Triptorelin

[PLer1290]

Anyone ever used it in PCT?

 

[renewlyf]

Peptides & Growth Factor Forum

There is threads and some info there regarding this. Sounds very promising.

 

[dece870717]

http://www.professionalmuscle.com/f...n-completely-restores-endocrine-function.html

http://www.professionalmuscle.com/forums/peptides-growth-factors/70954-triptorelin-gnrh-log.html

If you read through the first link their are currently 2 guys talking about their experience with it.

 

[PLer1290]

I'm surprised more people haven't tried it if it's so promising though. I'll definitely try it.

 

[TwisT]

Its great stuff, I know this will change PCT as we know it. And yeah, I've taken it. Shoot me any questions you have

-T

 

[10brandonr]

good marketing yes, promising no... lol

 

[-Z-]

good marketing yes, promising no... lol

Care to explain? I just wanna hear what you think.

 

[PLer1290]

Care to explain? I just wanna hear what you think.

Same here.

 

[erespam]

 òî æå âðåìÿ ìíå íðàâèòñÿ òà çàãðóæåííîñòü, êîòîðàÿ íà ìåíÿ ñåé÷àñ íàâàëèëàñü, ïîòîìó ÷òî îíà íå îñòàâëÿåò ìíå âðåìåíè íà áåçäåëüå è âñÿêèå òÿãîñòíûå ðàçäóìüÿ". Ê êîíöó äíÿ ÿ ñëåãêà çàïàíèêîâàëà. Àðòåðèîñêëåðîç Îáðàçîâàíèå áëÿøêè íà çèìíåé äèåòû äëÿ ïîõóäåíèÿ ñòåíêå. È ñëîâíî ýêñòðàêò ôåéåðâåðêà, ñêâîçü ñòàâøóþ ïðîçðà÷íîé êðûøó, âîðâàëèñü áåøåíûì õîðîâîäîì çâåçäû àíàíàñà ìèðà.... Âàø ìàëûø ìîæåò ñòàòü íåðâíûì è êàïðèçíûì, ïîñêîëüêó íå ñìîæåò ñïîêîéíî çàñíóòü. **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** ×òîáû ñëåäèòü çà èçìåíåíèåì ñâîåãî âåñà, âçâåøèâàòüñÿ íóæíî 1 ðàç â äåíü óòðîì ïîñëå òóàëåòà â íèæíåì áåëüå. Ëó÷øå ñ ïîíåäåëüíèêà íà÷íèòå áåãàòü ïî óòðàì (íó èëè õîäèòü â ñïîðòçàë), íå åñòü ìó÷íîå, ñëàäêîå, æàðåííîå ïîðåæå, áîëüøå ïèòü âîäû…È òîãäà ýòè ëè÷íèå êèëîãðàììû óéäóò â íóæíîå ðóñëî (ïîÿâèòñÿ óïðóãèé æèâîò, ÿãèäèöû è ò. Çàòåì âëèòü îñòàëüíîé áóëüîí. Âîïðîñ: Ìíå 14 ëåò, âåøó 43, ðîñò 159.  êà÷åñòâå æèäêîñòè ìîæíî èñïîëüçîâàòü ÿáëî÷íûé ñîê. **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** Êðîìå òîãî, íåëüçÿ èñïîëüçîâàòü íèçêîêà÷åñòâåííûé äåøåâûé óêñóñ, äëÿ ïðîèçâîäñòâà êîòîðîãî èñïîëüçóþòñÿ ñïîñîáû óñêîðåííîé ôåðìåíòàöèè. Ïðàâäà, ñòàðàëàñü ìíîãî çàíèìàòüñÿ ñïîðòîì, ÷òîáû è ìûøöû íå ïîòåðÿòü è ïîäòÿíóòü èõ. Ïðè ðîñòå 177 áûë âåñ 70,ñòàë 64 çà íåäåëþ. Âûïèòü ìîæíî ÷àé èëè êîôå, íî áåç äîáàâëåíèÿ ñàõàðà. À ìóæ ïèâî ïüåò!!!! **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** **broken link removed** È åùå ìîæíî ëè íà÷èíàòü òðåíèðîâêó â 4÷àñà? Ïèòü äî 2 ëèòðîâ çåëåíîãî ÷àÿ â ñóòêè, íåãàçèðîâàííóþ ìèíåðàëüíóþ âîäó. Çàòî ò¸ïëûå òåððàêîòîâûå, ïåðñèêîâî-ðîçîâûå îòòåíêè åäâà ëè îêàæóòñÿ óìåñòíû. Áûëè ïîïûòêè ñáðîñèòü âåñ è äàæå äâå óñïåøíûå, íî âåñ âîçâðàùàëñÿ è, êàê ïðàâèëî, ñ åùå áîëüøèì ïëþñîì. Æèð íå âûäåëÿåòñÿ â áîëüøèõ êîëè÷åñòâàõ íè êîæåé.

