GH experts,
Please chime in. Here is a discussion I have recently had with a friend. When people buy non-Phram GH, they mix the lypolyzied powder with just regular bacteriostatic water. However, the liquid that Pharm grade GH is mixed with is not just bacteriostatic water. Have you guys ever checked out what is in the liquid that something like Genotropin or Hmatrope comes in? Here is the ingredient list taken from the Genotropin web site
GENOTROPIN 5 mg is dispensed in a two-chamber cartridge. The front chamber contains recombinant somatropin 5.8 mg, glycine 2.2 mg, mannitol 1.8 mg, sodium dihydrogen phosphate anhydrous 0.32 mg, and disodium phosphate anhydrous 0.31 mg; the rear chamber contains 0.3% m-Cresol (as a preservative) and mannitol 45 mg in 1.14 mL water for injection. The GENOTROPIN 5 mg two-chambered cartridge contains 5.8 mg of somatropin. The reconstituted concentration is 5 mg/ml. The cartridge contains overfill to allow for delivery of 1ml containing the stated amount of GENOTROPIN – 5 mg.
http://labeling.pfizer.com/ShowLabeling.aspx?id=577
Should we also be using mannitol and m-Cresol (not even sure what this one is) to mix the GH in? If not, why is Pfizer using them?
Please chime in. Here is a discussion I have recently had with a friend. When people buy non-Phram GH, they mix the lypolyzied powder with just regular bacteriostatic water. However, the liquid that Pharm grade GH is mixed with is not just bacteriostatic water. Have you guys ever checked out what is in the liquid that something like Genotropin or Hmatrope comes in? Here is the ingredient list taken from the Genotropin web site
GENOTROPIN 5 mg is dispensed in a two-chamber cartridge. The front chamber contains recombinant somatropin 5.8 mg, glycine 2.2 mg, mannitol 1.8 mg, sodium dihydrogen phosphate anhydrous 0.32 mg, and disodium phosphate anhydrous 0.31 mg; the rear chamber contains 0.3% m-Cresol (as a preservative) and mannitol 45 mg in 1.14 mL water for injection. The GENOTROPIN 5 mg two-chambered cartridge contains 5.8 mg of somatropin. The reconstituted concentration is 5 mg/ml. The cartridge contains overfill to allow for delivery of 1ml containing the stated amount of GENOTROPIN – 5 mg.
http://labeling.pfizer.com/ShowLabeling.aspx?id=577
Should we also be using mannitol and m-Cresol (not even sure what this one is) to mix the GH in? If not, why is Pfizer using them?