Its an interesting discussion here.
I think its safe to say the best way to dose it is fasted upon awaking before cardio. Thats Ultimately when it works the best
as for dosing yohimbine or alpha yohimbine between meals, it may work. That said, the studies on yohimbine show insulin neglects the effects of yohimbine .
Ill use it after I get my heart rate up and a couple exercises at the gym , when I feel blood sugar, insulin drops.
I do feel bcaa's effect yohimbine hcl, I use to not. I had fasted blood work , and took five grams bcaa's, and five grams bcaa's effect insulin quite a bit.