Very high calcium score. Looks like my PED use days are over...

[j2048b]

I got it approved… i went thru a telehealth and the pharmacy reached out thru my insurance and told them i couldnt take statins and had high cholesterol for the past 20 yrs…

All u got to do is tell them u had blood clots while on statins and ur a non responder… ull get approved for repatha tbh

 

[beastmode121]

Wait, you’re on xeralto and on gear? U played yourself .. and why are you on a blood thinner?

 

[j2048b]

Wait, you’re on xeralto and on gear? U played yourself .. and why are you on a blood thinner?

If ur referring to me, no. I got blood clots when i started statins and they took me off right away

 

[Alpha246]

Look into vitamin k mk7. It shuttles calcium where it's supposed to go and not to the arteries.

 

[gungalunga]

Wait, you’re on xeralto and on gear? U played yourself .. and why are you on a blood thinner?

If you are referring to me the Xarelto is because I had a blood clot in my liver a couple years ago. It has been prescribed to me by a hematologist since then.

 

[alfresco]

There are many studies showing those with low cholesterol have shorter life spans then those over 200(which is recommended). This study with 12.8 million people show levels of 215-220 live the longest on the average. Most studies in the US just look at the heart and lower heart attack risks. But cholesterol is used in many functions in the body.

Total cholesterol and all-cause mortality by sex and age: a prospective cohort study among 12.8 million adults - PubMed

It is unclear whether associations between total cholesterol (TC) levels and all-cause mortality and the optimal TC ranges for lowest mortality vary by sex and age. 12,815,006 Korean adults underwent routine health examinations during 2001-2004, and were followed until 2013. During follow-up...

pubmed.ncbi.nlm.nih.gov

Good info. Yes, many uses.

The first place cholesterol goes in your body is the brain.

 

[buck]

Good info. Yes, many uses.

The first place cholesterol goes in your body is the brain.

I agree in sentiment but my understanding is the brain produces it's own cholesterol as the molecule is to big to cross the blood brain barrier though some metabolites can. But at least some statins can get in and slow/shut production down. With dementia and Alzheimer's on they rise just seems like something for people to consider when masking the best choice for themselves. When i asked a couple cardiologists about that they said iris something for me to consider. So i asked them shouldn't they also be considering the long term ramification to the body as they are the ones prescribing the drug. Got no response from either. They seem to not look farther then what is said to be good for the heart.

 

[alfresco]

I agree in sentiment but my understanding is the brain produces it's own cholesterol as the molecule is to big to cross the blood brain barrier though some metabolites can. But at least some statins can get in and slow/shut production down. With dementia and Alzheimer's on they rise just seems like something for people to consider when masking the best choice for themselves. When i asked a couple cardiologists about that they said iris something for me to consider. So i asked them shouldn't they also be considering the long term ramification to the body as they are the ones prescribing the drug. Got no response from either. They seem to not look farther then what is said to be good for the heart.

True story.

 

[Joltan]

I see you included high dose vitamin D in your supplements. Have you ever had your labs pulled to find out where your actual vitamin D level is at? If you take too much vitamin d it piles up calcium deposits fast…

I take 5000iu daily and it puts me right into the 75th percentile range. But it can vary significantly per individual, and even race. If you spend a lot of time in the sun you could already have pretty high levels to begin with. Worse implications for smokers or anything inflammatory like that. There are quite a few studies, but will post a couple here for reference.

Vitamin D in Vascular Calcification: A Double-Edged Sword? - PMC

Vascular calcification (VC) as a manifestation of perturbed mineral balance, is associated with aging, diabetes and kidney dysfunction, as well as poorer patient outcomes. Due to the current limited understanding of the pathophysiology of vascular ...

pmc.ncbi.nlm.nih.gov

This article provides a comprehensive review of the biphasic role of vitamin D in vascular calcification, highlighting evidence from multiple animal models (mice, rats, goats, and pigs) where high-dose vitamin D administration led to significant arterial calcification. For example, it notes that in rats, sublethal doses (7.5 mg/kg) of vitamin D plus nicotine caused a 10–40 fold increase in aortic calcium content, resulting in calcification and destruction of medial elastic fibers, leading to arterial stiffness. In mice, single doses of 500,000 IU/kg/day induced severe aortic medial calcification within 7 days. The study also discusses mechanisms, such as elevated serum calcium and cholesterol levels, and the role of vitamin D receptor (VDR) signaling in promoting calcification when excessively stimulated. This source is robust due to its detailed analysis of experimental data and its discussion of both hypervitaminosis D and deficiency in the context of vascular health.



"Effect of Vitamin D Supplementation on Aortic Stiffness and Arterial Hemodynamics in People With Type 2 Diabetes and Hypertension" by Raed A et al., published in Journal of Clinical Endocrinology & Metabolism (2017).

