BB. One more question I will let this die Lol.
Thoughts?
*** Mods-feel free to delete delete the link if I’m not supposed to post that”
https://www.t-nation.com/diet-fat-loss/what-you-dont-know-about-your-thyroid
“What About Frontloading T4?
How much T4 does your body have in it after taking, say, 100 mcg of T4? Well, if it's your first dose, then about 100 mcg. Simple enough.
But when you're about 6 weeks into taking T4, when you swallow a daily dose there are already about a week's worth of earlier doses still in the body, still active!
So the effect of T4 doses will start out being only about 1/7th as strong as will be the case later. Even one or two weeks into the program, the effect will be only partial.
For many drugs with a long duration of action like T4, frontloading is a way to account for this. In order to promptly get body levels to where they should remain, on Day 1 an extra amount is taken which corresponds to the above buildup. But T4 is a drug you absolutely don't want to overdose. You don't want to take a week's worth of T4 on Day 1 even though, most likely, it's about the correct amount.
A good solution is to double dose T4 during the first four days of use. This brings levels to the steady state in about 5 days instead of a month.
T3 is fast acting and absolutely no frontloading compensation should be made.
So when using the above schedules for combining T3 and T4, double the T4 in the first four days, but keep T3 the same.”