...not gonna go hypoglycemic if that's the answer you're looking for. metformin does not cause your body to produce more insulin and mk-677 does not cause a drop in blood sugar.
a lot of drug reactions are caused by commonly prescribed drugs like nonsteroidal anti-inflammatory drugs/ibuprofen, anticoagulants and diuretics. it's your body superbigd and only you have the true motivation to keep track of what you are taking. become an amateur pharmacist and do the research online and don't leave it in the hands of someone else at your pcp office.