Let's say it is really primo and you’re running it with no test. Then the primo is going to suppress your natural testosterone and that will raise estrogen. This situation will activate you gyno gland because you have an imbalance of test to estrogen ratio with estrogen being in a surplus.
this is 100% true
that said just running 200mg of what ever if one thing you should be able to tell what it is outside of the above fact.