Retatrutide

[SouthernMuscle]

because i didn't want to say 'dick skin'

Fair point

 

[blazencruise]

Wonder what people did before that

Eh, no. You didn’t frame the post quoted below as an opinion. You stated it as fact



So I skimmed through your link and I can see what the dose range is that’s therapeutic with sides that are still manageable.

The question is did you?
Talking like a smartass “common knowledge blah blah “

1-4mg per kg of bodyweight per day is not what I’d call a narrow window.

let’s say I weigh 265. I can take anywhere between 120mg and 360mg per day without even touching the 4mg/kg dose

I don’t see the anybody giving a shit about the fda black box warning for all Glp1 meds about thyroid c-cell tumors.

Everyone has their bias and opinion and that’s fine, but DNP has uses

Comparing the dubious relationship of medullary thyroid cancer and glps and the well established toxic effects of DNP is either willful ignorance or deliberately done in bad faith lol.

"I wonder what people did before that"
Never said its impossible to lose weight without them. I'm making the argument that GLP-1s make a literal explosive precursor obsolete. You do not need it. If you can't get to sub 15% bodyfat with GLPs only, that is a skill issue on your part.

 

[gauge22-v2]

Started DNP a few days back.

Today during leg day I was pouring with sweat....like when I go hiking in 30C weather. It was ridiculous.

Prior, using DNP (same dose same supplier) I have never sweated this much.

Could this be interaction with Reta?

 

[Fleezy]

Comparing the dubious relationship of medullary thyroid cancer and glps and the well established toxic effects of DNP is either willful ignorance or deliberately done in bad faith lol.

"I wonder what people did before that"
Never said its impossible to lose weight without them. I'm making the argument that GLP-1s make a literal explosive precursor obsolete. You do not need it. If you can't get to sub 15% bodyfat with GLPs only, that is a skill issue on your part.

everything you said is correct bro


referring to DNP as an 'explosive precursor' is pointless hyperbole


that aside, no one here - certainly not I, am talking about sub 15% bodyfat


im talking onion skin

 

[Fleezy]

Started DNP a few days back.

Today during leg day I was pouring with sweat....like when I go hiking in 30C weather. It was ridiculous.

Prior, using DNP (same dose same supplier) I have never sweated this much.

Could this be interaction with Reta?

reta increases metabolic rate, so i imagine it would increase sweating - especially when combined with DNP, yes

 

[SouthernMuscle]

Comparing the dubious relationship of medullary thyroid cancer and glps and the well established toxic effects of DNP is either willful ignorance or deliberately done in bad faith lol.

I’m saying there’s bad points for most drugs. And most people choose to ignore what they don’t want to believe.

The FDA put their highest warning on those drugs. Must be based on SOMETHING
I don’t know what it’s based on nor do i care. However i certainly don’t go around mentioning the warning whenever glp’s are brought up. And i don’t care who uses them. People will do as they wish, not my job to police the choices of adults.

I will push back on fear mongering though

Just because you’re scared of DNP, have never used it and don’t understand it is no reason to shit on it.

"I wonder what people did before that"
Never said its impossible to lose weight without them. I'm making the argument that GLP-1s make a literal explosive precursor obsolete. You do not need it. If you can't get to sub 15% bodyfat with GLPs only, that is a skill issue on your part.

Lol DNP will NEVER be obsolete. The fact that you even say that shows you know zero about it.

I choose not to use GLP’s. I choose to use DNP. Not because i need it, but because i like it and respond well to it.

ive used both glp’s and dnp. That’s how i formed my opinion. Can you say the same

 

[Fleezy]

as im sure i previously mentioned


the FDA approved thalidomide for pregnant women for morning sickness



so anyone who cites the FDA as a reliable source.... i imagine your IQ to be in the low 60's

 

[SouthernMuscle]

as im sure i previously mentioned


the FDA approved thalidomide for pregnant women for morning sickness



so anyone who cites the FDA as a reliable source.... i imagine your IQ to be in the low 60's

Alls I’m doing is pointing things out

Like this excerpt from the other kids link:

In 1938, the FDA declared DNP to be “extremely dangerous and not fit for human
consumption”

So what does it all mean


Just gonna do what I’m gonna do and point out inaccuracies where I see fit

 

[Stewie]

- Inhibition of mitochondrial pyruvate transport, rather than pyruvate itself, stimulates hair growth by forcing dormant stem cells to shift their metabolism, activating hair follicle growth.

