I stopped taking melatonin recently due to some claims that long term use is linked to higher heart failure risk.
Worth a read...
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Long-term use of melatonin supplements linked to higher risk of heart failure and death
Long-term use of melatonin supplements, often used to promote sleep and address insomnia, was associated with a higher risk of heart failure diagnosis, heart failure hospitalization and death from any cause in chronic insomnia, according to a preliminary study to be presented at the American...www.news-medical.net
The researchers also lacked information on the severity of insomnia and the presence of other psychiatric disorders.
"Worse insomnia, depression/anxiety or the use of other sleep-enhancing medicines might be linked to both melatonin use and heart risk," Nnadi said. "Also, while the association we found raises safety concerns about the widely used supplement, our study cannot prove a direct cause-and-effect relationship. This means more research is needed to test melatonin's safety for the heart.
I'm sure that's different for everybody. Just ride that train when you feel it.Melatonin usually like 40 mins or so before bed. Not sure if that’s the best timing, just kind of winging it
25 years of consecutively taking melatonin. No heart failure here.
Look at the populations of individuals in that useless piece of paper and see what other comorbidities may be responsible.
Do you have any thoughts on melatonin dosages or people building a tolerance over time? I've upped my dosages, now at 40, still waking up at 4 am even with 2x thc cbn gummies, stack used to work like a charm. Will be adding magnesium.25 years of consecutively taking melatonin. No heart failure here.
Look at the population base of individuals in that useless piece of paper and see what other comorbidities may be responsible.
How do you get over the next day grogginess from the high doses you take? I tried to ramp up past 10mg and it just ended up making me so groggy the next day.25 years of consecutively taking melatonin. No heart failure here.
Look at the population base of individuals in that useless piece of paper and see what other comorbidities may be responsible.
Did you just start waking up at 4am after becoming used to supplementing melatonin, or did you start taking melatonin after this issue appeared?Do you have any thoughts on melatonin dosages or people building a tolerance over time? I've upped my dosages, now at 40, still waking up at 4 am even with 2x thc cbn gummies, stack used to work like a charm. Will be adding magnesium.
I've been using 2 thc/cbn gummies +30mg melatonin for a while it worked well. But for about 3 weeks I've been wakeup at 4 to piss and can't go back to sleep. So bumped up to 40mg no help. Imma add magnesium i read melatonin is more for falling asleep where mag is more for staying asleep.Did you just start waking up at 4am after becoming used to supplementing melatonin, or did you start taking melatonin after this issue appeared?
I ask because I started taking melatonin, up to 70mg nightly and it has been amazing, but after running tren at only 20 daily for 3 weeks recently, my sleep has been destroyed and I constantly wake up at 3am and am unable to go back to sleep. Isn’t as bad as it sounds as I wake up at 4-430 intentionally every morning anyways, but still.
I’m wondering if the short half life of melatonin is perhaps making early waking more likely. I’m debating trying a time release melatonin in combo with short acting.
I really don’t want to give up melatonin as it helps me fall asleep so easily, gives vivid dreams, and is basically the strongest anti oxidant around.
Same.Yeah magnesium has been a massive help for sleep (the glycinate version)
I’d highly recommend it if you haven’t used it . It’s been great for me
I recently pulled ALL of my supplements. I learned a few things:
1. I didn’t need 90% of the crap I was taking.
2. My digestion and GI has never been better.
The amount of stomach acid and stress all the supplement capsule breakdown was causing was just eye opening.
I then ran bloodwork to see what I actually needed.
Magnesium Glycinate- 400-600mg daily
Vitamin D3- 5000iu
CoQ10- 200mg daily (the OG mitochondrial support)
That’s it. More is not always better in this sport. And I say this as someone who made a thread on this and was taking endless things.
I am sorry but this article was thoroughly debunked all over social media for a week straight. Don’t fall for flawed studies.I stopped taking melatonin recently due to some claims that long term use is linked to higher heart failure risk.
Worth a read...
![]()
Long-term use of melatonin supplements linked to higher risk of heart failure and death
Long-term use of melatonin supplements, often used to promote sleep and address insomnia, was associated with a higher risk of heart failure diagnosis, heart failure hospitalization and death from any cause in chronic insomnia, according to a preliminary study to be presented at the American...www.news-medical.net
Yes GlyNAC works wonders and people with impaired glutathione (older or people who aren’t healthy) at very high doses but it didn’t show many benefits in men in their 20sI appreciate the input
Never knew that NAC and glycine would be synergistic. I’ll grab some more glycine tomorrow. I’ve used it before for sleep, and I think it was good, but there was too many variables to measure. I’ll definitely give it another try if you’re mentioning it. Haven’t heard of apigenin before though, I’ll definitely need to research that a bit.
Melatonin usually like 40 mins or so before bed. Not sure if that’s the best timing, just kind of winging it
Never really measured the prebiotics in food if I’m being honest. I feel like I get a decent amount, but whatever I lack there I think the supplements over account for. These are the ones I use. They have some overlap in function, so maybe overkill, but it’s worked well for digestion for me.
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The peptide version of ALCAR does interest me. Heard it’s very impressive for endurance and has some good fat loss benefits. I guess if the oral version has good bioavailability that might be a way easier alternative
If it was warranted based on my bloodwork I would take it. Same with Vitamin K, etc.Wow. Here I am thinking I'll die of a stroke if I forget to take my nattokinase...
No fish oil? Or are you getting omega 3s primarily from food sources?I recently pulled ALL of my supplements. I learned a few things:
1. I didn’t need 90% of the crap I was taking.
2. My digestion and GI has never been better.
The amount of stomach acid and stress all the supplement capsule breakdown was causing was just eye opening.
I then ran bloodwork to see what I actually needed.
Magnesium Glycinate- 400-600mg daily
Vitamin D3- 5000iu
CoQ10- 200mg daily (the OG mitochondrial support)
That’s it. More is not always better in this sport. And I say this as someone who made a thread on this and was taking endless things.





































































