I have already passed this info to nothuman but thought I`d post it anyway for the rest of you. Melanocyte-stimulating hormone, known as MSH (MT2 is artificial version) is produced by the pituitary along with 3 other hormones in one long chain which is then cleeved, cut up by enzymes. One of the other hormones in chain is ACTH, adrenocorticotropin, controls the adrenal gland cortex. This region controls release of aldosterone and cortisol. When levels of MSH are artificially raised it suppresses the body`s natural production (just like shutting down your natural test on cycle). Unfortunately natural production of MSH is also tied to ACTH production. If MSH is shut down, so is ACTH (they are formed together). Reduced ACTH, means reduced aldosterone and cortisol. What I believe is happening is his blood plasma levels are being dropped, making the hematocrit % much higher. Basically dehydrated but not thirsty because thirst is controlled by other hormones, regions of brain. Basically a self induced addisons disease (mild level) but that should all reverse out once MT2 is dropped. Everybody on this board taking any supps needs to be getting blood work done or at minimum donating blood to get an idea of hematocrit, cholesterol, BP.