ill be following this
I understand this concern but every study for this drug and drugs like it is with dosages that are many many times the dosage one is using for PCT. I think the outcome is going to be hugely different for people taking this for prostate cancer at 3.75mg compared to people using this for PCT at 0.10mg(100mcg), 37.5 times lower dosage.
You're right... But where are the studies that say that a single administration of a low-dose of a GNRH agonist will reverse hypogonadism (essentially the goal of PCT)... there aren't any. Smaller dose just means smaller flare and less deregulation, but it won't cure anyones hypogonadism or be better than any other PCT protocol. There are plenty of studies that suggest that GNRH agonists are NOT good for reversing hypogonadism (this is essentially one of the basic reasons why it was synthesized in the first place) and that single injections just causes a return to baseline, and frequent and/or large injections cause dramatic deregulation. on the otherhand studies support that nolva, clomid, and even AIs are capable of driving FSH, LH, and testosterone levels well above baseline (so long as dosing is continuous).
I encourage experimentation but I guess all I'm wondering is what are people expecting from this more so than SERMs. Cuz no matter what once you stop the SERM or once the deregulation wears off from tripto, you always return to baseline, whether "your baseline" is low or high has nothing to do with what you use for PCT IMO...
What would you guys say about running Triptorelin with a SERM PCT? I'm limited to just guesswork on this one.
btw my problem with tripto is that I would guess that at these doses it fails to raise test, LH, or FSH even near as high as nolva and clomid.
Do you have citations or evidence to support this statement??
-T
Nevertheless SERMs work through a hypothalamus mechanism to spike gonadotropins and do not significantly alter the pulsatile nature of GNRH and do not cause any noticeable desensitization. This cannot be said with GNRH-a tho, which in my opinion cause a negative feedback not much different than a cycle itself. I don't see how a low-dose changes this. Its slightly analogous to AAS in that if you inject 100mgs of prop 1 time it will spike testosterone levels and will not shut you down, but nevertheless an insignificant negative feedback will downregulate natural production to a tiny extent. But after all is said and done the body will just return back to base. You didn't do much harm with the single prop injection, but you didn't do any good either.
Why not keep it public Twist? This is truly educational and can possible change the way we do PCT. Right now everything 10brandonr is writing is educational and speculative. We would love to hear your opinion as well. Wouldn't before and after bloodwork by some users give us a good idea on how this stuff is working at such a low amount? It would also show us if it works great by itself or if it may require the use of some other compounds as well.
I am on HRT and I am still reading on what others are feeling while using the product. I wanna have some kids later this year and I am going to have to decide if I am going to add some hmg to the hcg that i am currently using or go with the Trip
The Beggar