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- Jun 4, 2002
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I've long thought stress was a killer. Plenty of known effects - balding (ego killer), heart etc. And the immune system is frequently downgraded and most of us have experienced how stress can affect your physique, but maybe there will soon be evidence of it shortening our life times. IronMike
Stop stressing: you'll grow old before your time
By Benedict Carey and Jacqueline Maley
December 1, 2004
Some stressful events seem to turn a person's hair grey overnight.
Now a team of researchers has found that severe emotional distress may speed up the ageing of the body's cells at the genetic level. The findings are the first to link psychological stress so directly to biological age.
The researchers found blood cells from women who had spent many years caring for a disabled child were, genetically, about a decade older than those from peers who had far less experience of this. The study, which appears in Proceedings of the National Academy of Sciences, also suggests that the perception of being stressed can add years to a person's biological age.
"It's fascinating research," said David LeCouteur, a specialist on ageing at Sydney's Concord Hospital. "It shows how environmental factors might lead to biological ageing."
In the experiment, researchers from the University of California analysed white blood cell samples from 58 young and middle-aged mothers, 39 of them caring for a child with a chronic disorder such as autism or cerebral palsy.
The study found that the longer the women had taken care of their child, the shorter the length of a piece of DNA called the telomere. Change in telomere length over time is thought to be a rough measure of a cell's age.
The researchers also gave the women a questionnaire, asking them to rate how stressed they felt. The women who felt they were under heavy stress also had significantly shortened telomeres, compared with those who felt more relaxed - whether they were raising a disabled child or not.
Professor LeCouteur said the link between short telomeres and ongoing stress was "an interesting hypothesis" but the research did not prove the correlation beyond doubt. "The high stress seemed to be in older, fatter women but it may be that older women are more likely to have shorter telomeres and sick children."
Stop stressing: you'll grow old before your time
By Benedict Carey and Jacqueline Maley
December 1, 2004
Some stressful events seem to turn a person's hair grey overnight.
Now a team of researchers has found that severe emotional distress may speed up the ageing of the body's cells at the genetic level. The findings are the first to link psychological stress so directly to biological age.
The researchers found blood cells from women who had spent many years caring for a disabled child were, genetically, about a decade older than those from peers who had far less experience of this. The study, which appears in Proceedings of the National Academy of Sciences, also suggests that the perception of being stressed can add years to a person's biological age.
"It's fascinating research," said David LeCouteur, a specialist on ageing at Sydney's Concord Hospital. "It shows how environmental factors might lead to biological ageing."
In the experiment, researchers from the University of California analysed white blood cell samples from 58 young and middle-aged mothers, 39 of them caring for a child with a chronic disorder such as autism or cerebral palsy.
The study found that the longer the women had taken care of their child, the shorter the length of a piece of DNA called the telomere. Change in telomere length over time is thought to be a rough measure of a cell's age.
The researchers also gave the women a questionnaire, asking them to rate how stressed they felt. The women who felt they were under heavy stress also had significantly shortened telomeres, compared with those who felt more relaxed - whether they were raising a disabled child or not.
Professor LeCouteur said the link between short telomeres and ongoing stress was "an interesting hypothesis" but the research did not prove the correlation beyond doubt. "The high stress seemed to be in older, fatter women but it may be that older women are more likely to have shorter telomeres and sick children."