Nick Trigili’s Hydronics H2O (hyaluronic Acid)?!?!

[11111]

I don't see any mention of cross-linking in this product, which is important if it's to remain at the injection site. It's just called "Pure sterilized Hyaluronic Acid powder."

1. Tezel A, and Fredrickson GH. The science of hyaluronic acid dermal fillers. Journal of cosmetic and laser therapy: official publication of the European Society for Laser Dermatology 10: 35-42, 2008.

"Such a solution is known as free HA, uncrosslinked
HA, or non-modified HA. If this solution
was to be used as a dermal filler, the product would
be rapidly eliminated from the injection site (in less
than a week). This results from the very limited
residence time of uncrosslinked HA polymers in the
skin as the body quickly breaks down HA chains that
are not crosslinked into a gel (see below). Enzymes
such as hyaluronidase and free radicals that are
naturally present in the skin can quickly degrade
uncrosslinked HA polymers, cleaving off large
portions of the polymer chains at a time. As a result,
its half-life is 1–2 days in tissue, where it undergoes
aqueous dilution and then, in the liver, enzymatic
degradation to water and carbon dioxide (5).
Therefore, uncrosslinked HA solutions do not
provide the persistence required of a dermal filler
(6)."

-S

100% this as I mentioned. Crosslinked....
What's being sold is a plant based HA powder.
If it's dosed right (near juvederm dosages) mixed HA takes awhile to look safe for injection. I'm talking hours to look "dissolved"
The amount of HA must be pretty low if it dissolves quick into solution. Is this product ready to inject after mixing? Regardless though...its not crosslinked. It's not gonna last in the body long enough to "attach" to muscle fibers. Watch...after all this cross linking talk. Suddenly he's gonna say it is crosslinked, or come out with an ADVANCED formula.

Forgive my ignorance on this topic, but would it be possible to purchase "crosslinked" hyaluronic acid powder?

Or is the "cross-linking" process something that would have to be done to the already formulated powder?

 

[GreenEarth]

Ive used it and love the stuff, havent lost the size i gained from using it and yes once you mix the bac water with it, it does become a gel.

Ive used it once a week in arms and shoulders and the results have been really good....got several people using it at my gym and they all say the same, not sure why other people are reporting it as useless?

Definately didnt disappear overnight..i ran it for 6 weeks and its been 3 weeks since my last shot and everything still looks pumped and full

Seems legit

 

[Beti ona]

Seems legit

I just ordered a lot!

 

[Kaladryn]

He describes it as being like a gel once you reconstitute it.

Ive used it and love the stuff, havent lost the size i gained from using it and yes once you mix the bac water with it, it does become a gel.

Ive used it once a week in arms and shoulders and the results have been really good....got several people using it at my gym and they all say the same, not sure why other people are reporting it as useless?

Definately didnt disappear overnight..i ran it for 6 weeks and its been 3 weeks since my last shot and everything still looks pumped and full

Yes, this is what I was thinking... When they talk about it being a "gel," it seems that it could be as simple as just making a more concentrated solution (using less water)...

Do you think this could work?

Forgive my ignorance on this topic, but would it be possible to purchase "crosslinked" hyaluronic acid powder?

Or is the "cross-linking" process something that would have to be done to the already formulated powder?

A "cross-linked gel HA" is much more complex than just producing a substance with a gel consistency, that is why this product is snake oil, he is trying to pawn it off as something much more complex (and expensive)...

Crosslinking method of hyaluronic-based hydrogel for biomedical applications

The fabrication of HA materials has been achieved using a variety of chemical modifications to provide mechanically and chemically robust materials. These HA derivatives have physicochemical properties that may be significantly different from the native polymer, but most derivatives maintain the biocompatibility and biodegradability of native HA. The most common modification of HA is crosslinking to form a hydrogel. However, the resilience of HA hydrogels relies on their ability to resist degradation by hyaluronidases and reactive oxygen and nitrogen species, thus limiting their efficient usage. To overcome problems with HA degradation, functional groups on HA have been exploited in the preparation of HA-based materials. The chemical structure of HA highlighting the three most commonly used sites of covalent modification, the carboxylic groups, hydroxyl group, and –NHCOCH3 group is shown in Figure 1.

 

[Cinder]

Forgive my ignorance on this topic, but would it be possible to purchase "crosslinked" hyaluronic acid powder?

Or is the "cross-linking" process something that would have to be done to the already formulated powder?

There's a cross linked gel on eBay lol.
But don't think u should inject that.

 

[Thebigone]

I ordered some because I have a decent amount of disposable income and figured it might help during a bulk but I’m not setting my sights too high.

 

[thethinker48]

[ame="https://www.youtube.com/watch?v=zI6Zz_MiMb4"]https://www.youtube.com/watch?v=zI6Zz_MiMb4[/ame]

He posted another video on it.

