Steroid Receptor Burnout

[John99Test]

Hi

 

[emeric delczeg]

How is it possible that year long steroid cycles can produce gains still when their is steroid receptor burnout? That is, they become so saturated that you stop growing. How do the pros stay on full time and still make gains? I believe my receptors are burned out and the only way to clear them is to go off the gear for a while. Which I really dont want to do haha. Not until the summer is over. Is there any other way to free up my receptors? Switch gear maybe? What do you guys think? I dont know too much about receptors etc. Thanks.

What are you taking and how much?

 

[Ness]

Sounds to me like you have reached a plateau. Not a receptor burnout, if there is such a thing? Have you considered a revision of more important factors such as diet, training methods, and rest? Gear is just a boost, not a regiment. Just food for thought. Good luck!

 

[Pekkerwood]

The so called "Receptor Burnout" is probably not the issue. Diet, Sleep, training should be making 90% of your gains. We focus on the "supplement" side as being the controlling factor for some reason, I guess its natural to do. Look at the larger factors first, diet, training, recovery, then the supplements last.

If you agree with the premise that "supplements" are 10% of the answer and you tweak your "supplements" 20%, may be making a 2% total differnece. I know it does not work that way, just pointing out that the first thing we normally look at is usually the last place we should look.


Jeff

 

[b-boy]

Ok I am going to get flamed but I have been on a dose of 500mg Test Ent for a six month period, then I upped it to 750mg per week for the next 6 months. Total = over a year now cycle. Blood Tests are all OK. 1mg Arimidex EOD, 1mg Propecia ED. I am 6ft, 235bs. bf around 11%. Oh I also have done 3 short 3wk cycles of Dbol in between.

I think you may be right, my diet needs some fine tuning, rest is good.

just a question but why stay on so long??

 

[Big Bapper]

Ok I am going to get flamed but I have been on a dose of 500mg Test Ent for a six month period, then I upped it to 750mg per week for the next 6 months. Total = over a year now cycle. Blood Tests are all OK. 1mg Arimidex EOD, 1mg Propecia ED. I am 6ft, 235bs. bf around 11%. Oh I also have done 3 short 3wk cycles of Dbol in between.

I think you may be right, my diet needs some fine tuning, rest is good.

Whats your HDL like after running Arimidex for 1 year.

 

[b-boy]

ha you know who is kicking your ass bro?

this little guy named SHBG

first rule in war...... know your enemies!

 

[b-boy]

what can I do about it bro?

first thing i would do is hit the search button been talked about before bro.

free up more test and you will grow!

 

[aesop]

first thing i would do is hit the search button been talked about before bro.

free up more test and you will grow!

More test and androgens have been shown to decrease shbg. It seems estrogen levels have more impact on shbg. As increasing testosterone will decrease shbg. Also no such thing as steroid receptor burnout, but you will reach a point of diminishing returns. eg there is a point where taking more will not and can not yield more gains.

 

[b-boy]

More test and androgens have been shown to decrease shbg. It seems estrogen levels have more impact on shbg. As increasing testosterone will decrease shbg. Also no such thing as steroid receptor burnout, but you will reach a point of diminishing returns. eg there is a point where taking more will not and can not yield more gains.

actually i wish i wouldn't have posted the post about SHBG! first thing you need to check is your diet and training, about 97% of the time people are not taking in enough calories for continued growth, and you can't train like jane fonda and expect to grow either, you best be in the gym pushing yourself daily and lifting some heavy slag iron bro.

now about the SHBG heres a pretty good read from a thread a while ago
http://www.professionalmuscle.com/forums/showthread.php?t=2296&highlight=SHBG take what you want from it but diet and training first!

