I have read a Russian pharmacology study stating that some athletes needed 4x the dose of AAS to get the same effect as the best responders. I may be one of the poorer ones.
I believe I'm a poor responder also. I think It gets worse the older I get too.
Example: For my last cycle I started with 500mg Test E & 250mg Deca per week, along with 30mg dbol/day. By the 4th week I was up 21lbs(213lbs)! After 2 more weeks at same dosage (without the dbol), my BW was stuck at same weight, despite stuffing my face, training well/consistent. So I increased the frequency to every 5 days, at same dosage...nothing, not 1 more pound!. So I used same dosage every 4 days, still no response (now week #8) At this point I increased the dosages to 750mg & 300mg respectively. After 3 shots at these dosages, I gained 2 lbs (215lbs). By this point I had added 75mg/day tbol (it was Bangor Labs tbol, so It could have been bunk) & I upped the Deca to 400mg. So I was taking 750mg Test E & 400mg Deca along with the tbol every 4 days!!! Final outcome after 12 wks?!...I got up to 217lbs (gain of 25lbs) I'd say about 5lbs of it are fat!
Now some may say..."wow dude, that's really good" but look at my dosages!!! And mind you, I was also using 5iu GH 5x/wk!!!
Already I'm down to 210lbs (last shot was on the 1st)
So bottom line, I doubt most people on this board have to go this high on their dosages to get these kind of gains!!!