Steroids and Dementia

[Thappy]

try some 5htp

 

[LoweRider]

I feel steroids have a positive effect on me when I take them. I'm more assertive/confident, and the sex drive/erection boost is something I'm always happy with (so is my wife). As soon as I'm finished with my government job next year, I'm going to be doing blast/cruise permanently.

 

[Cv215]

Ive been on aas non stop for the last six years. Way more time has been spent cycling than cruising. I live a very healthy life. I always eat well, get more then enough rest, dont drink or do drugs.

However, i absolutely feel like aas has impacted my cognitive abilities. I don't feel as sharp. My main issue is with communication. Ill have in my head what i want to say, and in my head it will feel perfectly clear, and then as soon as i start to talk its like the words disintegrate. Sometimes ill just freeze up in the middle of a sentence. Or ill be in the middle of trying to explain something and I'll have to stop and pause for a very long time to rebalance everything in my head. I'm constantly doing this and its extremely embarrassing and makes me look and feel like a moron. Its like I'm having trouble putting my thoughts into words. Sometimes this can be normal for people who are trying to explain a difficult subject thay they arent familiar with. For me its happening with the most basic things. Ill try to tell a story and its like i have trouble keeping the order of everything. I end up all over the place and a lot of times people will just look at me like wtf arr you trying to say. Spit it out!

I'm only 34, but it's strange because my dad had a severe brain trauma from a motorcycle accident. He developed these same exact issues so it kind of makes me wonder if i had some type of predisposition to it.

I really do think aas has had a negative effect on my brain. It may not effect everyone like this though. All i know is before i started using gear my brain worked great.

I definitely abused a lot of tren over the years. That shit used to make my brain feel like it was melting. Not everyday on it was bad though which is why i was able to tolerate it for quite a while.

Im done using heavy cycles though. Trt, a few units of hgh and maybe one additional compound added in so often is all in sticking with from here out. Ive learned that you cwn still make great progress on a small amount of gear.

 

[bigains]

I have been studying about correlations of steroid use (or abuse, despite my username) and dementia, namely Alzheimer and i am really afraid i could suffer from this in future.

I feel that after 10 years of long use of steroids my brain is not the same anymore: i forget often, it's harder to think and i am always depressed.

I am software engineer and i find really difficult to perform on my job, it's really hard to be on the computer all the day trying to understand new technologies, algorithms and i find it really hard to learn.

I have have story of party drug abuse (cocaine and MDMA) but i don't use anymore, i am clean. Last 2 years i was also on medications for depression, but i am quitting these medications for good.

With 31 years old and after competing in bodybuilding and have a lot of parties i am really focused in just being healthy, being lean and focus on my career, however i will need to use steroids for the rest of my life since i have been using nonstop since 2010...

I had to let it out, thanks for reading and please feel free to share your stories.

Please see the following article: https://www.mcleanhospital.org/news...use-can-lead-significant-brain-structural-and