 

[buldog9]

Try some DHEA 25mg morning 25mg night. Do a search on it, there is good info,after your on gear a while your body stops producing it and cortisol of which you need a little to grow. Its like estrogen you need a little to grow but to much is bad. There for try Humanofort 1000 mg per day for first month [order it from Herb], if you decrease it and gains stop then go back up. Im 52 [I have to take 9000mg per day]and have been on gear almost 2 years. After about 4 months No mater how much I increased [And I took a lot]gear or changed gear or dieted or worked out I had no gains. I searched and looked and read every thing I could.I found receptor down grading is a mith. When I hit on the above protocol I started growing and strength increased. In 12 days my bench went up 15 lbs. Now I grow with minimal doses of gear. !0 mg per day d-bol,10mg winny and 10 mg anavar. I have been on orals for 3 months with no sides and liver values are fine. Before I get flamed Im not condoning orals for every one just for me.

 

[b-boy]

also why stay on year round, you still haven't answered that question? if you were able to continue growing of AAS year round by staying on year round there would be some 500 pound bodybuilders walking around now wouldn't there? you body has negative feedback loops that are pretty damn smart and very effective at keeping things in balance

so why stay on for a year straight thinking your going to grow for a year straight, some of the best elite genetic bodybuilders can't do it so why could you??

O yea im not flaming you just questioning your methods thats all.

 

[OuchThatHurts]

More test and androgens have been shown to decrease shbg. It seems estrogen levels have more impact on shbg. As increasing testosterone will decrease shbg. Also no such thing as steroid receptor burnout, but you will reach a point of diminishing returns. eg there is a point where taking more will not and can not yield more gains.

Yes, but at what point is that? 100mg per day? 200mg? I guarantee you that's it's much higher than what he's taking.

I'd drop the Arimidex myself. You're estrogen is probably too low.

And what the heck is receptor burnout??? Androgen receptors aren't fixed and they can't get "tired". The action of the receptor to the HRE and the subsequent transcription is a very complicated process. It's a series of chemical reactions on a very small scale. Chemicals do not get tired - only the amounts of chemicals can change and as we already know, androgens increase receptors.

 

[OuchThatHurts]

Receptor Burnout was a poor choice of words. What I meant was that the receptor sites were saturated so much that I could no longer make gains.

What do you mean? That your skeletal muscle was so soaked with testosterone that your cells could no longer carry AR messenger RNA?

I'm not trying to be an ass but maybe you should just eat right, train hard, and forget about, don't even think about, receptor sites and RNA and transcription and either get off the drugs totally or switch up your program to something else entirely. You hit a plateau. Everyone does. Start changing up your program until you start seeing signs of progression - size, strength, whatever.

 

[Turbomaster]

clen seems pretty effective for cleaning receptors.

 

[OuchThatHurts]

clen seems pretty effective for cleaning receptors.

WHAT?!?

 

[KillerStack]

WHAT?!?

LOL I want to hear this too

 

[VNV]

WHAT?!?

Gotta love public forums! My favorite replies however are when someone comes in saying, "Yeah, my doctor said... but...," and then everyone offers their opinion on the matter--like they're in a better position to make recommendations concerning health than one's own physician.

 

[emeric delczeg]

Try some DHEA 25mg morning 25mg night. Do a search on it, there is good info,after your on gear a while your body stops producing it and cortisol of which you need a little to grow. Its like estrogen you need a little to grow but to much is bad. There for try Humanofort 1000 mg per day for first month [order it from Herb], if you decrease it and gains stop then go back up. Im 52 [I have to take 9000mg per day]and have been on gear almost 2 years. After about 4 months No mater how much I increased [And I took a lot]gear or changed gear or dieted or worked out I had no gains. I searched and looked and read every thing I could.I found receptor down grading is a mith. When I hit on the above protocol I started growing and strength increased. In 12 days my bench went up 15 lbs. Now I grow with minimal doses of gear. !0 mg per day d-bol,10mg winny and 10 mg anavar. I have been on orals for 3 months with no sides and liver values are fine. Before I get flamed Im not condoning orals for every one just for me.

If he takes the Humanofort than is no need for DHEA, Ron Coleman has been taking the Humanofort for 9 years non stop.

 

[emeric delczeg]

I will take your advice. This is obviously a plateau and I will change some things around. I will change a lot actually. Thanks alot. I appreciate your advice.

Is not plateau, you andocrine system is burned out. Take the Humanofort and you will be very happy.