Just went to a seminar hosted by some younger (50ish) TRT docs who seem to be well schooled on the latest studies and practices. I posed some of these questions to them and they agree that YES, 70 mg per week is in the range of a normal middle age man. But, that is not Optimal. They strive for optimal T levels. They believe that a guy with a total T (they focused more on free T, but used total T as an example) who has a number of 300-400 is within range but a guy at 800-900 would enjoy a better quality of life when it comes to sex drive, sleep, muscle mass, body fat etc. And they believe that higher end of the spectrum will lead to a longer life as long as ancillary conditions are kept in check. Blood pressure being most important but they also cited hematocrit, hemoglobin, and cholesterol. That said, they were AGAINST using an estrogen block in most cases. They believe the average weekly sweet spot is individual dependent, but most guys will get to that 800-900 range at 150-200 per week divided into smaller doses.