Meditrope questions

[VakarianSK]

Yeah I got it backwards. 22kd is 191 AA
20kd is 176 AA. It's missing the lipolytic fragment. It's also not the dominant form in nature. Humans have 76% 22kd, 10% 20kd. 14% other stuff. The other stuff isn't that good. Some of it is inhibitory. So the rumor is generics are 20kd, but I'm Sure meditrope is 22kd

Glad to see you on PM Dr Todd, and I think you are correct. And if what you just said is true then all 191 AA is 22kd and that would mean as long as test facilities are only looking at 191 AA when checking for purity and dimer and the product tests good then it must be 22kd.

 

[ChaseIrons]

TP I am 100% in to help out in any way I can. Whether it be research or experimentation or anything. Just let me know.

How much gh are you using a day now?

We are even ready to do an experiment for the community to have this put to rest once and for all if the excipients need to be changed in the vials cause more or less water retention. If people are interested in it and want maybe do this than we can ask the factory to make very small batches of like 40-50 kits with different excipients and see what happens. If Pm community is interested in it than we can play this game also.. But we need some experts in this field to guide us. Chaseiron had someone who is expert in this field. If maybe he can chime in. I personally think its he purity of the product. Like for example quite a few people who have used our golds mauves and blacktop say they get least water retention from gold tops. Only difference between gold tops and black/mauve tops is the purity . rest excipients are the same for all colors.

​

sure I’d test 2 vials a day for science

 

[VakarianSK]

How much gh are you using a day now?

sure I’d test 2 vials a day for science

10IU

 

[ChaseIrons]

10IU

Damn bro is getting aggressive on that trt

 

[Todd Lee]

Damn bro is getting aggressive on that trt

Chase, or anyone else, do you have lab reports on meditropin showing its 22kd or 191 AA? I'm sure there are hundreds of posts but I just started using this the other day and I'm not sophisticated enough to find them. The reason is I want to do a video indicating that meditropes are 191 22kd real deal gh.

 

[ChaseIrons]

Chase, or anyone else, do you have lab reports on meditropin showing its 22kd or 191 AA? I'm sure there are hundreds of posts but I just started using this the other day and I'm not sophisticated enough to find them. The reason is I want to do a video indicating that meditropes are 191 22kd real deal gh.

No i have no idea. Just make a video on it anyway so people will stop buying serostim

 

[Todd Lee]

No i have no idea. Just make a video on it anyway so people will stop buying serostim

Tp said he has a main thread where people post their lab reports. Do you know what that is

 

[j2048b]

No i have no idea. Just make a video on it anyway so people will stop buying serostim

Why to stopping the purchase of sero’s?? Cost overall or because someone wants them all? Hahah i kid i kid… but seriously

 

[M@NU]

Tp said he has a main thread where people post their lab reports. Do you know what that is

https://thinksteroids.com/community/threads/tp-hgh-black-tops-janoshik-test-results.134420932/

this is the most recent one of blacktops and i am amazed by the great result.
98% purity and no dimer is great.
I think @janoshik mentioned in one of the threads that he has not come along 192AA HGH during his tests

 

[pickapeck]

I've used the Medi black tops for over a year and never had water retention any more than with pharma grade pens. I am not using a lot but am a person that tends to hold water on the less purity brands.

 

[Mufasa123]

think @janoshik mentioned in one of the threads that he has not come along 192AA HGH during his tests

I recall this as well. It's basically a non issue in the past couple decades now. Still some stuff on the net making people ask. My recollection/memory anyway.

 

[VakarianSK]

If you can get this info that would be bad ass. there was a comment on that video that was interesting that might give some insight??

"All of these most likely are in final formulation, then lyophilized in vials, so they're neat liquids then turned to powder. Final formulation of the buffer can be directly related to stability. Shipping conditions in a lyophilzed state can also affect stability when reconstituted. I've done SDS-PAGE on Chinese generic. I did not notice any degradation or aggregation on my samples, but I did notice a 1-3 kDa shift. Observing uniprot accession P01241, there are documented isoforms. My understanding is that the isoforms 2 and 3 can have missense point mutations that suposedly do not affect bioactivity, but obviously, that hasn't been documented in any study I've found. Pharma exclusively uses somatropin isoform P01241-1, which is the canonical sequence at 22 kDa. Chinese generics sequence I tested was observed at 20 kDa. HPLC testing will observe both of these as hGH. Source - protein chemist over a decade industry experience, analytical chemist over 2 years experience."

