plague build-up

[Knight9]

Scary thing is that it doesn't take a whole bunch of plaque building up and blocking your coronaries to kill you. You can have what happened to me. They think a small plaque broke off in my right main coronary artery and then my blood freaked out and made a huge clot. The clot blocked blood flow, not atherosclerosis and plaque. Once they cleared out my clot it was 100% open. Surgeon was wanting to put a stent in but they didn't have one large enough for my artery. So I didn't really need one.

I think the high blood pressure you get when lifting really heavy is what did it for me. The pressure blows that plaque right off and it is seen as damage to the vessel. Blood starts a clot. I was squatting real heavy for me. Doing 455 for sets of 8 to 10.

I also came across something recently where a doctor was saying Vitamin K softens plaque and that might be exactly what you don't want to do...because you'd rather have hard plaque than soft plaque that is usually the kind that easily breaks free. I need to look for this and post it up...I'm not really sure if this is how it works or just some random doctor trying to have a different opinion.

 

[rmtt]

I also came across something recently where a doctor was saying Vitamin K softens plaque and that might be exactly what you don't want to do...because you'd rather have hard plaque than soft plaque that is usually the kind that easily breaks free. I need to look for this and post it up...I'm not really sure if this is how it works or just some random doctor trying to have a different opinion.

That's a scary thought.....hadn't thought of it in that aspect.

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[nothuman]

Agreed. PQQ seems pretty awesome thus far. I guess what I meant by that post is that atherosclerosis was semi reversed thru a drug who's main mechanisim is PTB1B inhibition... and PQQ is a PTB1B inhibitor... therefor it might be effective in reversing atherosclerosis too? Maybe I'm assuming too much.. but just throwing it out there!

Ah good thinking. I've never had a CT scan to check my calcium score before but my bloodwork and echo cardiograms seems to suggest I don't have much plaque. Of course I can't know for sure so I do everything in my power for prevention/reversal of plaque. Lp(a) is a nice little blood test that could provide a clue.

 

[warlock]

Ah good thinking. I've never had a CT scan to check my calcium score before but my bloodwork and echo cardiograms seems to suggest I don't have much plaque. Of course I can't know for sure so I do everything in my power for prevention/reversal of plaque. Lp(a) is a nice little blood test that could provide a clue.

Do you think the only or best blood work test we can get done to test if we have plaque is Lp(a)?

 

[pickapeck]

Don't do anything fun in life like chase women, drink whiskey or snort coke off the crack of a strippers hairy mound. Never ever ever watch porn. Eat chicken rice and spinach and occasionally liver and onions. Sleep 8 hours a night. Do yoga in your basement. Live board to death for 120 years.

 

[pickapeck]

Do you think the only or best blood work test we can get done to test if we have plaque is Lp(a)?

My great grandfather died at 86 of a bleeding ulcer. At the time he had a 48 year old girlfriend. My father walked in on them. He smoked cigars and drank whisky every day. He never went to a doctor.

 

[nothuman]

Do you think the only or best blood work test we can get done to test if we have plaque is Lp(a)?

I don't know the answer to this question for sure, but I believe LDL particle number, Apo-B, and Lp(a) are some of the best. Here is a link I found.

https://www.docsopinion.com/health-and-nutrition/lipids/lipoprotein-a/

 

[maldorf]

I also came across something recently where a doctor was saying Vitamin K softens plaque and that might be exactly what you don't want to do...because you'd rather have hard plaque than soft plaque that is usually the kind that easily breaks free. I need to look for this and post it up...I'm not really sure if this is how it works or just some random doctor trying to have a different opinion.

I think I have heard that actually and it make logical sense. Not sure though. I think it becomes like one of those mints with juice in the center and can rupture.

 

[Knight9]

I also came across something recently where a doctor was saying Vitamin K softens plaque and that might be exactly what you don't want to do...because you'd rather have hard plaque than soft plaque that is usually the kind that easily breaks free. I need to look for this and post it up...I'm not really sure if this is how it works or just some random doctor trying to have a different opinion.

Here it is..