This randomized, double-blind, placebo-controlled trial investigated high-dose vitamin D supplementation (100,000 IU monthly, equivalent to ~3,333 IU/day) in 130 patients with type 2 diabetes and hypertension over 12 months. The study found that high-dose vitamin D significantly increased aortic stiffness (measured by pulse wave velocity) and was associated with a trend toward increased vascular calcification markers, such as fetuin-A and matrix metalloproteinase activity. While the study did not directly measure arterial calcium content, the observed increase in aortic stiffness suggests a potential link to vascular calcification, consistent with preclinical data. The authors caution that excessive vitamin D may have adverse cardiovascular effects in high-risk populations.

This study is notable for its rigorous design and focus on a relevant human population, though direct evidence of calcification (e.g., via imaging) was not the primary endpoint.

 

[Joltan]

AI overusage can leach calcium from the bones and cause elevated blood calcium levels. I get this with armidex and letro.

This. Combined with crashed estrogen and you have a perfect recipe for cardiovascular disease.

I personally would never touch an AI after learning how bad they can be. Aromasin if anything… but Proviron, primo and masteron are the tried and true methods of the guys from the 70’s. There are other natural methods that work too… I think there are even ways to increase liver estrogen metabolism to get more out of your system quicker bc it can pile up with a bogged down liver (NAC, Calcium D Glucarate, Milk Thistle, kratom).

 

[KingOfSushi]

Look into vitamin k mk7. It shuttles calcium where it's supposed to go and not to the arteries.

I see you included high dose vitamin D in your supplements. Have you ever had your labs pulled to find out where your actual vitamin D level is at? If you take too much vitamin d it piles up calcium deposits fast…

I take 5000iu daily and it puts me right into the 75th percentile range. But it can vary significantly per individual, and even race. If you spend a lot of time in the sun you could already have pretty high levels to begin with. Worse implications for smokers or anything inflammatory like that. There are quite a few studies, but will post a couple here for reference.

Vitamin D in Vascular Calcification: A Double-Edged Sword? - PMC

Vascular calcification (VC) as a manifestation of perturbed mineral balance, is associated with aging, diabetes and kidney dysfunction, as well as poorer patient outcomes. Due to the current limited understanding of the pathophysiology of vascular ...

pmc.ncbi.nlm.nih.gov

This article provides a comprehensive review of the biphasic role of vitamin D in vascular calcification, highlighting evidence from multiple animal models (mice, rats, goats, and pigs) where high-dose vitamin D administration led to significant arterial calcification. For example, it notes that in rats, sublethal doses (7.5 mg/kg) of vitamin D plus nicotine caused a 10–40 fold increase in aortic calcium content, resulting in calcification and destruction of medial elastic fibers, leading to arterial stiffness. In mice, single doses of 500,000 IU/kg/day induced severe aortic medial calcification within 7 days. The study also discusses mechanisms, such as elevated serum calcium and cholesterol levels, and the role of vitamin D receptor (VDR) signaling in promoting calcification when excessively stimulated. This source is robust due to its detailed analysis of experimental data and its discussion of both hypervitaminosis D and deficiency in the context of vascular health.



"Effect of Vitamin D Supplementation on Aortic Stiffness and Arterial Hemodynamics in People With Type 2 Diabetes and Hypertension" by Raed A et al., published in Journal of Clinical Endocrinology & Metabolism (2017).

This randomized, double-blind, placebo-controlled trial investigated high-dose vitamin D supplementation (100,000 IU monthly, equivalent to ~3,333 IU/day) in 130 patients with type 2 diabetes and hypertension over 12 months. The study found that high-dose vitamin D significantly increased aortic stiffness (measured by pulse wave velocity) and was associated with a trend toward increased vascular calcification markers, such as fetuin-A and matrix metalloproteinase activity. While the study did not directly measure arterial calcium content, the observed increase in aortic stiffness suggests a potential link to vascular calcification, consistent with preclinical data. The authors caution that excessive vitamin D may have adverse cardiovascular effects in high-risk populations.

This study is notable for its rigorous design and focus on a relevant human population, though direct evidence of calcification (e.g., via imaging) was not the primary endpoint.

I believe earlier in the thread OP said he is taking a high dose of vit k already

 

[gungalunga]

I believe earlier in the thread OP said he is taking a high dose of vit k already

Yes. I've been taking D3 and K2 for quite a while now. By the studies Joltan posted, I may not have been doing myself any favors. I would suggest when you get your bloodwork done, get your vit D levels checked.

 

[Swifto]

I see you included high dose vitamin D in your supplements. Have you ever had your labs pulled to find out where your actual vitamin D level is at? If you take too much vitamin d it piles up calcium deposits fast…

I take 5000iu daily and it puts me right into the 75th percentile range. But it can vary significantly per individual, and even race. If you spend a lot of time in the sun you could already have pretty high levels to begin with. Worse implications for smokers or anything inflammatory like that. There are quite a few studies, but will post a couple here for reference.