Check out Leo and Longevity, redit, blog, YouTube videos. I have made some helpful changes to my supplementation after watching his videos and reading his blog in its entirety. This has really helped with brain fog, mood, energy level, and anxiety. At 40 years old working in healthcare, being mentally sharp and stress resilient is quite important. I dabbled with prohormones at 17 then starting anabolics at 22. I have had some problems with addiction on and off as well. I have been completely sober for the last 8 years. I have been on an SNRI for a long time, blocking the sert transporter has a profound effect on increasing neurogenisis and as a result neuroplasticity, and I am on TRT because I could never recover adequately from my abuse of my body in my early 20s, even being completely off multiple times with pct for as long as two years at once. Some things I have slowly implemented that have helped with my mental clarity, energy level, and anxiety. I bought an auto adjusting cpap off wish.Com for around 300 dollars as I was waking up dizzy, disoriented, and even gasping at times, my rbc count had also been slightly elevated for a couple of years. I stopped using any form of ai's, estrogen is neuroprotective and improves cognition. I stopped using any form of 5ar inhibitor as the enzyme is neccisary to produce a few very important neurosteroids that promote neurogenisis, regulate mood, anxiety, ect.... . I started adding supplements for my mood, anxiety, energy, and mental clarity, one at a time to assess my response, and each addition gave me an improvement. 25mg dhea once then twice daily which is a full replacement dose. Dhea usually decreases on long term trt. Pregenolone decreases as well, it was helpful for my mood but any dose caused too much bloat so I cut it. 10mg of trans scrotal progesterone cream once a day, for the higher conversion directly to 5a-dihydroprogesterone in the scrotal skin, which can then convert into allopregenolone more directly with less circulating progesterone; this has given me a mood boost and has greatly reduced my anxiety. Long term trt stops the Testicles from producing progesterone, oral micronized progesterone at 8mg twice daily provides a normal male replacement dose, all I could easily find on Amazon was transdermal progesterone so I went with it applied to scrotal skin because of the high level of 5ar enzime activity in scrotal skin. Taking 5ar inhibitors shut down the bodies ability to produce important neurosteroids like allopregenolone and others, and can affect cognition, mood, and anxiety as well. I added one 0 size cap, about 500mg, I am very sensitive to huperzine-a which is somewhat uncommon, of gorilla mode stim Pre workout each morning, it contains huperzine-a for acetylcholine reuptake inhibition for mental clarity and some neuroprotection by providing a low level reversable blockade of the nmda receptor, it also contains kanna, tyrosine, and N-Phenethyl Dimethylamine Citrate. A normal dose is 3.7g. This has greatly improved my mental clarity and endurance at the expense of a slight increase in anxiety, which is alleviated by the other sups I take. One cap 120mg of ginko baloba as an acetylcholine esterase inhibitor, brain blood flow increase, and brain antioxidant, 500mg of bacopa monnieri once daily and sometimes I take another 500mg in the evening if I am feeling stressed. The bacopa provides a noticeable mood boost and anxiety reduction as well. I take 5mg of low dosed naltrexone each night to lower inflamation, and improve pain control while I am awake, among other benifits related to IBS. I also take 20mg of melatonin each night as a brain antioxidant, and sleep aid. I take a bunch of other health related supps as well as medications, mostly related to general health, inflamation, and cardiovascular health, but it is too lengthy for me to want to get into all that.
Check out Leo's Reddit, blog and YouTube videos. Some people hire him for consultations as well for cognitive optimization. I have learned enough from his videos, blog and reading some related research on my own to add some helpful supps to address some of the issues I have had related my endocrine system FUBAR and past issues.

Reddit - Dive into anything

www.reddit.com

I have also learned a lot from reading ergo-log articles, Derrick the creator of moreplatesmoredates.com has a lot of good information on his websight and on his YouTube vids as well. Good luck.

 

[opietaylor]

you guys are thinking of this in the wrong pathways rather than direct effects on the brain itself it happens indirectly. steroids cause hardening of the arteries for some this will lead to a heart attack for other the arteries in the neck can harden ultimately leading to vascular dementia. all the shit posted above may be great for brain fog or whatever but once blood flow starts getting restricted its game over and good chance by the time you yourself realize your forgetting shit or get lost while out driving in your own town it it is way way to late. control BP at all costs.

 

[SlickNYC]

