Mike Arnold
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Exactly . Do you know how much lower your igf levels will be with metformin at 500 850 or 1000 when using 4iu gh , 6iu gh. I'm curious because this is the info I look for my self now, and like you said will the benefits outweigh the negatives it's such a slippery slope, because when all of those things are combatting each other (gh , slin, met) it's really hard to see the differences especially because your research will never be exactly the same, weight and bf% wise.
And yea you can post marijuana lowers insulin levels and probably have 50 new bodybuilders smoking it because of something you said. It's that simple, my only argument was using it in the same cycle as you use insulin and gh because I see the potentials for the drug I just don't see it year round.
There are so many potential variables that it would be impossible to answer what someone's IGF-1 level will be when using a certain dose of met and GH. Personal response, drug-use, diet, etc--all can impact IGF-1 readings.
This is why I said before that posting studies is not always possible. Could you imagine anyone funding the type of research that would needed in order to come to even a semi-definitive conclusion? Yeah, right. This is why real-world experience is to vital to getting answers to bodybuilding related matters.
When feasible, we can have guys get bloodwork, but again, with so many potential variables, even with a dozen people doing bloodwork, we would only nip the tip of the iceberg on this one. In addition to the above-mentioned variables, we would also need to some way to confirm product legitimacy. In other words, unless the testers were using pharm-grade PED's, we could not be sure that the dosages, and therefore the results, were accurate. There's just so many possible things which could change the scenario, some of which are in our control and some which aren't..
When dealing with individuals, I look at the bigger picture in order to determine whether or not I think metformin use is warranted. What's their diet like? What PED's are they using, in what dosages, and for how long? Are they displaying any signs of insulin resistance, and a half-dozen other things.