You don`t need to use HCG if you are on the Humanofort. It contains Activin and Inhibin.
Activin and inhibin were first identified as proteins of central importance to reproductive biology for their capacity to regulate pituitary follicle-stimulating hormone (FSH) secretion. Research spanning nearly three decades has revealed a highly complex relationship between these highly conserved proteins and their “siblings” in the transforming growth factor β superfamily. Activin actions are critical in many organ systems, and knowledge of how activin is produced and controlled is relevant to many aspects of human health and disease. Sertoli cell function is intimately related to activin and inhibin biology; these cells are targeted by pituitary gland-derived FSH to regulate their synthesis, and their levels are a key determinant of male fertility and physiology. Research has identified specific roles for locally produced activin and inhibin in testicular development and function. This chapter updates material in the previous edition of this book [1], focusing on activin and inhibin biology in the testis, to reflect the rapid growth in our understanding of these factors.