New study shows it may be possible to reverse aging with Growth Hormone and Metformin

[Joltan]

https://www.nature.com/articles/d41586-019-02638-w

 

[whacked]

Nice. Metformin’s been a pretty popular anti-aging supplement/medication for many many years amongst the life extension enthusiasts.

Wonder if berberine works exact same way/confers the same benefits?

 

[buck]

I see where 1 of the 2 anti-diabetic drugs they used was DHEA, along with HGH and Metformin. Hopefully it was the reporter who misidentified DHEA as a diabetes medication. If it was the researcher I would throw the study out for not knowing what he was talking about.

 

[aphextwin]

Good to see since I have been using Met religiously for the last 3 months, swear it keeps you even leaner while eating even more food. That being said, I have a good metabolism already. I love Met...I'll use low does MK instead of growth....I know, they aren't the same...I get it

 

[Stewie]

https://joshmitteldorf.scienceblog....reversal-results-is-it-hgh-or-something-else/

 

[Knight9]

Good to see since I have been using Met religiously for the last 3 months, swear it keeps you even leaner while eating even more food. That being said, I have a good metabolism already. I love Met...I'll use low does MK instead of growth....I know, they aren't the same...I get it

Did you get the time released version? How was the GI gas/shit issues if there were any?

 

[nothuman]

I am sure people will see this and get excited thinking they can use a bunch of HGH and get younger, but the reality is the dose used was probably a small replacement dose.

 

[Stewie]

I believe there's more highlighted belief in the individualized epigenetic methylation patterns.

 

[nothuman]

https://joshmitteldorf.scienceblog....reversal-results-is-it-hgh-or-something-else/

Wow according to this Mitteldorf article (I love his site btw), HGH was 0.015mg/KG, which is a high dose if my math is correct here. That's like 4.5iu in a 92.5kg individual I think? If that's the case, I would guest the rest of the stack mitigated the deleterious effects of that. But who knows

 

[T-800]

Now thats what i call beautiful. Life can begin.

 

[aphextwin]

Did you get the time released version? How was the GI gas/shit issues if there were any?

I've used both. I'm currently using the non time released with no GI issues. I had those issues for a couple of days, but than they went away. I really can't say enough about Metformin. I probably won't ever stop using it.

 

[aphextwin]

https://joshmitteldorf.scienceblog....reversal-results-is-it-hgh-or-something-else/

Good stuff, Stewie. I use everything on the list except. HGH and DHEA. I just can't remember to take it. I just don't see the value in using it. Maybe I should reconsider, but doubt it.

 

[nothuman]

Good stuff, Stewie. I use everything on the list except. HGH and DHEA. I just can't remember to take it. I just don't see the value in using it. Maybe I should reconsider, but doubt it.

I use 25mg DHEA. TRT tends to lower DHEA so I had it tested and it was at the low end of the normal range. 25mg put me at an optimal level. I can't say for certain it's useful but I like knowing my blood level of it is good.

 

[nihilixm]

Wow according to this Mitteldorf article (I love his site btw), HGH was 0.015mg/KG, which is a high dose if my math is correct here. That's like 4.5iu in a 92.5kg individual I think? If that's the case, I would guest the rest of the stack mitigated the deleterious effects of that. But who knows

Think the metformin mitigates insulin sensitivity issues and the vitamin d DHEA make the igf more effective.

 

[Joltan]

Wow according to this Mitteldorf article (I love his site btw), HGH was 0.015mg/KG, which is a high dose if my math is correct here. That's like 4.5iu in a 92.5kg individual I think? If that's the case, I would guest the rest of the stack mitigated the deleterious effects of that. But who knows

Wow, i was thinking it was 1.4 but that was in MG...