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Sialyllactose(6-SL)

Dog-Slime

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SIALLAC muscle health - supplement name
  • 6’-Sialyllactose: 6’-SL, a clinically tested and scientifically supported novel ingredient, plays a unique function on muscle health. 6’-SL inhibits muscle protein degradation while promoting muscle protein synthesis. 6’-SL keeps muscle health by maintaining the balance between muscle protein synthesis and degradation.
  • Human Clinical Trial: 6’-SL demonstrated promising potentials for subjects with muscle health challenges in a 96-week clinical trial. (Source DOI: 10.1016/j.biopha.2023.115689)
  • Muscle Mass Increase: 6’-SL boosted an essential muscle protein (Myosin Heavy Chain) production and muscle fiber size. 6’-SL helped muscle mass increase in key lower leg muscles, Gastrocnemius and Soleus muscle. (Source DOI: 10.3390/nu16162600)
  • Muscle Strength Improvement: 6′-SL administration resulted in increased muscle strength in both normal and dexamethasone-induced muscle weakness conditions. Both cases showed a notable improvement in grip strength. (Source DOI: 10.3390/nu16162600, 10.1016/j.bbrc.2024.150892)
  • Muscle Fatigue Reduction: 6′-SL helps reduce muscle fatigue by lowering blood lactate levels, supporting better work performance during endurance exercise. (Source DOI: 10.3390/nu16172957)
  • Muscle Protein Degradation Suppression: 6′-SL suppressed muscle protein degradation pathways and recovered not only weakened muscle mass but also muscle strength in a dexamethasone-induced muscle weakness conditions in an animal clinical study. (Source DOI: 10.1016/j.bbrc.2024.150892)
That's the sellers information. Supposed to boost muscle protein synthesis, increasing strength, mass, and longevity. Couldn't find it in search? Anyone used this or got any knowledge to share?
 
No personal feedback but IN out of interest.

My knee-jerk was “another supplement scam”.

Maybe not ….?


“In conclusion, this study demonstrated that 6′-SL increased muscle mass and strength, thereby enhancing exercise performance in young C57BL/6J mice. These findings suggest that 6′-SL is both beneficial and safe for enhancing exercise performance”.
 
No personal feedback but IN out of interest.

My knee-jerk was “another supplement scam”.

Maybe not ….?


“In conclusion, this study demonstrated that 6′-SL increased muscle mass and strength, thereby enhancing exercise performance in young C57BL/6J mice. These findings suggest that 6′-SL is both beneficial and safe for enhancing exercise performance”.
MY thoughts exactly.
Why was this new to me if it works?
But there does seem to be real data confirming that it should be quite useful from what I have overlooked...
 
Surprised by the seemingly low level of interest in this but either way I have some arriving tomorrow.
My last testosterone count came in a lil high so I am off of my testo-gel until a retest but I think BPC may have restored my natural function.
Plan to take another test to see if I resume trt or not but if so it will be just enough to keep me in the ranges.
I eat well and exercise well, should be no changes to how I do things but will add in this siallac and try to add a lil extra muscle (so a small up in calories, prob just a couple protein shakes). I am on BPC 1000mcg per day taken orally, no other peptides, no added hormones.

Will try to update if things seem to go well or not.
 
It definitely sounds promising and interesting on paper.

My only reservation is that one study on subjects with “muscle health challenges”, such as muscle atrophy?

And the other study was done on mice

So it’s kind of hard to say how much of this would maybe be beneficial to bodybuilders, plus it’s newer so there’s a lot of unknowns and lack of data and anecdotal feedback


Still though.. I’d be interested to hear your experience if you do give it a run. Never heard of it until now
 
Quick ChatGPT info lists it as a kind of sugar maybe more oriented towards recovery and inflammation then maybe anabolic purposes, off a quick read?

Sialyllactose (6′-SL) = a bioactive sugar with anti-inflammatory, gut, and cognitive benefits.


For bodybuilders, it’s not a direct anabolic or performance-enhancing compound, but could be useful for gut health, recovery, inflammation control, and immune support—especially during heavy training or when taking gut-stressing supplements (like orals, NSAIDs, or high-protein diets).
 
Surprised by the seemingly low level of interest in this but either way I have some arriving tomorrow.
My last testosterone count came in a lil high so I am off of my testo-gel until a retest but I think BPC may have restored my natural function.
Plan to take another test to see if I resume trt or not but if so it will be just enough to keep me in the ranges.
I eat well and exercise well, should be no changes to how I do things but will add in this siallac and try to add a lil extra muscle (so a small up in calories, prob just a couple protein shakes). I am on BPC 1000mcg per day taken orally, no other peptides, no added hormones.