"Sterile water will degrade this into nothing, use bacteriostatic water, it will also sting with sterile water"

 

[mementomori515]

Oh the best part about this is how he only posts demo videos on his forum, which costs 10$ per month to view. And his excuse is that he can't post them on youtube or instagram

 

[G.I.Bro]

Oh the best part about this is how he only posts demo videos on his forum, which costs 10$ per month to view. And his excuse is that he can't post them on youtube or instagram

To be fair, pay apps/access/forums are the new "thing." Meadows has had one forever. JPs is absolutely killing it with huge subscription numbers on his. Palumbo is now trying it with the pay app/subscription content model. Many more... Not just Nick. By no means endorsing, just saying.

 

[KillerStack]

I seem to remember him saying it will sit
in the muscle for 6 or 12 months (forget which, but a long time) so there is no need for repeat injections.
Now I see guys on his IG saying they use it regularly
on say arm days for example. Personally if I were to
try this I'd prefer something that lasts a short time, because if it wouldn't agree with you for some reason
it sound better if it degrades pretty quickly. Anyone see
any potential problems with this stuff? There's bound to be a downside, but who knows.

 

[Reno911]

The guy is not trustworthy at all. Tune in here the other day when he talks about switching tops when he was selling GH. He just has a pretty bad track record across the board in pretty much everything he's ever been involved in. I'm not against SEO but I certainly wouldn't inject anything that he's involved with.


Start about 57 minutes in.

[ame="https://www.youtube.com/watch?v=Ix9I6TrnalU"]East Coast Pros -Nick Trigili , Dom Cardone, Jeff Long - YouTube[/ame]

 

[whoremoan]

What is he's paid site like ? Any useful info ?


Sent from my iPhone using Tapatalk

 

[TheOtherOne55]

This doesnt surprise me.

And if you look around and reviews, SYNTHEROL is the only SEO that has overwhelmingly positive reviews from thousands of people.

**EDIT** - THAT PRODUCT ISN'T ALLOWED TO BE MENTIONED ON THIS SITE!

and NOWWW we have this shit Nick is pushing. And right off the bat we are seeing people like it or hate it. That's not a good thing.


Go back to the tried and true. Just reminds me of our industry in general...
"Hey man, try this legal prohormone. It's just as good as a cycle."
"Hey man, try this SARM. It's just as good as a cycle."
Uh no, just go run some test...

 

[Elvia1023]

This doesnt surprise me.

And if you look around and reviews, SYNTHEROL is the only SEO that has overwhelmingly positive reviews from thousands of people.

**EDIT** - THAT PRODUCT ISN'T ALLOWED TO BE MENTIONED ON THIS SITE!

and NOWWW we have this shit Nick is pushing. And right off the bat we are seeing people like it or hate it. That's not a good thing.


Go back to the tried and true. Just reminds me of our industry in general...
"Hey man, try this legal prohormone. It's just as good as a cycle."
"Hey man, try this SARM. It's just as good as a cycle."
Uh no, just go run some test...

Completely agree. It's one thing then the next. Although I will say SARM's can be good but when I watch EA I have to :banghead: They still say they have no side effects and just results and they are just as good as steroids 40mg+ LGD-4033 no side effects and no impact on health :banghead: I thought LGD was quite good at 10mg. RAD-140 gave me more side effects than adrol and I had to stop it

I will say I have seen so many guys say how this product is amazing but no pics. It's the sort of product that demands pics. Granted guys can still bullshit with pics but if you put 2 inches on your arms in 1 week show the results.

 

[muskate]

I have a buddy that tried this stuff and he was blown away. He said he had a constant pump for 3 days! I have seen hyaluronic acid before but never read about it in an injectsble form. Just wanted to see if anybody had tried this stuff and what y’all thought.

He has a few videos on YouTube explaining the product; could be promising.

I don't know much about it but I just had PJ on my podcast and he backed up Nick 100%.

Seems like a lot of top pros are using.

 

[Massive G]

Imagine what you could do with $300 worth of food.

Save pinholes and use (as mentioned above) cit mal, glycerine, sea salt baking soda cialis etc...

Everyone's out to make a quick buck and with social media and other promotional sources that don't cost money ...it's an advertising free snake oil salesman's dream...

 

[Explorerspl]

I don't know much about it but I just had PJ on my podcast and he backed up Nick 100%.

Seems like a lot of top pros are using.

Nick admitted to paying some of these guys for interviews,he's not above paying them to say "great product bro"?

Plus him and PJ are in bed together now

 

[suppdude]

I don't know much about it but I just had PJ on my podcast and he backed up Nick 100%.

Seems like a lot of top pros are using.

Thats because Nick signed with Blackstone so of course PJ is going to back what Nick says.

 

[MaconiDDS]

I haven't read all the posts but I did see Jerry Ward discuss this and unfortunately I doubt most of the viewers realize the active ingredient is associated with cancer.

 

[Thebigone]

How is he even allowed to legally sell this? On the bottles it says for topical use only and that would’ve worked fine but all his videos demonstrating how to inject it would completely negate the legal aspect of getting around it.