Yeah I got it backwards. 22kd is 191 AA
20kd is 176 AA. It's missing the lipolytic fragment. It's also not the dominant form in nature. Humans have 76% 22kd, 10% 20kd. 14% other stuff. The other stuff isn't that good. Some of it is inhibitory. So the rumor is generics are 20kd, but I'm Sure meditrope is 22kd

I wanted to send a reply to both of you because I had some interesting information I wanted to share with you both.

So I have been in contact with @janoshik and he was kind enough to help me out with some research that everyone seems to have been doing in regards to hgh and isoforms. Janoshik gave me permission to share the below with the community and I cannot thank him enough!


VakarianSK:
"
There has been a lot of conversation lately in our industry that started out on Youtube and moved its way into Professional Muscle. And I can not think of anyone but you who could answer this question.

The age old debate pharm vs generic hgh has surged again, except now some people think the reason that pharm is superior to generic is because generic is actually 20kd instead of 22kd (which is what pharm grade uses).

From my unserstanding though if an hgh product is 191 AA than it must be 22kd. If it is anything more or less than 22kd then it would no longer be 191 AA. Is this correct?

If the above is correct I would also like to ask about your services. When someone sends a sample of hgh to you and you test the purity and dimer are you only testing it as 191 AA? Meaning that if someone did send you a sample that is 20kd then it would not test out with a high purity or it would test even at 0 purity.

Thanks for taking time to read this email and I look forward to your response and if you consent I would also like to share your answer with some others in the industry.
"

JanoShik:
"
You are correct in everything. There is no 20kDa HGH on the market. Please, feel free to quote me.
"


So this should answer the 22kd vs 20kd questions that have popped up recently.

 

[skyblob]

I usually just mix it in the vial then put in in the fridge and check in like 20 mins and it's always crystal clear and fully dissolved. Honestly it may not even take that much time lol. I'm not sure what you mean by purple but I've done this with blacks, golds, and greys.

Which one you liked the most? I can only have access to black or gold since im in canada and looking for the lowest dimmer and least water retention.

 

[VakarianSK]

Which one you liked the most? I can only have access to black or gold since im in canada and looking for the lowest dimmer and least water retention.

I havn't used them long enough to really give a good recommendation. But I will say that gold is generally higher purity. However a recent member of the session group did hplc testing on the batch #126 black tops showing 98.302% purity and 0 dimer.

 

[skyblob]

I havn't used them long enough to really give a good recommendation. But I will say that gold is generally higher purity. However a recent member of the session group did hplc testing on the batch #126 black tops showing 98.302% purity and 0 dimer.

Thats crazy 0% dimer . Wow

 

[VakarianSK]

Thats crazy 0% dimer . Wow

From what I can tell TP doesn't mess around lol.

 

[skyblob]

From what I can tell TP doesn't mess around lol.

I just ordered some loll

 

[ChaseIrons]

I wanted to send a reply to both of you because I had some interesting information I wanted to share with you both.

So I have been in contact with @janoshik and he was kind enough to help me out with some research that everyone seems to have been doing in regards to hgh and isoforms. Janoshik gave me permission to share the below with the community and I cannot thank him enough!


VakarianSK:
"
There has been a lot of conversation lately in our industry that started out on Youtube and moved its way into Professional Muscle. And I can not think of anyone but you who could answer this question.

The age old debate pharm vs generic hgh has surged again, except now some people think the reason that pharm is superior to generic is because generic is actually 20kd instead of 22kd (which is what pharm grade uses).

From my unserstanding though if an hgh product is 191 AA than it must be 22kd. If it is anything more or less than 22kd then it would no longer be 191 AA. Is this correct?

If the above is correct I would also like to ask about your services. When someone sends a sample of hgh to you and you test the purity and dimer are you only testing it as 191 AA? Meaning that if someone did send you a sample that is 20kd then it would not test out with a high purity or it would test even at 0 purity.

Thanks for taking time to read this email and I look forward to your response and if you consent I would also like to share your answer with some others in the industry.
"

JanoShik:
"
You are correct in everything. There is no 20kDa HGH on the market. Please, feel free to quote me.
"


So this should answer the 22kd vs 20kd questions that have popped up recently.

yup, everyone buy generics now please

 

[VakarianSK]

greys harder to get but got of medis but only for the ingredients used and not the percentage

Disodium hydrogen phosphate dodecahydrate
Sodium phosphate dibasic dihydrate
Glycine
Boloxane 188
Mannitol
Disodium EDTA

The above are used in meditropes

Hey TP just wanted to check in to see if you were able to get in contact with The Grey Top manufacturers on their list of ingredients. Thanks and keep up the great work!

 

[theprovider]

Hey TP just wanted to check in to see if you were able to get in contact with The Grey Top manufacturers on their list of ingredients. Thanks and keep up the great work!

Trying to get that info. Hoping for the best. When i do will post here.. Thanks