I still think aromasin and all anti e's should be taken daily at smaller doses opposed to EOD or E3D. I'd say for 220mg test you should try 5mg aromasin ED. Use a slinpin and cut the tip off for accurate measurments. If thats your hrt and you plan to stay on aromasin long term with it then after about a month id just get an estradial test from directlabs. $50 and you'll always know your dose and not have to worry about it again. Im gonna be cruising for a while on 350-375mg test along with other compounds that dont convert to estro like primo,eq,etc.. and at 10mg ED my estradial was at 26 which is perfect. When i go back to regular hrt of 150-200mg test per week i plan to run 5mg ED and im assuming results will be similar but im still gonna dish out the $50 to find out for sure.