Some bad lipid panel results. Is it my AI? Diet? What?

[loot]

My lipid panels are all over the place. I'm getting an LDL-P, or NMR Lipoprofile. My Dr says this is the only one that actually tells you if you're in trouble. The LDL-C and the LDL:HDL ratio is just an indicator or a calc.

I suspect the keto diet I'm doing may be a problem. I'm probably eating too much protein to be in full ketosis anyway.

TRT:

80mg test cyp EW
.5mg Anastrazole EW, 24 hrs after Test injection.

LIPID PANEL:

Cholesterol, Total 315 HIGH (range is 100-199 mg/dL)

Triglycerides 56 (0-149 mg/dL) - - So this is GOOD NEWS! Low risk of cardiovascular disease.

HDL Cholesterol 71 (>39 mg/dL)
According to ATP-III Guidelines, HDL-C >59 mg/dL is considered a negative risk factor for CHD. - - So this is GOOD NEWS! Low risk of cardiovascular disease.

VLDL Cholesterol Calc. 11 (5-40 mg/dL) - This is GOOD NEWS! Low risk of cardiovascular disease.

LDL Cholesterol Calc. 233 HIGH (0-99 mg/dL) - BAD NEWS...

My C-Reactive Protein is .8 mg/L (range is 0-3.00) - This is GOOD NEWS! Low risk of cardiovascular disease.

My Apolipoprotein-B is 145 , (range is 0-70) - REAL BAD...? Way over range anyway.

Anyone know anything about this?

 

[chemical engineer]

315 is troubling! The question is if you have a high risk of LDL small particle! I got a boston heart done and I have the high risk. He jakes up my statin and wanted me to take niacin! I have read and heard that cholesterol is 75% genetic and 25% diet and lifestyle .

 

[loot]

315 is troubling! The question is if you have a high risk of LDL small particle! I got a boston heart done and I have the high risk. He jakes up my statin and wanted me to take niacin! I have read and heard that cholesterol is 75% genetic and 25% diet and lifestyle .

It is high, huh? My ratio is 4.058 however.
Mayo clinic article;
"According to the American Heart Association, the goal is to keep your cholesterol ratio 5-to-1 or lower. An optimum ratio is 3.5-to-1"

I asked my Dr about large fluffy vs. small dense LDL and she said LDL_P (the number of LDL particles in the blood) was the thing that matters.

I guess I'm not such a good Google doctor???? I don't understand it but I want to stay on T and an AI even if not Anastrozole.

 

[killroy]

It is high, huh? My ratio is 4.058 however.
Mayo clinic article;
"According to the American Heart Association, the goal is to keep your cholesterol ratio 5-to-1 or lower. An optimum ratio is 3.5-to-1"

I asked my Dr about large fluffy vs. small dense LDL and she said LDL_P (the number of LDL particles in the blood) was the thing that matters.

I guess I'm not such a good Google doctor???? I don't understand it but I want to stay on T and an AI even if not Anastrozole.

aromasin is said not to effect lipids. but with that small dose of arimidex .5mg once a week and only 80mg of test, I highly doubt it's having a substantial impact on your lipids. do you have baseline lipid values before starting trt?

 

[Cobraman]

Keto diet or any low carb diet is beneficial to cholesterol numbers. Many doctors are more into the ratio than the actual numbers. If your HDL is good the other numbers are somewhat less important. Did you have an Lp-a number? That is the so called heart attack cholesterol. It does seem strange to have so high an LDL.

There is a book called the Great Cholesterol Con that is a collection of studies on cholesterol and it is the author's opinion that if HDL is high, other numbers do not matter much.

 

[pesty4077]

You total cholesterol is, for most people, much too high. Your LDL (low density lipoprotein) is higher than your total cholesterol should be. Normal readings are as follows:
Total cholesterol: lower than 200 mg/dL
LDL cholesterol: lower than 100 mg/dL
HDL cholesterol: greater than 40 mg/dL
HDL is high density lipoprotein or the "good" cholesterol. LDL is the "bad cholesterol. Your "bad" cholesterol is way too high. It can cause plaque buildup on artery walls. You are in danger of arterial blockage by cholesterol build up in your arteries. Particularly the arteries in your heart. You are beyond the point where diet alone will correct your condition in a reasonable amount of time. Your doctor may very well want to prescribe medication for you to help lower your total cholesterol level.

Apolipoprotein B and apolipoprotein A-I: risk indicators of coronary heart disease and targets for lipid-modifying therapy - Walldius - 2004 - Journal of Internal Medicine - Wiley Online Library