[ame="https://www.youtube.com/watch?v=ulemSPBA3DA&t=6s"]Vit K2: What Is It? Does it Remove CV artery plaque? Does that matter? Research/viewer experience - YouTube[/ame]

and
[ame="https://www.youtube.com/watch?v=oxIF3bUgnuo&t=225s"]MESA and VIT K2: do you REALLY want to REMOVE CALCIUM from your plaque?- FORD BREWER MD MPH - YouTube[/ame]

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[Knight9]

[ame="https://www.youtube.com/watch?v=4lMv9SCb42c"]The Vulnerable Plaque Theory: Can We Predict When a Plaque Will Blow? - YouTube[/ame]

 

[Massive G]

Bromelain Bromelain Bromelain

I love this supplement :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529416/

Don't use if you are on any blood thinners or anti-biotics ...check drug supplement reactions as well.

I don't know my calcium score, either way it seems prudent (based on the videos) for me to drop supplemental vitamin k and just rely on what I ingest from my diet -veggies etc.

 

[OutToLunch]

Confusing and conflicting Medicine lol

 

[Krus8r]

Vitamin K2 helps arterial hardening

Vitamin K2 has been shown to improve arterial stiffness. There are a couple variants, both short and long acting (MK-4 and MK-7). K2 is important in activating the osteocalcin process that moves serum calcium into bones as opposed to having it settle in soft tissues (like arteries). Our food supply has devolved over the decades to the point where there is very little K2 in our diets unless we specifically seek out grass-fed sources. We also have a human trial that proves some of the value of K2 with respect to arterial hardness:

Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women

Summary
Observational data suggest a link between menaquinone (MK, vitamin K2) intake and cardiovascular (CV) health. However, MK intervention trials with vascular endpoints are lacking. We investigated long-term effects of MK-7 (180 μg MenaQ7/day) supplementation on arterial stiffness in a double-blind, placebo-controlled trial. Healthy postmenopausal women (n=244) received either placebo (n=124) or MK-7 (n=120) for three years. Indices of local carotid stiffness (intimamedia thickness IMT, Diameter end-diastole and Distension) were measured by echotracking. Regional aortic stiffness (carotid-femoral and carotid-radial Pulse Wave Velocity, cfPWV and crPWV, respectively) was measured using mechanotransducers. Circulating desphospho-uncarboxylated matrix Gla-protein (dp-ucMGP) as well as acute phase markers Interleukin-6 (IL-6), high-sensitive C-reactive protein (hsCRP), tumour necrosis factor-α (TNF-α) and markers for endothelial dysfunction Vascular Cell Adhesion Molecule (VCAM), E-selectin, and Advanced Glycation Endproducts (AGEs) were measured. At baseline dp-ucMGP was associated with IMT, Diameter, cfPWV and with the mean z-scores of acute phase markers (APMscore) and of markers for endothelial dysfunction (EDFscore). After three year MK-7 supplementation cfPWV and the Stiffness Index β significantly decreased in the total group, whereas distension, compliance, distensibility, Young’s Modulus, and the local carotid PWV (cPWV) improved in women having a baseline Stiffness Index β above the median of 10.8. MK-7 decreased dp-ucMGP by 50 % compared to placebo, but did not influence the markers for acute phase and endothelial dysfunction. In conclusion, long-term use of MK-7 supplements improves arterial stiffness in healthy postmenopausal women, especially in women having a high arterial stiffness.

 

[KEYTECH]

Bromelain

I have always recommended it to my athletes for over ten years!


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529416/



Effects of Bromelain on Cardiovascular and Circulation
Bromelain prevents or minimizes the severity of angina pectoris and transient ischemic attack (TIA). It is useful in the prevention and treatment of thrombophlebitis. It may also break down cholesterol plaques and exerts a potent fibrinolytic activity. A combination of bromelain and other nutrients protect against ischemia/reperfusion injury in skeletal muscle [23]. Cardiovascular diseases (CVDs) include disorders of the blood vessels and heart, coronary heart disease (heart attacks), cerebrovascular disease (stroke), raised blood pressure (hypertension), peripheral artery disease, rheumatic heart disease, heart failure, and congenital heart disease [24]. Stroke and heart disease are the main cause of death, about 65% of people with diabetes die from stroke or heart disease. Bromelain has been effective in the treatment of CVDs as it is an inhibitor of blood platelet aggregation, thus minimizing the risk of arterial thrombosis and embolism [25]. King et al. [26] reported that administration of medication use to control the symptoms of diabetes, hypertension, and hypercholesteromia increased by 121% from 1988–1994 to 2001–2006 (P < 0.05) and was greater for patients with fewer healthy lifestyle habits. Bromelain supplement could reduce any of risk factors that contribute to the development of cardiovascular disease. In a recent research, Bromelain was found to attenuate development of allergic airway disease (AAD), while altering CD4+ to CD8+T lymphocyte populations. From this reduction in AAD outcomes it was suggested that bromelain may have similar effects in the treatment of human asthma and hypersensitivity disorders [27]. In another study, carried out by Juhasz et al., Bromelain was proved to exhibit the ability of inducing cardioprotection against ischemia-reperfusion injury through Akt/Foxo pathway in rat myocardium [28].

