New Drugs on the Horizon?

[JustinWK]

Yea so high interval confidence the cope seethe you will yet see come next years will be unfathomable ignorants to continue malding yelling at clouds nothing new under the sun cheers

I want to be hopeful but remain doubtful monoclonal antibodies will ever be a feasible market anytime soon on the grey market.

 

[KingOfSushi]

I think it's the people who already take 17 drugs hoping for a 1 percent advantage who are interested in them.

To add, I’d say this is the SMALLEST fraction of the GLP1 users. I’m sure plenty aren’t even in the gym to begin with, or if they are it’s hardly a focus for them on the level of an actual bodybuilder.

 

[Simon90]

To add, I’d say this is the SMALLEST fraction of the GLP1 users. I’m sure plenty aren’t even in the gym to begin with, or if they are it’s hardly a focus for them on the level of an actual bodybuilder.

This. Most of my office are on them. They couldn't even tell you what the inside of the gym looks like!

 

[KingOfSushi]

That and 'muscle' maturity etc still has to be built but your standard 'holy gains' from a first Tren cycle etc is foreseeable in the near future on advancements such as the above.

Holy gains is 2lbs of muscle loss in a cut?

 

[qbkilla]

Come to SFL, where EVERYONE from your gym rat, competitors, to soccer moms, to fresh out of high school teens/young adults who were fat all through high school, to even doctors and people at these “wellness/TRT clinics” etc etc..

I know at least a half dozen people on it right now who don’t even workout.. As a matter of fact, I know 2-3 who not only don’t workout, but they don’t even eat healthy food (I can’t comment on the others because I haven’t seen what they eat).. They’re just eating less ice cream, chocolate, chips, cookies, pasta (stuff I’ve literally witnessed them eating) etc.. Fat/Carbs still make up the majority of their macros, despite their being less of it than before because of the obvious appetite suppression, and not a single micro nutrient in sight

I’d imagine there’s A LOT of people doing the same thing because GLP’s might solve an over appetite issue, but not a “unhealthy life habits” issue..

I’d also imagine there will be some serious consequences of such actions that we’ll be hearing about in the coming years as this becomes more popular..

Least shocking thing I've read in a while. Yet they all claim the glp " changed their habits!"

 

[URODA]

Least shocking thing I've read in a while. Yet they all claim the glp " changed their habits!"

Yeah seriously your ignorace and lack of intellectual curiosity show clearly those drugs literally work one way by rewiring your addiction habits

 

[qbkilla]

Yeah seriously your ignorace and lack of intellectual curiosity show clearly those drugs literally work one way by rewiring your addiction habits

Did you read his post? Doesn't sound like the glp users are eating cage free eggs and avocado and running the trails. So now eating junk food and sitting on the couch is "addiction " ?

 

[URODA]

Did you read his post? Doesn't sound like the glp users are eating cage free eggs and avocado and running the trails. So now eating junk food and sitting on the couch is "addiction " ?

Yeah so your reading comprehension makes “2-3” yet equal to everyone cheers

 

[derzwerg]

Did you read his post? Doesn't sound like the glp users are eating cage free eggs and avocado and running the trails. So now eating junk food and sitting on the couch is "addiction " ?

There's a pretty strong argument for junk food actually being addictive. It's hyper palatable and engineered to keep one coming back for more.

I can bake some pretty delicious, decadent cookies and be good after a few. Yet, I could absolutely crush a box of Oreos without issue... That's by design.

Foods packed full of salt, sugar and fat cause a rapid rise of dopamine in the brain's reward center, much the same as nicotine or cocaine... Not of the same magnitude of cocaine but it can be on par with nicotine.

Then there's the availability. If you need a "quick fix" there's probably something in your cupboard or at the corner store a block away. In polls, some people have reported quitting junk food to be more difficult than cigarettes or alcohol.

I, coincidentally, have been doing some reading about the food industry lately lol but I do believe processed foods are addictive. And, like other substances, that addiction varies from one person to another.

