NAC

[deadliftsquates]

I know we are about muscle here but does anyone have experience / knowledge of N-Acetylcysteine and addiction treatment? And experiences with brands of NAC and is there an injectable version? Thanks guys.

 

[aphextwin]

I use NAC every single day, but not for addiction purposes. I use Now and Jarrow's brands.

 

[icedemon]

I use NOW, but for liver support. There is injectable versions out there. You'd have to PM me if you want to know where.

 

[swim15]

I’ve found it extremely effective for addiction treatment. I deal with ADD and a lot of impulsivity issues but it definitely attenuates all of that significantly

 

[liv2pb]

Gear is the best cure for addiction....but then you develop a new addiction....lol

But to answer your question, NAC won't do much if anything for addiction.

 

[nothuman]

I know we are about muscle here but does anyone have experience / knowledge of N-Acetylcysteine and addiction treatment? And experiences with brands of NAC and is there an injectable version? Thanks guys.

The effect is mild according to examine.com. Only 1 arrow for that category.

 

[jeroendebleser]

Addiction to what exactly?

 

[deadliftsquates]

opiods

 

[blkhrt_jordan]

Dont know about proven science but plenty anecdotal reports that it calms the obsessive and compulsive aspects of drug seeking. I took it when quitting opioids and i think it helped, among other things. I still take it now for general health and wellness and for some specific issues. 1.2g a day, i also take lipoic acid and coq10 as part of a mitochondrial health stack, and it really helps offset some of the damage from hypoxia.

If you are recovering from opioids look into LDN, it really helped me feel more normal sooner. It was almost like a trigger switch from reverting my fucked up addict brain back to a sense of normalacy.

If you take NAC get a brand that doesnt smell strongly of sulfur and keep it in the fridge. Contrary to popular online opinion, strong sulfur smelling nac isnt stronger, its more degraded

 

[aphextwin]

Not to take this thread in the wrong direction, but I take 1,000-1,2000 mg daily with Vitamin C. I use it bc it's a great antioxidant and for liver health. Also, I noticed my asthma improved after using it. I'm wondering if it's really necessary to consume Vitamin C at the same time as NAC?

 

[nothuman]

Not to take this thread in the wrong direction, but I take 1,000-1,2000 mg daily with Vitamin C. I use it bc it's a great antioxidant and for liver health. Also, I noticed my asthma improved after using it. I'm wondering if it's really necessary to consume Vitamin C at the same time as NAC?

I'm not sure of the synergy between those two but I do know NAC and glycine showed great benefits for diastolic function of hearts in rats (NAC alone didn't)

 

[aphextwin]

I'm not sure of the synergy between those two but I do know NAC and glycine showed great benefits for diastolic function of hearts in rats (NAC alone didn't)

Do you recall to dosage for the two?

 

[TheOtherOne55]

If we're strictly talking about opiod addiction, why not go with Kratom??

I mean that's exactly WHY there's so much hype with kratom. It's ridiculously effective at allowing heavy users to taper off opiods.

 

[nothuman]

Do you recall to dosage for the two?

Here is the abstract
https://academic.oup.com/biomedgero...act/73/9/1167/4925804?redirectedFrom=fulltext

Doesn't say dose there but I wouldn't know how to convert rat to human doses anyway

 

[aphextwin]

You are a walking encyclopedia. Thanks

 

[Stewie]

Here is the abstract
https://academic.oup.com/biomedgero...act/73/9/1167/4925804?redirectedFrom=fulltext

Doesn't say dose there but I wouldn't know how to convert rat to human doses anyway

The HED (human equivalent dose) at the given dosage would roughly be 23.5 grams of each--NAC/Glycine. And they're mouse models, not rat using the factor of 6/37 formula.

irradiated chow + 1.6 g/kg
N-acetyl-L-cysteine (NAC group, n = 6) or irradiated chow + 1.6 g/
kg N-acetyl-L-cysteine +1.6 g/kg glycine (NAC+Gly group, n = 17)

 

[nothuman]

The HED (human equivalent dose) at the given dosage would roughly be 23.5 grams of each--NAC/Glycine. And they're mouse models, not rat using the factor of 6/37 formula.

Yikes that's a lot

 

[Stewie]

Yikes that's a lot

Actually I used the incorrect inter-species dose extrapolation on one type of configuration. For the inter-species dose of a mouse is determined by the factor of 3, not 6 (rat is a factor of 6, mouse is 3) that I erroneously figured.

Nevertheless, the dosage would be roughly 12 grams of each for a 90.718kg (200lb) individual.

 

[nothuman]

Actually I used the incorrect inter-species dose extrapolation on one type of configuration. For the inter-species dose of a mouse is determined by the factor of 3, not 6 (rat is a factor of 6, mouse is 3) that I erroneously figured.

Nevertheless, the dosage would be roughly 12 grams of each for a 90.718kg (200lb) individual.

Even so, 12g of Nac is 20 pills that are 600mg, which is pretty much a crazy amount

 

[Smack]

Even so, 12g of Nac is 20 pills that are 600mg, which is pretty much a crazy amount

It comes in powder form too. Lmk if you need a source