Trevogrumab in Enhanced Bodybuilders — Worth the Risk?

[bbxtreme]

Everyone saw what happened with GLPs.

They were made for diabetes, then obesity… and now they’re everywhere in bodybuilding. Especially Reta. That escalated fast.

Now trevogrumab is just starting to circulate. I know we had a thread on here last year discussing them being a few years away and now they’re here.

So it’s not whether guys will try it — they will. The real question is whether it takes off like GLPs did.

GLPs made sense for competitors. Appetite control. Staying tighter in prep. Managing insulin sensitivity. There was a clear reason to use them.

Trevogrumab was studied for muscle wasting and dystrophy. That’s not enhanced bodybuilders already running high-dose gear, GH, insulin, and pushing serious training volume.

If myostatin was the big limiter, the guys running grams would already look drastically different.

From what we’ve seen with this class, increases in lean mass don’t always equal strength or actual performance. And stacking a monoclonal antibody on top of heavy androgens and high mechanical load is unknown territory long-term.

Personally, if I want more size, I’d rather adjust food, training, recovery, or even gear before jumping to a biologic designed for disease states.

That’s just my perspective.

Curious to hear from anyone actually running it or planning to. Do you think this becomes the next GLP wave, or is this just early hype?

 

[luki7788]

Yes, I'm sure it will be another game changer - people will use everything and in the age of IA we won't wait years for it, only months at most - of course it will take years to pass all the tests necessary for FDA approval (and it's more likely it won't pass the tests lol) but I feel it will be available on the black market very soon

 

[bbxtreme]

Yes, I'm sure it will be another game changer - people will use everything and in the age of IA we won't wait years for it, only months at most - of course it will take years to pass all the tests necessary for FDA approval (and it's more likely it won't pass the tests lol) but I feel it will be available on the black market very soon

It’s already available here in the US through peptide companies. Much quicker than I thought it would be.

 

[luki7788]

It is definitely more difficult to produce than AAS or peptides, so honestly, I would have a hard time trusting UGL sources, especially at such an early stage of these compounds' existence.

 

[Duke309]

It’s already available here in the US through peptide companies. Much quicker than I thought it would be.

How much of this stuff being sold is real though?

 

[bbxtreme]

How much of this stuff being sold is real though?

Not sure. The supplier who I know that has it just got it in and has always been solid. But in today’s climate… who knows as Luki said above. There’s a reason I dropped my sponsor. Trust but verify. Which I’m not sure we can do given how new it is.

 

[specter]

Im still excitedly waiting for when all these "game changers" are gonna spill over into the results we see at bodybuilding shows... seems to me that so far not much have changed in the last 20 years, more drugs yes, better results ?

 

[luki7788]

Im still excitedly waiting for when all these "game changers" are gonna spill over into the results we see at bodybuilding shows... seems to me that so far not much have changed in the last 20 years, more drugs yes, better results ?

When I wrote “game changer”, I did not really mean the effects.
I meant more the popularity in the bodybuilding world. And because of that, also the popularity on the black market and among underground lab producers.

Hehe, lol.

 

[bbxtreme]

Im still excitedly waiting for when all these "game changers" are gonna spill over into the results we see at bodybuilding shows... seems to me that so far not much have changed in the last 20 years, more drugs yes, better results ?

Agreed. I can’t even say that GLP’s have translated to better physiques on stage.

But if myostatin inhibitors were the holy grail we would have a different level of bodybuilders on stage already… and we don’t.

 

[madg]

Not sure. The supplier who I know that has it just got it in and has always been solid. But in today’s climate… who knows as Luki said above. There’s a reason I dropped my sponsor. Trust but verify. Which I’m not sure we can do given how new it is.

I always knew you are bodybuilder in heart and a real man

My respect gone up for you 1000% more after your action

Hats off brother stay real we not many of us left

 

[Splitzz]

Know someone who’s ran it and I’ll be trying it out when I can afford it. Some crazy gains have been made with that product so far that I’ve heard of.

 

[bbxtreme]

Know someone who’s ran it and I’ll be trying it out when I can afford it. Some crazy gains have been made with that product so far that I’ve heard of.

Any idea how much they were using if you can share? I know currently it’s near $200 per 1mg vial so isn’t cheap.

I’m not in a phase to try it personally, but am certainly following anyone who does objectively.

 

[Splitzz]

Any idea how much they were using if you can share? I know currently it’s near $200 per 1mg vial so isn’t cheap.

I’m not in a phase to try it personally, but am certainly following anyone who does objectively.

10mg a week. It’s about 7k for a descent cycle of it right now

 

[Sectør]

10mg a week. It’s about 7k for a descent cycle of it right now

I’m sure the price will come down soon-ish (within the next year or two if or when Chinese production ramps)

Seems like the company regeneron is already working on and it’s in phase 2 clinical trials

Meaning the patent/formula is readily available, meaning the Chinese chem companies will likely rip it off, and make their own and start selling it like they did with Reta.

Will it work? No idea, but I’m sure there will be plenty of people willing to guinea pig it once the price gets a little more reasonable. $7k for a cycle of something might that might not even work? Better off investing in increlex at that point

 

[mexbeast]

I'm getting older, 51 so anything that decreases muscle and bone loss is appealing to me, but i like waiting a while before i try new things, i really don't like being a Guinea pig anymore!

 

[dantes]

Agreed. I can’t even say that GLP’s have translated to better physiques on stage.

But if myostatin inhibitors were the holy grail we would have a different level of bodybuilders on stage already… and we don’t.

It’s funny how hyped GLPs still are. In reality if you can get just as shredded without it you would have better results as you wouldn’t have the reduced gut motility and reduced glycogen uptake.

I think the only new drugs which brought something new to the market are the healing peptides but these are not necessarily advancing bodybuilding

 

[qbkilla]

It’s funny how hyped GLPs still are. In reality if you can get just as shredded without it you would have better results as you wouldn’t have the reduced gut motility and reduced glycogen uptake.

I think the only new drugs which brought something new to the market are the healing peptides but these are not necessarily advancing bodybuilding

Can't disagree. People have been getting shredded for quite some time without them. No one wants to hear move more eat less....but science is science lol

 

[specter]

When I wrote “game changer”, I did not really mean the effects.
I meant more the popularity in the bodybuilding world. And because of that, also the popularity on the black market and among underground lab producers.

Hehe, lol.

No worries my man, i knew what you meant.

 

[specter]

Know someone who’s ran it and I’ll be trying it out when I can afford it. Some crazy gains have been made with that product so far that I’ve heard of.

We heard the same with Increlex it was the "holy grail" bla bla bla.. until some guy steps on stage at 400lbs ripped i aint buyin the sales pitch.. being hyper bole here offcourse.

 

[qbkilla]

We heard the same with Increlex it was the "holy grail" bla bla bla.. until some guy steps on stage at 400lbs ripped i aint buyin the sales pitch.. being hyper bole here offcourse.

You never hear about it anymore. Why didn't it become a thing? I assume cost? I feel like I also read reports on boards that guys said when they came off, the look faded that they had on it. I remember back around 2004 lr igf came out and was all hyped too