Some use glp1s and continue to eat junk, sure. But for some, a glp will help break that habit, and others as well. There are human studies underway looking at semaglutide and liraglutide as treatment options for alcohol use disorder. Also animal studies for nicotine, cocaine, amphetamines, heroin... And I've seen plenty of people say they started a glp to lose weight and ended up quitting smoking or something similar.

They seem to reduce dopaminergic signaling. And I definitely feel that, myself. Even a very low dose takes away cravings and kinda removes the reward if I do indulge. I get on great with tirzepatide but retatrutide gives me restless legs pretty bad... Another indicator of reduced dopaminergic signaling.

So, in short, I would argue that junk food is addictive, yes.

Maybe everyone should just toughen up and find some will power? Or perhaps some are just more prone to addiction and a glp levels the playing field? Maybe the way you feel, normally, is how someone feels with a glp turning things down a bit...

 

[qbkilla]

Yeah so your reading comprehension makes “2-3” yet equal to everyone cheers

Well if glp's change behavior rather than just make people feel like shit when they indulge, all glp users should be coming off them pretty quicky...because they have learnered new behavior. Good to know that people only use them for a short period to become models of health and physical activity cheers

 

[KingOfSushi]

Well if glp's change behavior rather than just make people feel like shit when they indulge, all glp users should be coming off them pretty quicky...because they have learnered new behavior. Good to know that people only use them for a short period to become models of health and physical activity cheers

Do you come off your antidepressant drugs if you start feeling better when taking them

 

[finephysique]

I

@qbkilla

About 12% of Americans have tried a GLP based on polls that have been done. TBH I would argue it’s much higher than that.

A lot of people use GLP’s and don’t want others to know. It’s almost become a shame thing. Trade one issue for the other- shamed if you’re fat or shamed if you use a GLP to not be fat. lol

there was about a 20 year period where large numbers of bodybuilders refused to admit they used insulin, and would always deflect with “no way bro that will make you diabetic” or ‘I had an aunt who was diabetic so I won’t mess with that stuff”. Heard those things at so many seminars and knew they were mostly lying, it was the same on many of the forums. I think these glp meds will soon just be part of the stack for most if not already part of it if the truth were spoken.

 

[kadafi2]

I

there was about a 20 year period where large numbers of bodybuilders refused to admit they used insulin, and would always deflect with “no way bro that will make you diabetic” or ‘I had an aunt who was diabetic so I won’t mess with that stuff”. Heard those things at so many seminars and knew they were mostly lying, it was the same on many of the forums. I think these glp meds will soon just be part of the stack for most if not already part of it if the truth were spoken.

It will certainly be easier for a bodybuilder to admit to taking GLP1 than to SEO, DNP, or high doses of GH.

There's a pretty strong argument for junk food actually being addictive. It's hyper palatable and engineered to keep one coming back for more.

I can bake some pretty delicious, decadent cookies and be good after a few. Yet, I could absolutely crush a box of Oreos without issue... That's by design.

Foods packed full of salt, sugar and fat cause a rapid rise of dopamine in the brain's reward center, much the same as nicotine or cocaine... Not of the same magnitude of cocaine but it can be on par with nicotine.

Then there's the availability. If you need a "quick fix" there's probably something in your cupboard or at the corner store a block away. In polls, some people have reported quitting junk food to be more difficult than cigarettes or alcohol.

I, coincidentally, have been doing some reading about the food industry lately lol but I do believe processed foods are addictive. And, like other substances, that addiction varies from one person to another.

Some use glp1s and continue to eat junk, sure. But for some, a glp will help break that habit, and others as well. There are human studies underway looking at semaglutide and liraglutide as treatment options for alcohol use disorder. Also animal studies for nicotine, cocaine, amphetamines, heroin... And I've seen plenty of people say they started a glp to lose weight and ended up quitting smoking or something similar.

They seem to reduce dopaminergic signaling. And I definitely feel that, myself. Even a very low dose takes away cravings and kinda removes the reward if I do indulge. I get on great with tirzepatide but retatrutide gives me restless legs pretty bad... Another indicator of reduced dopaminergic signaling.

So, in short, I would argue that junk food is addictive, yes.

Maybe everyone should just toughen up and find some will power? Or perhaps some are just more prone to addiction and a glp levels the playing field? Maybe the way you feel, normally, is how someone feels with a glp turning things down a bit...

