The best way that I found for me to ramp up my GH dose is to start out at 2 iu a day. You will be sleepy and have some water retention for a few weeks but not unbearable. Once the bloat and sleepiness dissipates you can then increase dose to 4 or 5 iu with no problem. Easy peasy. Just start at a low dose (2iu) wait for the sides to leave and then ramp up without any further increases in sides.