OuchThatHurts
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This is interesting:
”GGT is a nonspecific marker that is known to rise in patients with type 2 diabetes. In epidemiological studies, it has a positive association with alcohol intake, cigarette smoking, coronary heart disease, BMI, systolic blood pressure, serum triglyceride, heart rate, uric acid, and hematocrit [most of which are common among BBers]. It has an inverse association with physical activity level.[6] Because GGT increases in diabetes, and increases as BMI increases, it has been proposed as another marker of insulin resistance.
To determine whether elevated GGT could predict the development of type 2 diabetes, a prospective cohort study of 7,458 nondiabetic men aged 40-59 years was conducted for 12 years.[7]Mean serum GGT at the start of the study was significantly higher in the 194 men who developed type 2 diabetes than in the rest of the cohort who did not develop diabetes (20.9 vs. 15.3 units/l, P < 0.0001). The association was independent of serum glucose and BMI.”
6. Wannamethee G, Ebrahim S, Shaper AG: Gamma-glutamyltransferase: determinants and associations with mortality from ischaemic heart disease and all causes.
Am J Epidemiol 42:699-708, 1995
7. Perry IJ, Wannamethee SG, Shaper AG: Prospective study of serum gamma-glutamyltransferase and risk of NIDDM.
Diabetes Care 21: 732-737,1998
”GGT is a nonspecific marker that is known to rise in patients with type 2 diabetes. In epidemiological studies, it has a positive association with alcohol intake, cigarette smoking, coronary heart disease, BMI, systolic blood pressure, serum triglyceride, heart rate, uric acid, and hematocrit [most of which are common among BBers]. It has an inverse association with physical activity level.[6] Because GGT increases in diabetes, and increases as BMI increases, it has been proposed as another marker of insulin resistance.
To determine whether elevated GGT could predict the development of type 2 diabetes, a prospective cohort study of 7,458 nondiabetic men aged 40-59 years was conducted for 12 years.[7]Mean serum GGT at the start of the study was significantly higher in the 194 men who developed type 2 diabetes than in the rest of the cohort who did not develop diabetes (20.9 vs. 15.3 units/l, P < 0.0001). The association was independent of serum glucose and BMI.”
6. Wannamethee G, Ebrahim S, Shaper AG: Gamma-glutamyltransferase: determinants and associations with mortality from ischaemic heart disease and all causes.
Am J Epidemiol 42:699-708, 1995
7. Perry IJ, Wannamethee SG, Shaper AG: Prospective study of serum gamma-glutamyltransferase and risk of NIDDM.
Diabetes Care 21: 732-737,1998