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Nick Trigili’s Hydronics H2O (hyaluronic Acid)?!?!

HA products are typical fpr facial injections, like getting lips or cheekbones plumped up. Not sure if its anything similar... but the body will chew through that like a supplement, especially if low-carb dieting
 
I don't see any mention of cross-linking in this product, which is important if it's to remain at the injection site. It's just called "Pure sterilized Hyaluronic Acid powder."

1. Tezel A, and Fredrickson GH. The science of hyaluronic acid dermal fillers. Journal of cosmetic and laser therapy: official publication of the European Society for Laser Dermatology 10: 35-42, 2008.

"Such a solution is known as free HA, uncrosslinked
HA, or non-modified HA. If this solution
was to be used as a dermal filler, the product would
be rapidly eliminated from the injection site (in less
than a week). This results from the very limited
residence time of uncrosslinked HA polymers in the
skin as the body quickly breaks down HA chains that
are not crosslinked into a gel (see below). Enzymes
such as hyaluronidase and free radicals that are
naturally present in the skin can quickly degrade
uncrosslinked HA polymers, cleaving off large
portions of the polymer chains at a time. As a result,
its half-life is 1–2 days in tissue, where it undergoes
aqueous dilution and then, in the liver, enzymatic
degradation to water and carbon dioxide (5).
Therefore, uncrosslinked HA solutions do not
provide the persistence required of a dermal filler
(6)."

-S
 
A few months ago everyone here was praising Nick for speaking the truth on his YouTube channel, lol.
You can be selectively honest [emoji846]

Everyone's trying to make a buck...I won't hesitate spending it towards the people who provide value (JM, Jordan Peters, Scott Stevenson...etc), just like a car enthusiast wouldn't hesitate spending money on a quality mechanic.

It's just this whole thing is riddled with this stuff now; every video talking about the secret of the pros...yada yada yada...kids training for 3 years injecting site enhancement oils lol...

People are building the car backwards nowadays

Sent from my Pixel XL using Tapatalk
 
You can be selectively honest [emoji846]

Everyone's trying to make a buck...I won't hesitate spending it towards the people who provide value (JM, Jordan Peters, Scott Stevenson...etc), just like a car enthusiast wouldn't hesitate spending money on a quality mechanic.

It's just this whole thing is riddled with this stuff now; every video talking about the secret of the pros...yada yada yada...kids training for 3 years injecting site enhancement oils lol...

People are building the car backwards nowadays

Sent from my Pixel XL using Tapatalk

One of those guys has actually promoted a pre mixed HA product recently. When I saw that I looked into it again as I thought there may be something to it. The science isn't there but I have been reading many positive reviews on IG so I was gonna give it ago. But a few people who I trust have told me it's not worth it. Nick Trigilli was originally promoting this stuff lasting months so that caught my eye but everything I hear is a fews days max if it even works at all. I see people on this thread generally have the same opinion. Getting a great pump is fantastic but I have training, cialis, l-citrulline etc for that. Although synthelator is great and only works short term so I don't mind using something for short term results. I don't need to pay $30 for a pump though. I know syntherol works for site enhancement amazingly well and if you are consistent it should product excellent results. I had hoped this could be useful as well but I don't see it. If I had a bottle on me I would try it out but not gonna pay out with all the shipping (plus custom issues etc) for something I don't believe in.
 
I don't see any mention of cross-linking in this product, which is important if it's to remain at the injection site. It's just called "Pure sterilized Hyaluronic Acid powder."

1. Tezel A, and Fredrickson GH. The science of hyaluronic acid dermal fillers. Journal of cosmetic and laser therapy: official publication of the European Society for Laser Dermatology 10: 35-42, 2008.

"Such a solution is known as free HA, uncrosslinked
HA, or non-modified HA. If this solution
was to be used as a dermal filler, the product would
be rapidly eliminated from the injection site (in less
than a week). This results from the very limited
residence time of uncrosslinked HA polymers in the
skin as the body quickly breaks down HA chains that
are not crosslinked into a gel (see below). Enzymes
such as hyaluronidase and free radicals that are
naturally present in the skin can quickly degrade
uncrosslinked HA polymers, cleaving off large
portions of the polymer chains at a time. As a result,
its half-life is 1–2 days in tissue, where it undergoes
aqueous dilution and then, in the liver, enzymatic
degradation to water and carbon dioxide (5).
Therefore, uncrosslinked HA solutions do not
provide the persistence required of a dermal filler
(6)."

-S

100% this as I mentioned. Crosslinked....
What's being sold is a plant based HA powder.
If it's dosed right (near juvederm dosages) mixed HA takes awhile to look safe for injection. I'm talking hours to look "dissolved"
The amount of HA must be pretty low if it dissolves quick into solution. Is this product ready to inject after mixing? Regardless though...its not crosslinked. It's not gonna last in the body long enough to "attach" to muscle fibers. Watch...after all this cross linking talk. Suddenly he's gonna say it is crosslinked, or come out with an ADVANCED formula.
 
You can be selectively honest [emoji846]

Everyone's trying to make a buck...I won't hesitate spending it towards the people who provide value (JM, Jordan Peters, Scott Stevenson...etc), just like a car enthusiast wouldn't hesitate spending money on a quality mechanic.

It's just this whole thing is riddled with this stuff now; every video talking about the secret of the pros...yada yada yada...kids training for 3 years injecting site enhancement oils lol...