Vitamin D in Vascular Calcification: A Double-Edged Sword? - PMC

Vascular calcification (VC) as a manifestation of perturbed mineral balance, is associated with aging, diabetes and kidney dysfunction, as well as poorer patient outcomes. Due to the current limited understanding of the pathophysiology of vascular ...

pmc.ncbi.nlm.nih.gov

This article provides a comprehensive review of the biphasic role of vitamin D in vascular calcification, highlighting evidence from multiple animal models (mice, rats, goats, and pigs) where high-dose vitamin D administration led to significant arterial calcification. For example, it notes that in rats, sublethal doses (7.5 mg/kg) of vitamin D plus nicotine caused a 10–40 fold increase in aortic calcium content, resulting in calcification and destruction of medial elastic fibers, leading to arterial stiffness. In mice, single doses of 500,000 IU/kg/day induced severe aortic medial calcification within 7 days. The study also discusses mechanisms, such as elevated serum calcium and cholesterol levels, and the role of vitamin D receptor (VDR) signaling in promoting calcification when excessively stimulated. This source is robust due to its detailed analysis of experimental data and its discussion of both hypervitaminosis D and deficiency in the context of vascular health.



"Effect of Vitamin D Supplementation on Aortic Stiffness and Arterial Hemodynamics in People With Type 2 Diabetes and Hypertension" by Raed A et al., published in Journal of Clinical Endocrinology & Metabolism (2017).

This randomized, double-blind, placebo-controlled trial investigated high-dose vitamin D supplementation (100,000 IU monthly, equivalent to ~3,333 IU/day) in 130 patients with type 2 diabetes and hypertension over 12 months. The study found that high-dose vitamin D significantly increased aortic stiffness (measured by pulse wave velocity) and was associated with a trend toward increased vascular calcification markers, such as fetuin-A and matrix metalloproteinase activity. While the study did not directly measure arterial calcium content, the observed increase in aortic stiffness suggests a potential link to vascular calcification, consistent with preclinical data. The authors caution that excessive vitamin D may have adverse cardiovascular effects in high-risk populations.

This study is notable for its rigorous design and focus on a relevant human population, though direct evidence of calcification (e.g., via imaging) was not the primary endpoint.

"...Focus on a relevant human population"?

Your first study is on rodents and animal models and second is on people with type 2 diabetes/hypertension and only 130 subjects.

 

[IFBBProDomCardone]

Not sure if its been mentioned here, have you looked into or heard about "koncentrated K"? A client recently told me about it, the man who released it supposdly reversed his plaque build up with it. I also saw an interview of chase irons telling vigorous steve thats how he reversed his within a few months.

 

[KingOfSushi]

Not sure if its been mentioned here, have you looked into or heard about "koncentrated K"? A client recently told me about it, the man who released it supposdly reversed his plaque build up with it. I also saw an interview of chase irons telling vigorous steve thats how he reversed his within a few months.

Yep, chase did 2 caps a day and brought his calcium score back to zero.

I take one cap a day year round of it.

 

[NEMSZ]

Not sure if its been mentioned here, have you looked into or heard about "koncentrated K"? A client recently told me about it, the man who released it supposdly reversed his plaque build up with it. I also saw an interview of chase irons telling vigorous steve thats how he reversed his within a few months.

I’ve been using koncentrated K for 2 years since I saw that, my calcium score has remained basically the same..

I’ve seen some people have been able to reverse it with different protocols, but it doesn’t seem to be a universal thing..

There’s no harm in trying but it seems to be the people who can actually reverse their calcium score are far and few between..

 

[KingOfSushi]

I’ve been using koncentrated K for 2 years since I saw that, my calcium score has remained basically the same..

I’ve seen some people have been able to reverse it with different protocols, but it doesn’t seem to be a universal thing..

There’s no harm in trying but it seems to be the people who can actually reverse their calcium score are far and few between..

What’s your score?

 

[NEMSZ]

What’s your score?

On a CT Calcium score test it was 15-17 both times I did it, on a CT Angiogram it was 25, which I take to be more accurate..

 

[Zamun]

This. Combined with crashed estrogen and you have a perfect recipe for cardiovascular disease.

I personally would never touch an AI after learning how bad they can be. Aromasin if anything… but Proviron, primo and masteron are the tried and true methods of the guys from the 70’s. There are other natural methods that work too… I think there are even ways to increase liver estrogen metabolism to get more out of your system quicker bc it can pile up with a bogged down liver (NAC, Calcium D Glucarate, Milk Thistle, kratom).

I wouldn’t say AI’s are bad.

The effects of crashed e2 are bad but not AI’s inherently. Primo hits my bloodwork worse at a female dose (200mg) than a half a tab of aromasin would.

 

[Swifto]

Yep, chase did 2 caps a day and brought his calcium score back to zero.

I take one cap a day year round of it.

He didn't only take Koncentrated K.