Assuming that your daily food consumption isn't crazy high, less meals may be better both for anabolism and health. Intermittent bolus feeding has been associated as a more physiological release pattern of gastrointestinal tract hormones and enhances protein accretion .
Contrary to common practice, the provision of protein/amino acids as a continuous administrationi significantly limits protein synthesis whereas intermittent feeding maximally stimulates skeletal muscle synthesis. In addition to its adverse effects on skeletal muscle synthesis, continuous feeding is unphysiological and has adverse effects on glucose and lipid metabolism and gastrointestinal function.
Muscles are receptive to the anabolic effects of dietary protein, and in particular the EAA leucine, for only a short period (i.e. about 2–3 h) in the rested state. Thereafter, MPS exhibits tachyphylaxis despite continued EAA availability. Muscles are receptive to the anabolic effects of dietary protein, and in particular the EAA leucine, for only a short period (i.e. about 2–3 h). Thereafter, MPS exhibits tachyphylaxis despite continued EAA availability and sustained mechanistic target of rapamycin complex 1 signalling. The most notable characteristic of this ‘muscle full’ phenomenon is that it cannot be overcome by proximal intake of additional nutrient signals/substrates regulating MPS; meaning a refractory period exists before a next stimulation is possible.