- DNP acts as a protonophore (proton carrier) that dissipates the proton gradient across membranes, which is essential for certain pyruvate transport systems. It has been shown to have a significant inhibitory effect on pyruvate transport rates



ho-lee shit



@Stewie - am i interpreting this correctly? does DNP indeed improve hair growth in the way i am reading this?


if so, lmao

Interesting, I dunno?

Being as widespread that DNP has been used over the years, I would only like to believe there would have been some platforms–individuals mentioning anecdotal reports. It was pushed for weight loss back in the '30s and the miners that were the unbeknownst guinea pigs during their mining days. I don't recall any publications denoting this as a reported "effect".

 

[Fleezy]

Interesting, I dunno?

Being as widespread that DNP has been used over the years, I would only like to believe there would have been some platforms–individuals mentioning anecdotal reports. It was pushed for weight loss back in the '30s and the miners that were the unbeknownst guinea pigs during their mining days. I don't recall any publications denoting this as a reported "effect".

guess i volunteer as tribute to be the guinea pig


i'll note when i start in my log (link in my signature)

 

[Stewie]

Fascinating narrative.

GLP-1/GIP agonists and cancer: mechanisms, evidence, and nutrition implications

Obesity and diabetes increase cancer risk through insulin resistance, chronic inflammation, and altered growth signaling. Glucagon-like peptide-1 (GLP-1) receptor agonists and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) agonists

www.academia.edu

 

[blazencruise]

I’m saying there’s bad points for most drugs. And most people choose to ignore what they don’t want to believe.

The FDA put their highest warning on those drugs. Must be based on SOMETHING
I don’t know what it’s based on nor do i care. However i certainly don’t go around mentioning the warning whenever glp’s are brought up. And i don’t care who uses them. People will do as they wish, not my job to police the choices of adults.

I will push back on fear mongering though

Just because you’re scared of DNP, have never used it and don’t understand it is no reason to shit on it.

Lol DNP will NEVER be obsolete. The fact that you even say that shows you know zero about it.

I choose not to use GLP’s. I choose to use DNP. Not because i need it, but because i like it and respond well to it.

ive used both glp’s and dnp. That’s how i formed my opinion. Can you say the same

If you want to risk it, you're an adult and have the freedom to do so, and you are entitled to your opinion. But so am I, and I'll voice it. Here's some more evidence on DNP's negative effects, as food for thought though . Within dosage range people here have taken BTW. If people wanna believe anecdotal reports over the CDC, that's on them.
https://www.atsdr.cdc.gov/ToxProfiles/tp64-c1-b.pdf

 

[SouthernMuscle]

If you want to risk it, you're an adult and have the freedom to do so, and you are entitled to your opinion. But so am I, and I'll voice it. Here's some more evidence on DNP's negative effects, as food for thought though . Within dosage range people here have taken BTW. If people wanna believe anecdotal reports over the CDC, that's on them.
https://www.atsdr.cdc.gov/ToxProfiles/tp64-c1-b.pdf

I’m not reading any more shit dude. Yeah I’ve been risking it for YEARS. You started gear less than a year ago. You’re nothing but speculation.

 

[BALDNAZI]

I’m saying there’s bad points for most drugs. And most people choose to ignore what they don’t want to believe.

The FDA put their highest warning on those drugs. Must be based on SOMETHING
I don’t know what it’s based on nor do i care. However i certainly don’t go around mentioning the warning whenever glp’s are brought up. And i don’t care who uses them. People will do as they wish, not my job to police the choices of adults.