 

[ShomWoolley]

can prilosec cause yellow stool 42

fda prilosec Athens and **broken link removed** Recommend:
P.S. Sorry for choosing "http://www.professionalmuscle.com/forums/professional-muscle-forum/71465-triptorelin.html" to leave a message for men about
professionalmuscle - awesome forum! Thank you!

 

[j4ever]

Its great stuff, I know this will change PCT as we know it. And yeah, I've taken it. Shoot me any questions you have

-T

How long has it been since you taken it?

 

[TwisT]

How long has it been since you taken it?

About 30 days/ish. Pretty much this stuff hits your body exactly like HcG does, but to a larger extent, and not only stimulates LH, but also FSH which is key for our testicles.

After about 2 years of having very very small testicles, I finally have some size back and am sustaining it... I did a little nolva after the initial shot just to keep my pituitary producing on its own, and its worked amazing. I'm now completely off... and I have testicles

-T

 

[fubaseball]

About 30 days/ish. Pretty much this stuff hits your body exactly like HcG does, but to a larger extent, and not only stimulates LH, but also FSH which is key for our testicles.

After about 2 years of having very very small testicles, I finally have some size back and am sustaining it... I did a little nolva after the initial shot just to keep my pituitary producing on its own, and its worked amazing. I'm now completely off... and I have testicles

-T

What about strength/size retention? Mainly strength...

 

[10brandonr]

There's no reason to assume it would work. GnRH agonists are nothing new and they have no potential for the treatment of hypogonadism. No studies support that any mechanism of dosing (1 microinjection, or multiple injections over time) any GnRH agonist will cause a permanent improvement in individuals with true hypogonadism. So the whole 1 small injection was NOT based on any science just sort of pulled out of the wind. That's good marketing and I applaud the peptide companies and do encourage experimentation by all individuals. But until a truly hypogonadic male (not temporarily induced low T from cycling) with low testosterone uses tripto to restore T levels above baseline I won't buy it. How you "feel" is not a good indication of recovery and and even blood tests after a cycle is not a good indication of tripto-induced recovery as there is no known baseline, no control, and no determining how it would compare to a SERM PCT or no PCT at all. Even comparing former blood tests does not show good results as testosterone levels can fluctuate dramatically throughout the day. It could only be proven if in a truly documented individual with permanently low testosterone, LH, FSH etc... can miraculously recover from a simple tripto administration.

Otherwise I just believe it will cause a spike in LH and FSH, followed by minor desensitization that bring you slightly below baseline, then followed by a return to baseline. The only benefit I see it having over SERMs is that you can avoid the side effects of SERMs. But SERMs have the benefit of still causing a high pulsatile release of LH and FSH through some indirect mechanism at the HPTA that will not lead to any significant deregulation. GnRH still works the same whether a little or alot is used, so I see using as no different than say trying to use a single shot of HCg during PCT or something.

 

[10brandonr]

And lets take a look at the only study that's ever supported a one low-dose injection of tripto theory....

