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When and how to use Telmisartan and Nebivolol?

pietruzzo

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May 25, 2026
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I'm genuinely not sure how I should use Telmisartan and Nebivolol, and I'd like some advice.

I upped my test weekly dosage to 350mg a month ago and added 25mg daily injectable YK-11, and sure enough my resting heart rate hovers around 105 to 115 from the evening until late at night. Furthermore, I know the actual solution is to lower test down to 200 and drop YK-11 entirely, but for the time being I need to figure out a way around it to keep my heart in check.

So my question is, when does it make sense to use either Telmisartan or Nebivolol, or should they be used together?

What would be the recommended dosage for either?

Thanks
 
My advice, get off anything that is making your heart beat that fast.
 
Drop down to Trt and see what your heart rate is. That’s very high, never experienced a resting heart rate increase of that magnitude from just test and yk-11
 
To be fair the resting heart rate is not always that high and usually around 75/90. I noticed it spikes to 105/115 in the evening after eating my biggest meal of the day, especially if I had an intense workout day.
 
75-90 is still on the higher side. Do you do a cardio? What’s your blood pressure at?
Yes I do cardio, 25 minutes treadmill fasted in the morning. I'm not gonna lie I've never measured my blood pressure before. Just ordered the machine on Amazon.
 
Telmisartan and Nebivolol are the 'Holy Grail' of longevity in this sport, but they aren't supplements you just throw in blindly. Telmisartan is an ARB that not only manages BP but also has interesting PPAR-gamma activity, helping with insulin sensitivity and left ventricular hypertrophy (LVH) prevention.

Nebivolol is unique because it’s a highly selective beta-1 blocker that also increases nitric oxide (NO) production, which is great for the 'pump' and protecting the endothelium.

My protocol for athletes: Start with 20-40mg Telmi and 2.5mg Nebivolol only if your morning fasted BP is consistently above 135/85. Don't wait until you're at 150/90 to act. Managing blood pressure from day one is the difference between a 10-year career and a 30-year career.
 
Yes I do cardio, 25 minutes treadmill fasted in the morning. I'm not gonna lie I've never measured my blood pressure before. Just ordered the machine on Amazon.
BP is dependant on numerous factors. Take your readings first thing in the AM. While still lying in bed and relaxed. Qualify this as your baseline.

You can implement additional testing before and after meals to see the change and also in the evening once your in bed relaxed.
 
BP is dependant on numerous factors. Take your readings first thing in the AM. While still lying in bed and relaxed. Qualify this as your baseline.

You can implement additional testing before and after meals to see the change and also in the evening once your in bed relaxed.
I had it 170 over 100 due a combination of factors, I got a major scare.

I was not sleeping well due to stress and anxiety at work and the YK-11 was amplifying 2 notches. It came down to 125/75 now.

I will be measuring it first thing in the morning and before bed going forward.
 

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