 

[maldorf]

Here it is..

Vit K2: What Is It? Does it Remove CV artery plaque? Does that matter? Research/viewer experience - YouTube

and
MESA and VIT K2: do you REALLY want to REMOVE CALCIUM from your plaque?- FORD BREWER MD MPH - YouTube

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A bit of a surprise then. Taking K supplements may actually make your plaques more dangerous. I haven't heard that but it makes sense since it take away calcium and make the plaque softer, more likely to rupture then.

He also mentions how statins are shown by research to harden the plaque by causing just the opposite, calcification. Calcified they are more stable.

"Saremi and colleagues speculated that "statins may lower the lipid-rich core of atherosclerotic plaques, and may enhance the density of calcification as part of the healing process, potentially contributing to plaque stabilization and decreased cardiovascular disease events."

 

[nothuman]

A bit of a surprise then. Taking K supplements may actually make your plaques more dangerous. I haven't heard that but it makes sense since it take away calcium and make the plaque softer, more likely to rupture then.

He also mentions how statins are shown by research to harden the plaque by causing just the opposite, calcification. Calcified they are more stable.

"Saremi and colleagues speculated that "statins may lower the lipid-rich core of atherosclerotic plaques, and may enhance the density of calcification as part of the healing process, potentially contributing to plaque stabilization and decreased cardiovascular disease events."

I'd want to spend a lot of time researching this before I take it at face value. Seems to contradict everything I thought.

 

[maldorf]

Medical paper on Plaques

Talks about how they rupture. The fibrous cap breaks and then the juicy center leaks out and stimulates a clot to form. What they think happened to me. These plaques don't even have to be very big, as in my case.

Mechanisms of Plaque Formation and Rupture | Circulation Research

 

[Elvia1023]

My doctor just told me to get off vitamin k2 a few days ago. Told me to get off baby aspirin as well. Krill and fish oil she thought were good. This was in reply to me listing out my daily supplements.

 

[nothuman]

My doctor just told me to get off vitamin k2 a few days ago. Told me to get off baby aspirin as well. Krill and fish oil she thought were good. This was in reply to me listing out my daily supplements.

IMO, most doctors are some of the least credible resources when it comes to supplements that don't require a prescription. The vast majority are unaware of all the studies. The exception would be progressive doctors such as the ones we routinely post videos and links of around here (The one above, Sinatra, Mercola, Axe, etc.)

 

[Elvia1023]

IMO, most doctors are some of the least credible resources when it comes to supplements that don't require a prescription. The vast majority are unaware of all the studies. The exception would be progressive doctors such as the ones we routinely post videos and links of around here (The one above, Sinatra, Mercola, Axe, etc.)

I know matey. I even said to her it was refreshing to see a doctor like her as all the others are useless. I said most don't have a clue about hormones because I told her I used steroids (she asked me). The last doctor I told had a go at me and that wouldn't usually annoy me but the guy was short and very fat and smelt of cigarettes. I knew within 10 secs of asking why he didn't have a clue and was just being a parrot. He didn't know the most basic of things that many 18 year old newbies would know after scanning the internet for 10 mins. He didn't think estrogen could be in a male body because it's a "female hormone" and he is a GP

I do want to lower my supplements though as the number has crept up and I don't think they are all needed. I am not following her advice but I may take away the aspirin as my blood is too thin. I have posted vids of the doctor above in the past and find some of the things he has stated interesting.