Check out Leo and Longevity, redit, blog, YouTube videos. I have made some helpful changes to my supplementation after watching his videos and reading his blog in its entirety. This has really helped with brain fog, mood, energy level, and anxiety. At 40 years old working in healthcare, being mentally sharp and stress resilient is quite important. I dabbled with prohormones at 17 then starting anabolics at 22. I have had some problems with addiction on and off as well. I have been completely sober for the last 8 years. I have been on an SNRI for a long time, blocking the sert transporter has a profound effect on increasing neurogenisis and as a result neuroplasticity, and I am on TRT because I could never recover adequately from my abuse of my body in my early 20s, even being completely off multiple times with pct for as long as two years at once. Some things I have slowly implemented that have helped with my mental clarity, energy level, and anxiety. I bought an auto adjusting cpap off wish.Com for around 300 dollars as I was waking up dizzy, disoriented, and even gasping at times, my rbc count had also been slightly elevated for a couple of years. I stopped using any form of ai's, estrogen is neuroprotective and improves cognition. I stopped using any form of 5ar inhibitor as the enzyme is neccisary to produce a few very important neurosteroids that promote neurogenisis, regulate mood, anxiety, ect.... . I started adding supplements for my mood, anxiety, energy, and mental clarity, one at a time to assess my response, and each addition gave me an improvement. 25mg dhea once then twice daily which is a full replacement dose. Dhea usually decreases on long term trt. Pregenolone decreases as well, it was helpful for my mood but any dose caused too much bloat so I cut it. 10mg of trans scrotal progesterone cream once a day, for the higher conversion directly to 5a-dihydroprogesterone in the scrotal skin, which can then convert into allopregenolone more directly with less circulating progesterone; this has given me a mood boost and has greatly reduced my anxiety. Long term trt stops the Testicles from producing progesterone, oral micronized progesterone at 8mg twice daily provides a normal male replacement dose, all I could easily find on Amazon was transdermal progesterone so I went with it applied to scrotal skin because of the high level of 5ar enzime activity in scrotal skin. Taking 5ar inhibitors shut down the bodies ability to produce important neurosteroids like allopregenolone and others, and can affect cognition, mood, and anxiety as well. I added one 0 size cap, about 500mg, I am very sensitive to huperzine-a which is somewhat uncommon, of gorilla mode stim Pre workout each morning, it contains huperzine-a for acetylcholine reuptake inhibition for mental clarity and some neuroprotection by providing a low level reversable blockade of the nmda receptor, it also contains kanna, tyrosine, and N-Phenethyl Dimethylamine Citrate. A normal dose is 3.7g. This has greatly improved my mental clarity and endurance at the expense of a slight increase in anxiety, which is alleviated by the other sups I take. One cap 120mg of ginko baloba as an acetylcholine esterase inhibitor, brain blood flow increase, and brain antioxidant, 500mg of bacopa monnieri once daily and sometimes I take another 500mg in the evening if I am feeling stressed. The bacopa provides a noticeable mood boost and anxiety reduction as well. I take 5mg of low dosed naltrexone each night to lower inflamation, and improve pain control while I am awake, among other benifits related to IBS. I also take 20mg of melatonin each night as a brain antioxidant, and sleep aid. I take a bunch of other health related supps as well as medications, mostly related to general health, inflamation, and cardiovascular health, but it is too lengthy for me to want to get into all that.
Check out Leo's Reddit, blog and YouTube videos. Some people hire him for consultations as well for cognitive optimization. I have learned enough from his videos, blog and reading some related research on my own to add some helpful supps to address some of the issues I have had related my endocrine system FUBAR and past issues.

Reddit - Dive into anything

www.reddit.com

I have also learned a lot from reading ergo-log articles, Derrick the creator of moreplatesmoredates.com has a lot of good information on his websight and on his YouTube vids as well. Good luck.

Damn bro thats some list of pills. Great info btw as I feel I’m suffering from onset of dementia. Had no idea it could be from tren but I have used slot in my day. Do you have a pill organizer? I’m assuming you need one. I’m actually going to look into the products you listed on Amazon. You did all the homework for me as I woke up today planning on finding supplements for my issues which are similar to yours. Which SNRI are you taking and was that the first you tried?

 

[bigains]

Thanks, glad my experience could be helpful. I don't use an organizer, I just keep the bottles in a drawer, and take them out one at a time. I take a lot of fish oil, some vitamins, and other health related supplements, blood pressure meds, and cholesterol meds ect.... They all would never fit in an organizer. The only SNRI I have used has been venlafaxine ER, it works ok so I have continued to use it.

 

[emeric delczeg]

Normal (optimal) levels = better cognitive function. High out of range effects negatively the neurons.​

​

 

[emeric delczeg]

Damn bro thats some list of pills. Great info btw as I feel I’m suffering from onset of dementia. Had no idea it could be from tren but I have used slot in my day. Do you have a pill organizer? I’m assuming you need one. I’m actually going to look into the products you listed on Amazon. You did all the homework for me as I woke up today planning on finding supplements for my issues which are similar to yours. Which SNRI are you taking and was that the first you tried?

You don`t have dementia yet, just stop using the tren and don`t let your test levels get to high out of range for to long of period (years) you can regenerate the neurons, ether with some supplement that helps to keep your NGF level in good range or just take natural NGFs.

NGF is involved primarily in the growth, as well as the maintenance, proliferation, and survival of nerve cells (neurons). In fact, NGF is critical for the survival and maintenance of sympathetic and sensory neurons, as they undergo apoptosis in its absence.[5] However, several recent studies suggest that NGF is also involved in pathways besides those regulating the life cycle of neurons.