From the full study:
- A study of one man.... real reliable
- His cycle and PCT looks a bit strange... either the man's an idiot or poor documentation by the doctors.
- Before treatment he suffered only from mild testicular atrophy and semen analysis showed he had a normal count and had no spermatogenesis dysfunction. (79 × x106 spermatozoa/mlmL). His only problem was a lack of energy and libido...
- The study made no effort to explain how long he had been off his cycle, only reporting "for a couple months". and did not explain if he had been on or off cycle during either of the blood tests.
- LH and FSH were within normal range (albeit lower range) in the last blood test done before treatment.
- Report fails to show blood test results after treatment, only reporting that the patient felt better and that serum testosterone was 7.0 ng/ml after 10 days... and that's as far as they tested.
- My favorite is in the discussion... where they discuss nothing about the case report and instead focus on performance doping in ancient civilizations, consumption by students, the trade of AAS online, and the science behind clomid.
- All of his values were in the process of recoverying from Sept to February.

Doping involves the use of artificial means or substances with the specific aim of improving performance, despite well-known adverse effects on health (1). This practice has spread to the general population, in particular to young adults, along with the exaggerated ideals of body image portrayed by the mass media (2), (3) and (4). Over the last few years, Internet marketing may have played an important role in increasing consumption of anabolic drugs such as anabolic androgen steroids (AAS) and clomiphene citrate (5). We describe the case of a young male with prolonged hypogonadotropic hypogonadism due to ongoing consumption of various doping drugs purchased over the Internet, where they are readily available.
Case report
A 34-year-old man presented to our department in September 2008 for loss of libido and energy and for mild depression. He was a computer programmer and a nonprofessional bodybuilder with an unremarkable personal medical history. He admitted to having used doping drugs since he was 21 years old. More specifically, he would perform cycles of intramuscular injections of nandrolone (25 mg) and stanazol (25 mg) daily for 8 weeks, followed by mesterolone (50 mg/day) for 15 days. Then he would then take clomiphene citrate (50 mg/day) for 1 week, followed by an injection of human chorionic gonadotropin (2,000 IU) three times in 1 week. He had repeated these cycles from 1995 to 2005. From 2005 to August 2008, to his nandrolone and stanazol cycle he added an intramuscular injection of boldenone (50 mg) daily for 3 weeks. He said he had bought all the drugs on the Internet.
The patient was 175 cm tall and 80 kg, and he appeared very muscular and toned. His blood pressure and pulse rate were normal. Examination of his heart, lungs, and abdomen were likewise unremarkable. The physical examination showed normal secondary sexual characteristics, but the genital examination revealed bilateral testicular atrophy (volume 2.9 mL and weak consistence). Despite his testicular atrophy, the semen analysis revealed a normal count (79 × x106 spermatozoa/mlmL) and mild morphology derangements (between 46% and 58%). The blood count and chemistry were normal, but his level of creatine kinase was 454 IU/L (normal range: 20–170 IU/L), alanine aminotransferase 61 IU/L (normal range: 5–50 IU/L), and aspartate aminotransferase 23 IU/L (normal range: 5–50 IU/L). The endocrinologic investigations are reported in Table 1.
Table 1. Serum hormone profile in a man with hypogonadotropic hypogonadism due to the chronic abuse of anabolic steroids.
Hormone September 2008 February 2009 Normal range
FSH (mIU/mL) 1 2 1.5–13.0
LH (mIU/mL) <0.5 2 1–8
HGH (ng/mL) <0.1 <0.1 <0.4
IGF (ng/mL) 241 — 109–307
TSH (mIU/L) 1.249 1.345 0.270–4.200
FT4 (pg/mL) 7.9 — 7–18
DHEAS (pg/mL) 2.2 — 0.80–5.60
E2 (pg/mL) <10 — 11–45
T (ng/mL) 0.3 1.7 2.7–10
PRL (ng/mL) 14.7 13.5 3.0–23
SHBG (nmol/L) 8 21 13–71
Note: DHEAS = dehydroepiandrosterone sulfate; E2 = estradiol; FSH = follicle-stimulating hormone; fT4 = free thyroxine; HGH = human growth hormone; IGF = insulin-like growth factor; LH = luteinizing hormone; PRL = prolactin; SHBG = sex hormone-binding globulin; T = testosterone; TSH = thyroid-stimulating hormone.

