There's suggestive evidence that's been observed from both in-vivo and in-vitro studies that Tamoxifin impacts the efficacy of functionality of HDL by impairment of reverse cholesterol transport. In other-words, this impacts on how effectively HDL removes LDL cholesterol from the artery wall.
In the end. It's not about the quantity of HDL, it's about the quality of HDL.
There's suggestive evidence that's been observed from both in-vivo and in-vitro studies that Tamoxifin impacts the efficacy of functionality of HDL by impairment of reverse cholesterol transport. In other-words, this impacts on how effectively HDL removes LDL cholesterol from the artery wall.
In the end. It's not about the quantity of HDL, it's about the quality of HDL.