buddy, appreciate the comments. Sounds like you have had a good experience with it mind.

To say the least, yes. Since adding in MOTS-C and SS-31 I definitely have much more energy all around. I dont get mid morning or mid afternoon slumps any more.

These two I've been consistent with and they have significantly helped with daily energy.

EDIT: I would also get acute effects but after a few weeks of these I seem to notice the best beenfits.
 
To say the least, yes. Since adding in MOTS-C and SS-31 I definitely have much more energy all around. I dont get mid morning or mid afternoon slumps any more.

These two I've been consistent with and they have significantly helped with daily energy.

EDIT: I would also get acute effects but after a few weeks of these I seem to notice the best beenfits.

Excellent! Good on you bud!
 

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