In February 2009, the patient continued to report loss of libido and great tiredness. A second physical examination was performed. His levels of alanine transferase and creatine kinase were all within the normal range, but the endocrinologic investigations were still abnormal with the exception of sex hormone-binding globulin level (see Table 1). Because the situation had persisted for months after ASS withdrawal, we administered a single dose (100 μg) of triptorelin (triptorelin test), which showed a normal response (Fig. 1). Ten days after the triptorelin test, the patient reported a great amelioration of energy, and his serum testosterone was 7.0 ng/mL. One month later, his serum testosterone was within the normal range, and he reported a return to normal libido and energy.


Full-size image (15K)
High-quality image (81K)

Figure 1.
Triptorelin test showing a normal response.

Discussion
Despite the perception that doping is a modern phenomenon, there are many examples of substance use by ancient civilizations, including extracts derived from plants or animals. Historically, the use of drugs in sports can be traced back to 776 B.C. One of the earliest reports describes the use of a diet of dried figs to improve the performance of Charmis, the Spartan winner of the stadium race at the Olympic Games of 668 B.C. (6). Later, Roman gladiators also used unspecified stimulants to overcome fatigue and injury (7). Amphetamines, the first “effective” performance-enhancing drugs, crossed over into sports in the early 1950s. These drugs, nicknamed la bomba by Italian cyclists, minimize the uncomfortable sensations of fatigue during exercise (8). Since then, many other substances have been used to improve athletic performance.
Epidemiologic data on the use and abuse of doping drugs are notoriously difficult to obtain because the drugs are illegal. Nevertheless, the use of these substances appears to have become widespread, ranging from the domain of elite athletics to the general community in many countries (5), (9), (10), (11) and (12). The popularity of doping drugs seems to be due to the large diffusion of print media, sports and bodybuilding magazines, advertisements, and television (5). Our patient reported over a decade of chronic consumption of a cocktail of doping drugs, mainly androgens, which caused his prolonged hypogonadotropic hypogonadism; all were purchased on Internet sites.
The side effects of the use and abuse of high doses of anabolic steroids have been well documented. After the first report, a fatal heatstroke in a cyclist in 1967 after abuse of amphetamines (8), many other reports have described the side effects of doping drugs (13), (14), (15), (16), (17), (18) and (19). Because they derive from testosterone, anabolic steroids have pronounced effects on the male pituitary gonadal axis, affecting the regulation of production of serum luteinizing hormone (LH) and follicle-stimulating hormone and inducing a state of hypogonadotropic hypogonadism characterized by decreased serum endogenous testosterone production and impaired spermatogenesis, often reversible with withdrawal of the drugs (19). Another consequence of ASS abuse is the reduction of sex hormone-binding globulin, which will continue long after ASS withdrawal (20).
Our patient showed no spermatogenesis dysfunction, even though he had used anabolic steroids for over a decade. This could be explained by his periodic self-administered treatment with clomiphene citrate and human chorionic gonadotropin between the cycles of steroids. Clomiphene is a selective estrogen receptor modulator that blocks the feedback inhibition of estradiol at the level of the hypothalamus, thus increasing pituitary release of both LH and follicle-stimulating hormone (5) and (21). In addition, clomiphene decreases the conversion of androgen substrate to estrogen by aromatase inhibition (22). It is this ability to block estrogen that leads to its postcycle use by bodybuilders to reduce the development of gynecomastia after self-administration of androgen drugs. Clomiphene is extensively used in the induction of ovulation (23), but it has also been used to reverse hypogonadotropic hypogonadism in many conditions like falciform anemia, uremia, and alcohol abuse, and it stimulates gonadotropin secretion in patients with sulpiride-induced hyperprolactinemia and gonadotropin suppression (24).