Of course junk food is addictive, after all, in things like Big Macs, for example, there are a lot of flavor aromas, which are only supposed to stimulate dopamine more. I think someone even mentioned here in PM that corporations like McDonald's are VERY unhappy with glp1 because it's ruining their business.

 

[qbkilla]

Do you come off your antidepressant drugs if you start feeling better when taking them

So like antidepressant drugs, glp users become reliant on a drug in order to change behavior. If they were to lose access to their drug, they would revert to their old ways?

They can't have it both ways where they claim behavior change, but also claim they are not now dependent on the drug.

 

[iwantmass]

So like antidepressant drugs, glp users become reliant on a drug in order to change behavior. If they were to lose access to their drug, they would revert to their old ways?

They can't have it both ways where they claim behavior change, but also claim they are not now dependent on the drug.

Seeing as you claim to know no one that takes these, how do you know so many people that claim they change their lifestyle habits? Is a lifestyle habit necessary for a 400 lb person witn no will power to see notable improvement in health/quality of life? Is that the yard stick that we measure who gets drugs? Or are we just thankful that the 400 lb person is now 200 lbs and notably more healthy, even though they dont practice a more fit lifestyle? Ive told ppl all along that these will most likely be lifestyle drugs for the general population. And thats okay

 

[specter]

There's a pretty strong argument for junk food actually being addictive. It's hyper palatable and engineered to keep one coming back for more.

I can bake some pretty delicious, decadent cookies and be good after a few. Yet, I could absolutely crush a box of Oreos without issue... That's by design.

Foods packed full of salt, sugar and fat cause a rapid rise of dopamine in the brain's reward center, much the same as nicotine or cocaine... Not of the same magnitude of cocaine but it can be on par with nicotine.

Then there's the availability. If you need a "quick fix" there's probably something in your cupboard or at the corner store a block away. In polls, some people have reported quitting junk food to be more difficult than cigarettes or alcohol.

I, coincidentally, have been doing some reading about the food industry lately lol but I do believe processed foods are addictive. And, like other substances, that addiction varies from one person to another.

Some use glp1s and continue to eat junk, sure. But for some, a glp will help break that habit, and others as well. There are human studies underway looking at semaglutide and liraglutide as treatment options for alcohol use disorder. Also animal studies for nicotine, cocaine, amphetamines, heroin... And I've seen plenty of people say they started a glp to lose weight and ended up quitting smoking or something similar.

They seem to reduce dopaminergic signaling. And I definitely feel that, myself. Even a very low dose takes away cravings and kinda removes the reward if I do indulge. I get on great with tirzepatide but retatrutide gives me restless legs pretty bad... Another indicator of reduced dopaminergic signaling.

So, in short, I would argue that junk food is addictive, yes.

Maybe everyone should just toughen up and find some will power? Or perhaps some are just more prone to addiction and a glp levels the playing field? Maybe the way you feel, normally, is how someone feels with a glp turning things down a bit...

McDonalds made the hamburger so it almost shouldnt require chewing to eat.. its all made to be addictive.. very..

 

[KingOfSushi]

So like antidepressant drugs, glp users become reliant on a drug in order to change behavior. If they were to lose access to their drug, they would revert to their old ways?

Possibly yes. That’s how most drugs work.

 

[alfresco]

Beat me to it. These compounds are really being created to offset the muscle loss from GLP’s.

Two reported deaths during the trials with trevogrumab, five I believe with Garetosmab along with nose bleeds and connective tissue issues. They were also created to be used in combination to offset discontinued use of each other due to effects.

Are these going to replace gear? Absolutely not IMO. These are to preserve muscle loss during a cut and will likely be another set of tools like GLP’s for competitors to use during prep.

Will some bodybuilders try and abuse them to find a new hack or where the line is? Absolutely they will. That’s bodybuilders. lol

When the grass looks greener the water bill is higher.

 

[Muay Thai]

hmu i got rx on alll relax goods pharma quality hmu

 

[need4tren]

I’m so tired of this guy and his obsession to get views on non sense