I will push back on fear mongering though

Just because you’re scared of DNP, have never used it and don’t understand it is no reason to shit on it.

Lol DNP will NEVER be obsolete. The fact that you even say that shows you know zero about it.

I choose not to use GLP’s. I choose to use DNP. Not because i need it, but because i like it and respond well to it.

ive used both glp’s and dnp. That’s how i formed my opinion. Can you say the same

I’ve used both. Reta is all I need and I’ll throw the rest of my DNP in the trash. Not necessary anymore but that’s me. Is it obsolete? DNP has a very specific use case especially if someone has to shred right NOW but if a person plans ahead and has time, yes it’s becoming obsolete.

 

[gauge22-v2]

If you want to risk it, you're an adult and have the freedom to do so, and you are entitled to your opinion. But so am I, and I'll voice it. Here's some more evidence on DNP's negative effects, as food for thought though . Within dosage range people here have taken BTW. If people wanna believe anecdotal reports over the CDC, that's on them.
https://www.atsdr.cdc.gov/ToxProfiles/tp64-c1-b.pdf

Took a glance at the PDF.

- No sample base (denominator)
- No ability to determine frequency of "incidences"
- Dosages vary wildly

 

[romo]

If you want to risk it, you're an adult and have the freedom to do so, and you are entitled to your opinion. But so am I, and I'll voice it. Here's some more evidence on DNP's negative effects, as food for thought though . Within dosage range people here have taken BTW. If people wanna believe anecdotal reports over the CDC, that's on them.
https://www.atsdr.cdc.gov/ToxProfiles/tp64-c1-b.pdf

OMG,, thank you so much for posting this, i am never going to use dnp again.

 

[SouthernMuscle]

I’ve used both. Reta is all I need and I’ll throw the rest of my DNP in the trash. Not necessary anymore but that’s me. Is it obsolete? DNP has a very specific use case especially if someone has to shred right NOW but if a person plans ahead and has time, yes it’s becoming obsolete.

I mean at the end of the day it’s personal preference that will guide a persons choices. I just prefer DNP

I’m not the only one that feels like that, so even just based on preferences it’ll never become obsolete.

I wouldn’t have done this otherwise, but for the sake of argument and discussion I did ask the robot overlords to quantify all available data and do a head to head comparison for a adult caucasian male 265lbs 15%bf. Also stated that the fictional subject was completely healthy with no comorbidities. I know this isn’t the final word on anything, just another data point to be considered.

Anyway, it said that a once weekly dose of 12mg Reta is roughly comparable to a 200mg/day dose of DNP

Again, not gospel but still interesting

 

[musclemuscle]

I think there was a sponsor on here years ago, Dinitro or something like that... He had crystal dnp which was supposed to be more potent or pure.. I haven't looked at dnp in years so I apologize I'm not educated on the current methods of administration.
I used 200mg for a week and never again lol, it just completely destroyed my energy/workouts. Just sweating during work meetings lol good times

 

[romo]

See i ran it at 100mg a day. Try that instead. The old saying, the poison is in the dosage.

 

[BALDNAZI]

I mean at the end of the day it’s personal preference that will guide a persons choices. I just prefer DNP

I’m not the only one that feels like that, so even just based on preferences it’ll never become obsolete.

I wouldn’t have done this otherwise, but for the sake of argument and discussion I did ask the robot overlords to quantify all available data and do a head to head comparison for a adult caucasian male 265lbs 15%bf. Also stated that the fictional subject was completely healthy with no comorbidities. I know this isn’t the final word on anything, just another data point to be considered.

Anyway, it said that a once weekly dose of 12mg Reta is roughly comparable to a 200mg/day dose of DNP

Again, not gospel but still interesting

Yea, there’s no way to know that so definitely not gospel lol. Obsolete is a strong word so maybe I’ll take it down a notch. For specific use cases like I said it has its place, for the vast majority of guys it’s just not necessary. That’s as simple as I can say it. All good.