Moreover, clomiphene and LH (LH–RH) have been successfully used to treat severe hypothalamic-pituitary dysfunction due to anabolic steroid abuse. Van Breda et al. (17) reported that supraphysiologic doses of LH-RH restored normal pituitary–testicular axis interplay, and Tan et al. (25) used prolonged clomiphene citrate treatment to cure symptomatic hypogonadism in bodybuilders. The cycles of pituitary stimuli with clomiphene and human chorionic gonadotropin could also explain why our patient did not exhibit the hypothalamic-pituitary dysfunction that had been clinically evident previously.
The most important information relevant to the present case, in our opinion, is the apparent ease with which one can purchase these substances on the Internet. Indeed, very recently, Melnik (5) condemned the “role of the World Wide Web” in illegal drug marketing, reporting more than 47,500 new steroid-related cases in 2006, for an increase of 400% since their debut in 2002 (26). Many online bodybuilding stores also give information on the use and combination of drugs, their dosages, and their side effects. We have personally purchased stanazol, nandrolone, and other doping drugs online, confirming how easy it is to obtain these drugs over the Internet. Even though it has been largely demonstrated that more than 50% of illicit androgens are made available to the fitness community by licensed health-care providers (5), in our opinion the Internet may have played an important role in the increasing consumption of anabolic drugs, especially among young people. Population studies have documented widespread androgen abuse among students all over the world in places such as South Africa, the United Kingdom, Scandinavia, and Australia (27) and (28). Moreover, a recent investigation of Polish adolescents revealed doping drugs abuse by 6.2% of young men and 2.9% of women (11).
Although the World Anti-Doping Code, adopted in 2003 and effective as of 2004, has proved to be a very powerful and effective tool in the harmonization of antidoping efforts worldwide, it has not been sufficient to tackle this illegal phenomenon. For this reason, we believe that it is necessary to increase monitoring and adopt more severe sanctions, particularly with regard to Internet sites.
References
1 G. Lippi, G. Banfi, M. Franchini and G.C. Guidi, New strategies for doping control, J Sports Sci 26 (2008), pp. 441–445. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (7)
2 G. Kanayama, A.J. Gruber, H.G. Pope Jr., J.J. Borowiecki and J.I. Hudson, Over-the-counter drug use in gymnasiums: an underrecognized substance abuse problem?, Psychother Psychosom 70 (2001), pp. 137–140. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (50)
3 G. Kanayama, H.G. Pope, G. Cohane and J.I. Hudson, Risk factors for anabolic-androgenic steroid use among weightlifters: a case-control study, Drug Alcohol Depend 71 (2003), pp. 77–86. Abstract | View Record in Scopus | Cited By in Scopus (52)
4 E.M. Komoroski and V.I. Rickert, Adolescent body image and attitudes to anabolic steroid use, Am J Dis Child 146 (1992), pp. 823–828. View Record in Scopus | Cited By in Scopus (52)
5 B.C. Melnik, Androgen abuse in the community, Curr Opin Endocrinol Diabetes Obes 16 (2009), pp. 218–223. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (6)
6 C.E. Yesalis, M.S. Bahrke and History of doping in sport, In: Performance-enhancing substances in sport and exercise (1st ed.), Eds Human Kinetics, Champaign, Illinois (2002) 1-20.
7 R.O. Voy and K. Deeter, Drugs, sport, and politics, Leisure Press, Champaign, Illinois (1991) 227.
8 T.D. Noakes, Tainted glory—doping and athletic performance, N Engl J Med 351 (2004), pp. 847–849. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (24)
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11 D. Rachoń, L. Pokrywka and K. Suchecka-Rachoń, Prevalence and risk factors of anabolic-androgenic steroids (AAS) abuse among adolescents and young adults in Poland, Soz Praventivmed 51 (2006), pp. 392–398. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (12)
