GHRP and pituitary gland

[tweezor]

So I'll been thinking about jumping back on the ghrp train, but I came up with a few thoughts that may hold me back, hopefully someone can help me out

So we can only release whatever we have in our pituitary, is there any studie about how much that is? because lets say i only have the ability to release 3 UI of hgh, then it wouldnt matter how much or how often i shoot ghrp?
Also is there a negative feedback ? if I release a lot right away, can it actually end up hurting in the long run because I release a lot in the start and then there is less for the remaining time? or does the body just adapt on the go?

 

[HimRoid]

From DATBTRUE I believe certain GHRP's like ghrp2, ghrp6, ipamorelin do not caused much receptor down regulation. With ghrp2, ghrp6 at a dose of 100mcg your pituitary gland should replenish fully within 3 hours. Hexarelin is supposed to cause greater receptor down regulation but even after 4 months at 200mcg twice a day serum HGH wax still up around 10.
It's hard to quantify GH in ius from GH peptides.

The negative feedback loop would be the release of somatostatin which can be reduced with somatostatin inhibitors like huperzine A, horny goat weed, melatonin, nicotine, etc.