People are building the car backwards nowadays

Sent from my Pixel XL using Tapatalk

My opinion on Nick has changed nuermous times. I am not quite sure how to take him. Sometimes he comes across as a no bullshit guy who obviously has lot's of experience but is not the sharpest knife. Other times I think he is literally trying to make as much income as possible and doesn't mind stretching the truth to make it. I have him on IG and he seems honest but then I read other stuff or hear things on the forums and I am back to thinking the opposite. Although I will say if there is a product that is relatively easy to manufacture I am always wary of guys who act like all of their competitors have crap product and their product is the only good one.
 
My opinion on Nick has changed nuermous times. I am not quite sure how to take him. Sometimes he comes across as a no bullshit guy who obviously has lot's of experience but is not the sharpest knife. Other times I think he is literally trying to make as much income as possible and doesn't mind stretching the truth to make it. I have him on IG and he seems honest but then I read other stuff or hear things on the forums and I am back to thinking the opposite. Although I will say if there is a product that is relatively easy to manufacture I am always wary of guys who act like all of their competitors have crap product and their product is the only good one.




he's Italian..



that's all you really need to know :eek: (no bully pls spaghetti bros)
 
My interest is atrophied quads that I have from multiple surgeries. I thought possibly the sustained pump could help stretch the fascia and help with growth. Maybe that isn’t the case...
 
I did some research on this stuff many years ago when I was looking into polysulfated glycosaminoglycans (adequan), HA is a glycosaminoglycan. It is commonly used in horses with good results (just like adequan).

For me, the fact that it was a cancer promoter (it actually protects cancerous cells) was a major turn off.

From what I just read on it, it seems that everyone is correct, it would take the crosslinked HA gel to have a chance to be effective.

I have to wonder, do many of these substances promote site inflammation and thus whole body inflammation? Because if they do, it would probably promote heart disease...
 
I have to wonder, do many of these substances promote site inflammation and thus whole body inflammation? Because if they do, it would probably promote heart disease...

Someone posted a thread recently about injections (general) and overall inflammation levels. Excluding bad shots (unsterile products) I generally don't think it would be a concern. Perhaps it could be with HA products... I don't know. Blood markers are only an indication but CRP is a great one to gauge overall inflammation levels (from local or systemic events). It's also be shown an accurate predictor of cardiovascular mortality in recent studies. I have had my CRP tested on syntherol cycles and it's been low. My choice of supplements I am sure has helped that but there was no increase in levels from daily injection of syntherol in the same muscles.
 
I did some research on this stuff many years ago when I was looking into polysulfated glycosaminoglycans (adequan), HA is a glycosaminoglycan. It is commonly used in horses with good results (just like adequan).

For me, the fact that it was a cancer promoter (it actually protects cancerous cells) was a major turn off.

From what I just read on it, it seems that everyone is correct, it would take the crosslinked HA gel to have a chance to be effective.

I have to wonder, do many of these substances promote site inflammation and thus whole body inflammation? Because if they do, it would probably promote heart disease...

he markets it as, "Extremely safe" and having, "zero side effects" on instagram. As if that could be said of any foreign substance being injected into the body.

Irresponsible idiot peddling shit he doesn't understand for a buck. Hope the business goes under.
 
I did some research on this stuff many years ago when I was looking into polysulfated glycosaminoglycans (adequan), HA is a glycosaminoglycan. It is commonly used in horses with good results (just like adequan).

For me, the fact that it was a cancer promoter (it actually protects cancerous cells) was a major turn off.

From what I just read on it, it seems that everyone is correct, it would take the crosslinked HA gel to have a chance to be effective.

I have to wonder, do many of these substances promote site inflammation and thus whole body inflammation? Because if they do, it would probably promote heart disease...

He describes it as being like a gel once you reconstitute it.
 
Ive used it and love the stuff, havent lost the size i gained from using it and yes once you mix the bac water with it, it does become a gel.

Ive used it once a week in arms and shoulders and the results have been really good....got several people using it at my gym and they all say the same, not sure why other people are reporting it as useless?

Definately didnt disappear overnight..i ran it for 6 weeks and its been 3 weeks since my last shot and everything still looks pumped and full
 
Ive used it and love the stuff, havent lost the size i gained from using it and yes once you mix the bac water with it, it does become a gel.

Ive used it once a week in arms and shoulders and the results have been really good....got several people using it at my gym and they all say the same, not sure why other people are reporting it as useless?

Definately didnt disappear overnight..i ran it for 6 weeks and its been 3 weeks since my last shot and everything still looks pumped and full
1 post and it's this review? But your registration date is old. You sign up then creep only to post once, happening to hype this product?

Credibility rating: 6% - Thanks for your contribution.
 
Last edited:
Ive used it and love the stuff, havent lost the size i gained from using it and yes once you mix the bac water with it, it does become a gel.

Ive used it once a week in arms and shoulders and the results have been really good....got several people using it at my gym and they all say the same, not sure why other people are reporting it as useless?

Definately didnt disappear overnight..i ran it for 6 weeks and its been 3 weeks since my last shot and everything still looks pumped and full

using the same terminology as trigili the rip off king
 
100% this as I mentioned. Crosslinked....
What's being sold is a plant based HA powder.
If it's dosed right (near juvederm dosages) mixed HA takes awhile to look safe for injection. I'm talking hours to look "dissolved"
The amount of HA must be pretty low if it dissolves quick into solution. Is this product ready to inject after mixing? Regardless though...its not crosslinked. It's not gonna last in the body long enough to "attach" to muscle fibers. Watch...after all this cross linking talk. Suddenly he's gonna say it is crosslinked, or come out with an ADVANCED formula.

I can't post it here the name...

But lol Nick is an idiot. It's just HA powder in water. The more Ha the thicker the solution.


Yes, this is what I was thinking... When they talk about it being a "gel," it seems that it could be as simple as just making a more concentrated solution (using less water)...

Do you think this could work?
 

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