12 S. Nilsson, A. Baigi, B. Marklund and B. Fridlund, The prevalence of the use of androgenic anabolic steroids by adolescents in a county of Sweden, Eur J Public Health 11 (2001), pp. 195–197. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (52)
13 G. Quaglio, A. Fornasiero, P. Mezzelani, S. Moreschini, F. Lugoboni and A. Lechi, Anabolic steroids: dependence and complications of chronic use, Intern Emerg Med 4 (2009), pp. 289–296. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (4)
14 A. Bonetti, F. Tirelli, A. Catapano, D. Dazzi, A. Dei Cas and F. Solito et al., Side effects of anabolic androgenic steroids abuse, Int J Sports Med 29 (2008), pp. 679–687. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (14)
15 T.A. Pagonis, N.V. Angelopoulos, G.N. Koukoulis and C.S. Hadjichristodoulou, Psychiatric side effects induced by supraphysiological doses of combinations of anabolic steroids correlate to the severity of abuse, Eur Psychiatry 21 (2006), pp. 551–562. Abstract | View Record in Scopus | Cited By in Scopus (20)
16 N.A. Hassan, M.F. Salem and M.A. Sayed, Doping and effects of anabolic androgenic steroids on the heart: histological, ultrastructural, and echocardiographic assessment in strength athletes, Hum Exp Toxicol 28 (2009), pp. 273–283. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (2)
17 E. van Breda, H.A. Keizer, H. Kuipers and B.H. Wolffenbuttel, Androgenic anabolic steroid use and severe hypothalamic-pituitary dysfunction: a case study, Int J Sports Med 24 (2003), pp. 195–196. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (19)
18 K. La Rosée, A. Schulz, M. Böhm and E. Erdmann, Acute cardiac failure in a bodybuilder, Dtsch med Wochenschr 122 (1997), pp. 1586–1590. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (5)
19 N.P. Boyadjiev, K.N. Georgieva, R.I. Massaldjieva and S.I. Gueorguiev, Reversible hypogonadism and azoospermia as a result of anabolic-androgenic steroid use in a bodybuilder with personality disorder: a case report, J Sports Med Phys Fitness 40 (2000), pp. 271–274. View Record in Scopus | Cited By in Scopus (24)
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21 F. Taylor and L. Levine, Clomiphene citrate and testosterone gel replacement therapy for male hypogonadism: efficacy and treatment costs, J Sex Med 7 (2010), pp. 269–276. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (2)
22 R.F. Casper, Aromatase inibhitors in ovarian stimulation, J Steroid Biochem Mol Biol 106 (2007), pp. 71–75. Abstract | View Record in Scopus | Cited By in Scopus (16)
23 S. Palomba, R. Pasquali, F. Orio Jr. and J.E. Nestler, Clomiphene citrate, metformin or both as first-step approach in treating anovulatory infertility in patients with polycystic ovary syndrome (PCOS): a systematic review of head-to-head randomized controlled studies and meta-analysis, Clin Endocrinol 70 (2009), pp. 311–321. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (6)
24 J.T.T. Bjork, R.R. Varma and H.I. Borkowf, Clomiphene citrate therapy in a patient with Laennec's cirrhosis, Gastroenterology 72 (1977), pp. 1308–1311. View Record in Scopus | Cited By in Scopus (3)
25 R.S. Tan and D. Vasudevan, Use of clomiphene citrate to reverse premature andropause secondary to steroid abuse, Fertil Steril 79 (2003), pp. 203–205. Article | PDF (60 K) | View Record in Scopus | Cited By in Scopus (17)
26 R.I. Wood, Anabolic-androgenic steroid dependence? Insights from animals and humans, Front Neuroendocrinol 29 (2008), pp. 490–506. Article | PDF (293 K) | View Record in Scopus | Cited By in Scopus (18)
27 S. Nilsson, Androgenic anabolic steroid use among male adolescents in Falkenberg, Eur J Clin Pharmacol 48 (1995), pp. 9–11. View Record in Scopus | Cited By in Scopus (43)
28 D.J. Handelsman and L. Gupta, Prevalence and risk factors for anabolic-androgenic steroid abuse in Australian high school students, Int J Androl 20 (1997), pp. 159–164. View Record in Scopus | Cited By in Scopus (53)
I.P. has nothing to disclose. C.C. has nothing to disclose. A.D. has nothing to disclose. T.S. has nothing to disclose. B.A. has nothing to disclose. D.A. has nothing to disclose. A.B. has nothing to disclose. M.C. has nothing to disclose.

