TB-500 and the heart ?

[specter]

So i was reading up on TB-500 and found data from diff stuides on rats etc and it looks like it can partly fix a damaged heart, now my heart wasent damaged really but i had sligthly lowered function and EF about 3 years ago, cut to this year and my heart is fine its pumping at full capacity, EF is now normal and the cardiologist commented that my heart was extremly elastic wich suprised him as normally people who used alot of roids has more stiff hearts. I used alot of TB-500 these last couple years do to my elbows being fucked, could it be that TB-500 "fixed" my heart ?

 

[Ha.Ki.Beom]

What other variables changed? (eg telmisartan, dapagliflozin, cardio zone 2, reduction in doses, etc)

Yes the heart "stiffens" with the use of steroids, the contraction part gets really strong in juxtaposition to the relaxation - the diastolic part.

The opposite happens in endurance at the athletes - their contraction is weaker compared to the relaxation.

This creates asymmetrical cardiac function, characteristic of heart failure. Under the echo you see the heart beating completely 'wonky'.

Cardio zone 2 helps balances out cardiac function for us bodybuilders with strong contraction, so if you implemented zone 2 and reduced your anabolic load these past 3 years it could help explain.

There seems to be evidence of tb-500 with cardiac cell damage regeneration. (Steroids can cause apoptosis in hearts cells, through several pathways.)

There is also the component that the echo is operator dependent and the values of your EF can change according to who does the test. The sensitivity for function would be better viewed through strain echocardiography with speckle tracking, which allows the 3d mapping your heart and allows the echo to track the beating to better see the contraction and relaxation of cardiac muscles.

 

[KingOfSushi]

I used alot of TB-500 these last couple years do to my elbows being fucked, could it be that TB-500 "fixed" my heart ?

Unfortunately it’s impossible for any of us to answer this for you.

Sounds like it certainly didn’t hurt, though.

 

[specter]

What other variables changed? (eg telmisartan, dapagliflozin, cardio zone 2, reduction in doses, etc)

Yes the heart "stiffens" with the use of steroids, the contraction part gets really strong in juxtaposition to the relaxation - the diastolic part.

The opposite happens in endurance at the athletes - their contraction is weaker compared to the relaxation.

This creates asymmetrical cardiac function, characteristic of heart failure. Under the echo you see the heart beating completely 'wonky'.

Cardio zone 2 helps balances out cardiac function for us bodybuilders with strong contraction, so if you implemented zone 2 and reduced your anabolic load these past 3 years it could help explain.

There seems to be evidence of tb-500 with cardiac cell damage regeneration. (Steroids can cause apoptosis in hearts cells, through several pathways.)

There is also the component that the echo is operator dependent and the values of your EF can change according to who does the test. The sensitivity for function would be better viewed through strain echocardiography with speckle tracking, which allows the 3d mapping your heart and allows the echo to track the beating to better see the contraction and relaxation of cardiac muscles.

Nothing else changed in those years between first and second scan of the heart.

 

[TheOtherOne55]

Can you show the info you have here?
To my understanding, TB500 is the sythentic peptide fragment of TB4.
So there is TB500 and TB4 aaand TB4-frag.
TB4-frag is actually an oral peptide that has shown potential therapeutic effects related to healing the heart, primarily by reducing inflammation, preventing fibrosis, and promoting angiogenesis and cell survival after an injury.

JP is a fan of lots of TB4-frag when guys are running incredibly high doses. So just trying to check if you have it right. I personally have heard 0 info on TB500 and the heart...but have on TB4-frag.

 

[Siggy]

Your EF was only slightly compromised, so im not sure you can ascribe something remarkable happening and/or attributing it to TB500.

Have you been taking the same amount of HGH and steroids during this time frame?

As others asked, did you start taking BP meds during this time frame?

Did you do more cardio?

 

[specter]

Can you show the info you have here?
To my understanding, TB500 is the sythentic peptide fragment of TB4.
So there is TB500 and TB4 aaand TB4-frag.
TB4-frag is actually an oral peptide that has shown potential therapeutic effects related to healing the heart, primarily by reducing inflammation, preventing fibrosis, and promoting angiogenesis and cell survival after an injury.

JP is a fan of lots of TB4-frag when guys are running incredibly high doses. So just trying to check if you have it right. I personally have heard 0 info on TB500 and the heart...but have on TB4-frag.

I just googled tb-500 and heart and started looking

 

[specter]

Your EF was only slightly compromised, so im not sure you can ascribe something remarkable happening and/or attributing it to TB500.

Have you been taking the same amount of HGH and steroids during this time frame?

As others asked, did you start taking BP meds during this time frame?

Did you do more cardio?

Nothing changed
4iu of GH
Same dose of test 150mg test e
No meds was added or pulled out
Cardio didnt change as i dont really do any "cardio" other then 3 10mins walk a day.


Edit:
Lithium was put in at the start of this year and Lamotrigin, but dont think they do anything good for the heart really.

 

[Siggy]

Nothing changed
4iu of GH
Same dose of test 150mg test e
No meds was added or pulled out
Cardio didnt change as i dont really do any "cardio" other then 3 10mins walk a day.


Edit:
Lithium was put in at the start of this year and Lamotrigin, but dont think they do anything good for the heart really.

Thats all that your on? I thought i just saw a picture of you looking massive.

 

[Sectør]

the tb500 studies do show some promising literature on heart repair.

The issue though… is that these studies are done on mice and rodents, which makes them unreliable and maybe even unusable because they may not carry over to humans the same way.

Wish there was better human clinical data on this because it does open up an interesting train of thought

 

[specter]

Thats all that your on? I thought i just saw a picture of you looking massive.

Yeah, must be an old pic, atm im very small but with an ok BF%
havent been able to really train these last years cus of my elbow issues.
Edit:Oh prob my back pics, yeah those are couple years old.

 

[specter]

the tb500 studies do show some promising literature on heart repair.

The issue though… is that these studies are done on mice and rodents, which makes them unreliable and maybe even unusable because they may not carry over to humans the same way.

Wish there was better human clinical data on this because it does open up an interesting train of thought

Would love if they put some more research into BPC-157 as well, but as far as i can understand, since its naturally occuring in our stomach there isnt much $$$ to gain from it.