Throwing out this idea: Progesterone receptor antagonists/SPRMs for PCT?

[ionian]

19-nors are more suppressive than test/test derivatives and DHT/DHT derivatives because 19-nors bind to the progesterone receptors. In this case, would using a progesterone receptor antagonist or selective progesterone receptor modulator help to aid recovery after 19-nor cycles?

 

[Swifto]

No.

Blocking the progesterone receptor when hypogondal will not raise endogenous testosterone levels to a noticeable degree, if at all.

SERMS raise endogenous testosterone by blocking the estrogen receptors in the hypothalamus, or manipulating the bodies negative feedback loop. AI's work by lowering estrogen, fooling the body into increasing testosterone output, or changing the T:E ratio.

When you are in PCT, 99% of the time the steroid metabolites have left your body, or are no longer active and causing testosterone inhibition, so although using a PgR blocker might sound a good idea, put into practice, it wont do much.

 

[ionian]

No.

Blocking the progesterone receptor when hypogondal will not raise endogenous testosterone levels to a noticeable degree, if at all.

SERMS raise endogenous testosterone by blocking the estrogen receptors in the hypothalamus, or manipulating the bodies negative feedback loop. AI's work by lowering estrogen, fooling the body into increasing testosterone output, or changing the T:E ratio.

When you are in PCT, 99% of the time the steroid metabolites have left your body, or are no longer active and causing testosterone inhibition, so although using a PgR blocker might sound a good idea, put into practice, it wont do much.

Thanks Swifto. Would blocking the progesterone during, instead of after, the cycle reduce/eliminate the suppression caused by 19-nors?

 

[TrinityD]

Good answer..

No using prami during your cycle wont do anything to help your recovery from nandrolone (example).

 

[Swifto]

Thanks Swifto. Would blocking the progesterone during, instead of after, the cycle reduce/eliminate the suppression caused by 19-nors?

Nope.

You cant limit the amount of testosterone inhibition with SERMs, AI's or anything else IMO. steroid cycles cause too much androgen activity and you cannot fool the bodies negative feedback loop.

The only way you can limit testosterone suppression is to treat the testes directly with HCG when on an anabolic steroid cycle.

Forget trying to limit testosterone suppression with drugs on cycle, it wont work. You have HCG and HMG to keep the testes functioning and thats about it.