 

[PLer1290]

There's no reason to assume it would work. GnRH agonists are nothing new and they have no potential for the treatment of hypogonadism. No studies support that any mechanism of dosing (1 microinjection, or multiple injections over time) any GnRH agonist will cause a permanent improvement in individuals with true hypogonadism. So the whole 1 small injection was NOT based on any science just sort of pulled out of the wind. That's good marketing and I applaud the peptide companies and do encourage experimentation by all individuals. But until a truly hypogonadic male (not temporarily induced low T from cycling) with low testosterone uses tripto to restore T levels above baseline I won't buy it. How you "feel" is not a good indication of recovery and and even blood tests after a cycle is not a good indication of tripto-induced recovery as there is no known baseline, no control, and no determining how it would compare to a SERM PCT or no PCT at all. Even comparing former blood tests does not show good results as testosterone levels can fluctuate dramatically throughout the day. It could only be proven if in a truly documented individual with permanently low testosterone, LH, FSH etc... can miraculously recover from a simple tripto administration.

Otherwise I just believe it will cause a spike in LH and FSH, followed by minor desensitization that bring you slightly below baseline, then followed by a return to baseline. The only benefit I see it having over SERMs is that you can avoid the side effects of SERMs. But SERMs have the benefit of still causing a high pulsatile release of LH and FSH through some indirect mechanism at the HPTA that will not lead to any significant deregulation. GnRH still works the same whether a little or alot is used, so I see using as no different than say trying to use a single shot of HCg during PCT or something.

I'm more interested in it for use as a PCT along with a SERM after a blast and cruise cycle.

 

[10brandonr]

I'm more interested in it for use as a PCT along with a SERM after a blast and cruise cycle.

Why in the hell? That's just like us meatheads lol! We don't think anything through.

First off blast and cruise = no PCT... unless you're trying to truly come off or something

Just because someone says that you can use tripto for PCT and then another says you can use a SERM, doesn't mean that if you combine them they will be even better than either alone. Where do we come to this conclusion? Not everything in the world is synergistic! lol.

Using tripto with a SERM IMO (and this is just an educated OPINION... but at least it's educated) will be essentially the same as using a SERM alone, this defeating the ONLY benefit tripto has over a SERM and that is that you don't have to take breast cancer drugs. You could use Nolva or something after tripto but then why did you take tripto in the first place.... and why would this qualify as a "better PCT" and what makes a better PCT... oh yeah if it "feels" better

But don't be offended, I just feel like I'm the only one playing devil's advocate otherwise everyone else seems to jump on every new thing that comes out... without actually reasoning things our first.

 

[PLer1290]

Why in the hell? That's just like us meatheads lol! We don't think anything through.

First off blast and cruise = no PCT... unless you're trying to truly come off or something

Just because someone says that you can use tripto for PCT and then another says you can use a SERM, doesn't mean that if you combine them they will be even better than either alone. Where do we come to this conclusion? Not everything in the world is synergistic! lol.

Using tripto with a SERM IMO (and this is just an educated OPINION... but at least it's educated) will be essentially the same as using a SERM alone, this defeating the ONLY benefit tripto has over a SERM and that is that you don't have to take breast cancer drugs. You could use Nolva or something after tripto but then why did you take tripto in the first place.... and why would this qualify as a "better PCT" and what makes a better PCT... oh yeah if it "feels" better

But don't be offended, I just feel like I'm the only one playing devil's advocate otherwise everyone else seems to jump on every new thing that comes out... without actually reasoning things our first.

Not a really long blast and cruise though, just about 8 months.

And I guess I'll stick with the tried and true SERMs then for PCT.

 

[10brandonr]

Not a really long blast and cruise though, just about 8 months.

And I guess I'll stick with the tried and true SERMs then for PCT.

Feel free to experiment man, I don't mean to discourage that. I don't wanna sound like I'm a know-it-all and that if you don't do what I do then your wrong. Cuz that not necessarily true, I just wanted to show the otherside of the story that no one else seems to be showing at the moment. I don't see much value in Tripto, but if anyone else believes it works then as far as I'm concerned it DOES for them, just not something I'll invest much into at the moment.