Anyone here of this before? This came in an email from one of our sponsors. Lookd pretty interesting!
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We are excited to be able to bring to the market a new research peptide that that stimulates the hypothalamus to secrete GnRH into the hypophysial portal bloodstream which results in the activation of proteins involved in the synthesis and secretion of the gonadotropins LH and FSH.
In males LH (Luteinizing hormone) stimulates Leydig cell production of testosterone.
In males FSH (Follicle-stimulating hormone) stimulates the maturation of seminiferous tubules and spermatogenesis.
We think this is revolutionary. Why?
In the past the options may have been clomiphene and tamoxifen. There is a significant amount of research today that illuminates the following side-effects of those SERMs: low libido, erectile dysfunction, emotional instability, ocular toxicity and hepatocellular carcinoma- just to name a few.
The other option may have been HCG. A fine option. But one that requires a very specific daily protocol, and a protocol that if not followed in a disciplined manner, may damage the endocrine system further.
Besides, GnRH is a naturally occurring neurohormone. The body does not produce clomiphene citrate, tamoxifen or *HCG naturally (*unless you are pregnant).
The problem with GnRH in the past has been that in order for it to effectively exert its actions upon the pituitary gland, several pulses over several days would need to be stimulated. These required an infusion pump in many cases. Or if too much GnRH was given it would eventually decrease pituitary secretion of gonadotropins.
After several agonists and analogues of GnRH later- we now have Triptorelin.
The research peptide Triptorelin is a decapeptide that is modeled after the hypothalamic neurohormone GnRH, that interacts with the gonadotropin-releasing hormone receptor to elicit its biologic response, the release of the pituitary hormones FSH and LH.
We have found the exact amount of Triptorelin (100mcg) to administer to stimulate the release of LH and FSH and at the same time not overexert its effects on the pituitary gland.
That is one-singular injection of Triptorelin (100mcg) to completely restore endocrine function! One and done!!!
The protocol is found in the Triptorelin test that is used clinically to diagnose disease of the endocrine system. Below is the medical abstract that illustrates the success of this peptide in restoring endocrine function:
Anabolic steroids purchased on the Internet as a cause of prolonged hypogonadotropic hypogonadism
Objective
To report a case of hypogonadotropic hypogonadism due to the chronic abuse of anabolic steroids purchased over the Internet.
Design
Case report.
Setting
Endocrinology unit of the University of Brescia.
Patient(s)
A 34-year-old man.
Intervention(s)
A single dose (100 μg) of triptorelin (triptorelin test).
Main Outcome Measure(s)
Clinical symptoms, androgen normalization, levels of serum testosterone, follicle-stimulating hormone, and luteinizing hormone.
Result(s)
Within 1 month, the patient's serum testosterone was in the normal range, and he reported a return to normal energy and libido.
Case report
A 34-year-old man presented to our department in September 2008 for loss of libido and energy and for mild depression. He was a computer programmer and a nonprofessional bodybuilder with an unremarkable personal medical history. He admitted to having used doping drugs since he was 21 years old. More specifically, he would perform cycles of intramuscular injections of nandrolone (25 mg) and stanazol (25 mg) daily for 8 weeks, followed by mesterolone (50 mg/day) for 15 days. Then he would then take clomiphene citrate (50 mg/day) for 1 week, followed by an injection of human chorionic gonadotropin (2,000 IU) three times in 1 week. He had repeated these cycles from 1995 to 2005. From 2005 to August 2008, to his nandrolone and stanazol cycle he added an intramuscular injection of boldenone (50 mg) daily for 3 weeks. He said he had bought all the drugs on the Internet.
The patient was 175 cm tall and 80 kg, and he appeared very muscular and toned. His blood pressure and pulse rate were normal. Examination of his heart, lungs, and abdomen were likewise unremarkable. The physical examination showed normal secondary sexual characteristics, but the genital examination revealed bilateral testicular atrophy (volume 2.9 mL and weak consistence). Despite his testicular atrophy, the semen analysis revealed a normal count (79 × x106spermatozoa/mlmL) and mild morphology derangements (between 46% and 58%). The blood count and chemistry were normal, but his level of creatine kinase was 454 IU/L (normal range: 20--170 IU/L), alanine aminotransferase 61 IU/L (normal range: 5--50 IU/L), and aspartate aminotransferase 23 IU/L (normal range: 5--50 IU/L).
In February 2009, the patient continued to report loss of libido and great tiredness. A second physical examination was performed. His levels of alanine transferase and creatine kinase were all within the normal range, but the endocrinologic investigations were still abnormal with the exception of sex hormone-binding globulin level. *The patients testosterone measured 0.3 ng/mL - normal range is between 2.0 ng/mL and 12 ng/ML. Because the situation had persisted for months after ASS withdrawal, we administered a single dose (100 μg) of triptorelin (triptorelin test), which showed a normal response (Fig. 1). Ten days after the triptorelin test, the patient reported a great amelioration of energy, and his serum testosterone was 7.0 ng/mL. One month later, his serum testosterone was within the normal range, and he reported a return to normal libido and energy.
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