 

[Brock456]

Normal (optimal) levels = better cognitive function. High out of range effects negatively the neurons.​

​

what are “normal levels” though? If we are going by the range, I think it’s like 247-850. Also what may be normal for me might not be normal for you, and vice versa.... then take into account age, etc.

 

[emeric delczeg]

what are “normal levels” though? If we are going by the range, I think it’s like 247-850. Also what may be normal for me might not be normal for you, and vice versa.... then take into account age, etc.

For over 50 years 600 to 800, for younger up to 900.

 

[Matsuo Munefusa]

For over 50 years 600 to 800, for younger up to 900.

Emeric, while you’re here can I ask your opinion with adding primo into a 10-20mg test per day approach. Primo 400-700mg/week. For sake of conversation let’s say for a guy in his 40s who isn’t wanting anymore size but wants to keep recovery from training at a high rate.

 

[Rumpwrangler]

You mentioned cocaine And MDMA abuse. I can tell you for certain that it took my brain a few years to recover from MDMA and ecstasy abuse. And I was depressed often during that time. And I’m not the type to get depressed naturally. But I also remember major brain fog and trouble learning during my recovery time.

That was 20 years ago for me. I didn’t touch anabolics until 11 years ago at age 30 and I haven’t suffered from any of the issues mentally/psychologically that I did from abuse of ecstasy/MDMA. My point is that your issues may be a result of rec drug usage and not steroids.

 

[cage99]

Only thing AAS did for me negatively is give me sleep apnea. Just from the added neck tissue buildup throughout the years. Got me a solid 22.75” taped neck!!!! Been using em now for 17yrs and I’m still sharp as a tack! As for the sleep apnea I just use a CPAP.

Cage

 

[Elvia1023]

This is a very complex subject. As Jeff posted see a specialist. I am not going to bother going into great detail because there are literally 1001 different things but I will list some of the things I do to prevent a decline in cognitive functioning.

Keep my mind busy. Occasional puzzles such as sudoku.
Adequate sleep.
Avoiding party drugs (used to party a lot in the past).
Breaks from blast doses. True TRT between cycles. Avoiding neurotoxic drugs and when using certain aas adding others to combat their neurotoxic effects (test and dht with nandrolone for example).
Drinking lot's of water.
Avoiding stressful situations when possible.
Ginkgo Biloba, Bacopa Monnieri, Fish Oil (high EPA), Multi Vitamin (B and D etc), Curcumin and Synthetine.
High anti-oxidant foods such as berries (lot's of blueberries).
85% dark chocolate, coffee, greens etc.

 

[Ruhlfreak55]

Key is to stay away from compounds like tren that exhibit neurotoxic effects

Have periods of normalization (proper TRT for most guys), sleep properly

Things like fish oil, magnesium, Vit D; should all be part of one's daily regimen

There's no bloodwork to check NT irregularities, and unless you had a pre AAS baseline, even a PET scan won't illustrate changes in brain activity. Prob something that should be talked about more; especially in the coming generations that have some of the highest diagnosis rates for mental health issues

Steroids certainly won't help those issues

Uhm....what?!

 

[Fat Boy]

Dihexa

also very low dose DNP (like 2-3mg a day)

google it

 

[SlickNYC]

Dihexa

also very low dose DNP (like 2-3mg a day)

google it

What about those thing? DNP at 2-3mg per day? The DNP used to burn fat? Can treat the dementia?

 

[Fat Boy]

What about those thing? DNP at 2-3mg per day? The DNP used to burn fat? Can treat the dementia?

the dnp at that dose is used for neuroprotection, not fat loss

 

[emeric delczeg]

Emeric, while you’re here can I ask your opinion with adding primo into a 10-20mg test per day approach. Primo 400-700mg/week. For sake of conversation let’s say for a guy in his 40s who isn’t wanting anymore size but wants to keep recovery from training at a high rate.

Well you can maintain your size with 10mg per day or even gain some muscle, depending on your training and diet, I have been gaining some size lately on 10mg at age 68, but I have been working out almost the same way when I was competing. You can add the primo if you want but is not necessary, the training and the diet will help the most to maintain or gain muscle.