Will try to update if things seem to go well or not.
Are u confusing BPC with HCG?
 
Are u confusing BPC with HCG?
No my test was low from a brain injury which BPC is supposed to help heal. I had very high natural levels before this injury.(despite many cycles). New nurse just put me back on the gel with no retest, so I guess I will just keep it going and not worry about if I can function at mid range without, I like it being high.
 
It definitely sounds promising and interesting on paper.

My only reservation is that one study on subjects with “muscle health challenges”, such as muscle atrophy?

And the other study was done on mice

So it’s kind of hard to say how much of this would maybe be beneficial to bodybuilders, plus it’s newer so there’s a lot of unknowns and lack of data and anecdotal feedback


Still though.. I’d be interested to hear your experience if you do give it a run. Never heard of it until now
Most steroids were developed for and used on people with "muscle health challenges" to my understanding...

Advanced Muscle Support:
6’-Sialyllactose (6’-SL) is a novel, clinically tested ingredient with scientifically validated benefits for muscle health. It plays a dual role by inhibiting muscle protein breakdown and stimulating muscle protein synthesis, helping to maintain a healthy balance crucial for muscle growth and maintenance

This decrease in muscle protein breakdown and increase in muscle protein synthesis sounds pretty anabolic to me regardless of what shape you are in. With the immunity, gut health, brain boosting, all being possibilities of being improved along with muscular benefits, I find it definitely worth giving a couple months of use for myself. But yes I agree that it is less promising without a lot of testing on more healthy and fit adults.
 
Well besides the slabs of muscle popping my skin tight there is not much happening on week one...

Ha okay joking aside, I do think I am getting faster recovery.
I feel some mental sharpness which maybe enhancing my strength just slightly, almost identical to a good dose (600mg I think) of alpha-GPC pre-workout.
The combination of these two effects looks like a promising start but could as equally be placebo that dies away soon, as it is could be early improvements that lead to more effects down the road...
I feel good though once again a very similar feeling to alphaGPC or other some other proven cognitive enhancers.
 
Week 2 very similar to week 1 but more pronounced.

Definitely is improving my mood, enhancing my brain in such a way as I can more confidently say it is increasing my strength but once again I compare this to a good dose of alpha-gpc or caffeine (possibly combined) but certainly not to a steroid.

The recovery is up for sure which has me able to perform better and not slack any on my cardio.

I am putting weight on but I have been bigger (much bigger when on trest+dhb) I am very close to my normal max retain-able size with only TRT. I did not add protein shakes but think I have upped my protein and calories some with more fish and/or eggs than I had been eating.

Seemingly less fat as I have been able to burn more off with the enhanced recovery and energy(brain enhanced energy not a stimulated feeling).
 
Weight is still rising.

Definitely at my max off gear size and close to my top strength (prob at my top strength) for being this size and no anabolics (h-drol 50mged at same size gave me about 5 more db pounds and that was one of my go to supps for strength)

Forgot to mention and feel it's worth noting that I take the full dose all with my morning meds/supplements shortly upon waking. If I skip my morning workout and do it in the afternoon, I see no difference. The mental enhanced feeling seems to stay all day but may wear off by night time as it definitely doesn't interfere with sleep which some brain boosters can.
 
Just keeping it going with this.

Nothing has really changed since the last updates except my excitement about what maybe coming is growing.

I expected it to help me ease my weight back up but it hopped back in just a couple weeks with what seems to be an enhanced strength from what I can normally obtain at this size.

Excited to see what this coming week brings as I may hit some PRs for only TRT which I didn't quite expect but was sure hoping for just figured it may take till month 2 or 3
 
Weight is still up but probably leveled out as mentioned I am around my max.

Strength is up on pretty much everything.

I had some passed damage to one shoulder and am hitting some PRs on curls and rows. Close to my max on presses but could only be the shoulder stopping it from being better.
 
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Things seem to have stalled but if they hadn't I would of thought it was laced with a hormone. I got sick and missed almost a week of worthwhile training and eating etc but didn't feel too set back from that as I am back on my routine and seem to be returning to a good state

Been thinking that this product seems to do for me what creatine is said to do with both my strength and brain yet I can actually feel it working. I am a non or low responder to creatine so find it's effects much more subtle.
 
As mentioned last post things stalled and I couldn't tell if it was a stoppage of benefits or just a normalization?

Anyways will be taking December off but plan to try again mid January to see if it can be cycled or if I was just at a loss and responded too good the first round etc
 
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